Zobrazeno 1 - 10
of 26
pro vyhledávání: '"Brendan J. Keating"'
Autor:
Juhi Kumar, Eric D. Elftmann, Nikhil Nair, Khaldoun Al-Romaih, Krzysztof Kiryluk, Francesca Zanoni, Ryan Kellogg, Samuel B. Goldfarb, Brendan J. Keating, Sarah J. Kizilbash, Ahmed A. Metwally, Elizabeth B. Rand, Janaiya Reason, Benjamin Rolnik, Alexander Lee, Venkata S. Chaluvadi, Taisa J. Kohut, Michael Snyder, Lina Ibrahim, Feyisope R. Eweje, Robert R. Redfield, Sandra Amaral, Eyas Mukhtar, Joseph W. Rossano, Jay A. Fishman, Hui Gao, Matthew J. O'Connor, Amir Bahmani, Fatima Abdullah Alrubaish, Andrew W. Brooks, Amein K. Al-Ali, Tejas Mishra, Meng Wang, Maha Al-Mozaini, Eric Li, Fahad Al-Muhanna, Robert A. Montgomery, Arash Alavi, Pablo G. Sanchez, Stephen D. Marks, Alexander Honkala, Krista A. Moore, Pamala A. Jacobson, Ranganath G. Kathawate, Gireesh K. Bogu
Publikováno v:
Transplant International
Summary The increasing global prevalence of SARS‐CoV‐2 and the resulting COVID‐19 disease pandemic pose significant concerns for clinical management of solid organ transplant recipients (SOTR). Wearable devices that can measure physiologic chan
Autor:
Magdalena Harakalova, Benjamin Meder, Philippe Charron, Manuel Gómez-Bueno, Jorg J. A. Calis, François Cambien, David-Alexandre Trégouët, Maurizia Grasso, Steven McGinn, Uwe Völker, Thomas Meitinger, Stefan Weiss, L. Duboscq-Bidot, Richard Dorent, Vera Regitz-Zagrosek, Folkert W. Asselbergs, Hélène Blanché, Olivier Dubourg, Patrick Lacolley, Pierre Boutouyrie, Delphine Bacq-Daian, Vincent Fontaine, Volker Ruppert, Marine Germain, K Lehnert, Jean-Noël Trochu, Stuart A. Cook, Angélique Curjol, Brendan J. Keating, Ibticem Raji, Anne Boland, J. Erdmann, Michael Morley, Jean-François Aupetit, Paloma Remior, Luigi Tavazzi, Gérard Roizès, Michal Mokry, Konstantin Strauch, Richard Isnard, Jean-Philippe Empana, Robert Olaso, Kenneth B. Marguiles, Zofia T. Bilińska, Stephan B. Felix, Marcus Dörr, Thomas P. Cappola, Stefan Blankenberg, Jan Haas, Céline Besse, Jean-François Deleuze, Christine E. Seidman, Christian Hengstenberg, Jessica van Setten, Hakon Hakonarson, Sanjay K Prasad, Daiane Hemerich, Pascal de Groote, Thomas Wichter, Alain van Mil, Michel Komajda, Renee Maas, Carole Proust, Declan P. O'Regan, Xavier Jouven, Ganapathi Varma Saripella, Georgios Kararigas, Eloisa Arbustini, Jin Li, Klaus Stark, Laurent Fauchier, Flavie Ader, Melanie Waldenberger, Martina Müller-Nurasyid, Eric Villard, Sophie Garnier
Publikováno v:
European heart journal, 42(20), 2000-2011. Oxford University Press
European Heart Journal
European Heart Journal, Oxford University Press (OUP): Policy B, 2021, ⟨10.1093/eurheartj/ehab030⟩
European Heart Journal, 2021, 42 (20), pp.2000-2011. ⟨10.1093/eurheartj/ehab030⟩
European Heart Journal
European Heart Journal, Oxford University Press (OUP): Policy B, 2021, ⟨10.1093/eurheartj/ehab030⟩
European Heart Journal, 2021, 42 (20), pp.2000-2011. ⟨10.1093/eurheartj/ehab030⟩
Aims Our objective was to better understand the genetic bases of dilated cardiomyopathy (DCM), a leading cause of systolic heart failure. Methods and results We conducted the largest genome-wide association study performed so far in DCM, with 2719 ca
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2d2fb4a5751c8873677e1b542fdd8c3a
https://pure.amc.nl/en/publications/genomewide-association-analysis-in-dilated-cardiomyopathy-reveals-two-new-players-in-systolic-heart-failure-on-chromosomes-3p251-and-22q1123(8df098a2-4e2b-436a-8594-9c6ed3e705d8).html
https://pure.amc.nl/en/publications/genomewide-association-analysis-in-dilated-cardiomyopathy-reveals-two-new-players-in-systolic-heart-failure-on-chromosomes-3p251-and-22q1123(8df098a2-4e2b-436a-8594-9c6ed3e705d8).html
Autor:
Alexander P. Maxwell, Peter J. Conlon, Jessica van Setten, Brendan J. Keating, Claire Kennedy, Jamie P. Traynor, Paul J. Phelan, M. Lee Sanders, Fiona A. Chapman, Caragh P. Stapleton, Kelly A. Birdwell, Amy Jayne McKnight, Patrick B. Mark, Alan G. Jardine, Gianpiero L. Cavalleri
Publikováno v:
American Journal of Transplantation, 19(3), 801. Blackwell Publishing Asia Pty Ltd
Stapleton, C P, Birdwell, K A, McKnight, A J, Maxwell, A P, Mark, P B, Sanders, M L, Chapman, F A, van Setten, J, Phelan, P J, Kennedy, C, Jardine, A, Traynor, J P, Keating, B, Conlon, P J & Cavalleri, G L 2019, ' Polygenic risk score as a determinant of risk of non-melanoma skin cancer in a European-descent renal transplant cohort ', American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons, vol. 19, no. 3, pp. 801-810 . https://doi.org/10.1111/ajt.15057
Stapleton, C P, Birdwell, K A, McKnight, A J, Maxwell, A P, Mark, P B, Sanders, M L, Chapman, F A, van Setten, J, Phelan, P J, Kennedy, C, Jardine, A, Traynor, J P, Keating, B, Conlon, P J & Cavalleri, G L 2019, ' Polygenic risk score as a determinant of risk of non-melanoma skin cancer in a European-descent renal transplant cohort ', American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons, vol. 19, no. 3, pp. 801-810 . https://doi.org/10.1111/ajt.15057
Renal transplant recipients have an increased risk of non-melanoma skin cancer (NMSC) compared to in the general population. Here, we show polygenic risk scores (PRS) calculated from genome-wide association studies (GWAS) of NMSC in general, non-tran
Autor:
Melissa L. Wilson, Brendan J. Keating, Sue A. Ingles, Kathryn J. Gray, Hooman Mirzakhani, Jeffrey C. Murray, Hakon Hakonarson, Richa Saxena, Errol R. Norwitz, SA Karumanchi, Andrew Bjonnes, Charles J. Lockwood, Brian T. Bateman, Berta Almoguera, Vesela P. Kovacheva, Thomas F. McElrath
Publikováno v:
BJOG : an international journal of obstetrics and gynaecology. 128(1)
OBJECTIVE To assess whether women with a genetic predisposition to medical conditions known to increase pre-eclampsia risk have an increased risk of pre-eclampsia in pregnancy. DESIGN Case-control study. SETTING AND POPULATION Pre-eclampsia cases (n
Autor:
Kathryn J. Gray, Jeffrey C. Murray, Melissa L. Wilson, Sue A. Ingles, Hakon Hakonarson, Charles J. Lockwood, Errol R. Norwitz, Brian T. Bateman, Hooman Mirzakhani, S. Ananth Karumanchi, Berta Almoguera, Vesela P. Kovacheva, Thomas F. McElrath, Andrew Bjonnes, Brendan J. Keating, Richa Saxena
ObjectiveTo assess whether women with a genetic predisposition to medical conditions known to increase preeclampsia risk have an increased risk of preeclampsia in pregnancy.DesignCase-control study.Setting and populationPreeclampsia cases (n=498) and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f0a2b3976f49dc499d2b9e188f603855
https://doi.org/10.1101/2020.03.04.976472
https://doi.org/10.1101/2020.03.04.976472
Autor:
Céline Besse, François Cambien, Folkert W. Asselbergs, Robert Olaso, Jeanette Erdman, Benjamin Meder, Stephan B. Felix, Stefan Weiss, Laurent Fauchier, Konstantin Strauch, Luigi Tavazzi, Anne Boland, Gérard Roizès, Pascal DeGroote, Renee Maas, Melanie Waldenberger, Ganapathi Varma Saripella, Pablo García-Pavía, Brendan J. Keating, Vera Regitz-Zagrosek, Marine Germain, Stefan Blankenberg, Jessica van Setten, Eloisa Arbustini, Pierre Boutouyrie, Carole Proust, Delphine Bacq-Daian, Hemerich Daiane, Sophie Garnier, Michal Mokry, Richard Dorent, Martina Müller-Nurasyid, Philippe Charron, Maurizia Grasso, Steven Mc Ginn, Vincent Fontaine, Uwe Völker, Patrick Lacolley, Thomas Meitinger, Christine E. Seidman, Ibticem Raji, David-Alexandre Trégouët, Jean-Noël Trochu, Thomas Wichter, Jörg Callis, Alain van Mil, Jean-François Deleuze, Declan P. O'Regan, Xavier Jouven, Jin Li, Klaus Stark, Eric Villard, Stuart A. Cook, Hakon Hakonarson, Michael Morley, Kenneth B. Marguiles, Sanjay K Prasad, Volker Ruppert, Jean-François Aupetit, Jean-Philippe Empana, Marcus Dörr, Thomas P. Cappola, Michel Komajda, Magdalena Harakalova, Christian Hengstenberg, Hélène Blanché, Angélique Curjol, L. Duboscq-Bidot, Richard Isnard, Olivier Dubourg, K Lehnert
SummaryWe present the results of the largest genome wide association study (GWAS) performed so far in dilated cardiomyopathy (DCM), a leading cause of systolic heart failure and cardiovascular death, with 2,719 cases and 4,440 controls in the discove
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5fc3119dd5f3a16ea14b94c575d999ba
https://doi.org/10.1101/2020.02.28.969147
https://doi.org/10.1101/2020.02.28.969147
Autor:
Thomas F. McElrath, Charles J. Lockwood, Brendan J. Keating, Melissa L. Wilson, Audrey F. Saftlas, Dale L. Bodian, Elizabeth W. Triche, Jeffrey C. Murray, Elisabeth Klein, Kathi Huddleston, Hakon Hakonarson, Hooman Mirzakhani, Josephine Hoh, Richa Saxena, Berta Almoguera, S. Ananth Karumanchi, Brian T. Bateman, Vesela P. Kovacheva, Kathryn J. Gray, Andrew Bjonnes, Errol R. Norwitz, Andrew T. DeWan, Sue A. Ingles
Publikováno v:
Hypertension. 72:408-416
The genetic susceptibility to preeclampsia, a pregnancy-specific complication with significant maternal and fetal morbidity, has been poorly characterized. To identify maternal genes associated with preeclampsia risk, we assembled 498 cases and 1864
Autor:
Kelli K. Ryckman, Elizabeth W. Triche, Audrey F. Saftlas, Caitlin J. Smith, Andrew Bjonnes, Josephine Hoh, Brendan J. Keating, Jennifer G. Robinson, Richa Saxena, Cassandra N. Spracklen, Patrick Breheny, Andrew T. DeWan
Publikováno v:
Hypertension in Pregnancy. 36:30-35
To examine the association between genetic predisposition to elevated C-reactive protein (CRP)and risk for preeclampsia using validated genetic loci for C-reactive protein.Preeclampsia cases (n = 177) and normotensive controls (n = 116) were selected
Autor:
Caragh P. Stapleton, Andreas Heinzel, Weihua Guan, Peter J. van der Most, Jessica van Setten, Graham M. Lord, Brendan J. Keating, Ajay K. Israni, Martin H. de Borst, Stephan J.L. Bakker, Harold Snieder, Michael E. Weale, Florence Delaney, Maria P. Hernandez-Fuentes, Roman Reindl-Schwaighofer, Rainer Oberbauer, Pamala A. Jacobson, Patrick B. Mark, Fiona A. Chapman, Paul J. Phelan, Claire Kennedy, Donal Sexton, Susan Murray, Alan Jardine, Jamie P. Traynor, Amy Jayne McKnight, Alexander P. Maxwell, Laura J. Smyth, William S. Oetting, Arthur J. Matas, Roslyn B. Mannon, David P. Schladt, David N. Iklé, Gianpiero L. Cavalleri, Peter J. Conlon
Publikováno v:
Am J Transplant
American Journal of Transplantation, 19(8), 2262-2273. Wiley
American Journal of Transplantation, 19(8), 2262-2273. Wiley
Genetic variation across the human leukocyte antigen loci is known to influence renal-transplant outcome. However, the impact of genetic variation beyond the human leukocyte antigen loci is less clear. We tested the association of common genetic vari
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::80f0fdd84d7f673295f53f196b51d5e6
https://europepmc.org/articles/PMC6989089/
https://europepmc.org/articles/PMC6989089/
Autor:
Heribert Schunkert, Wolfgang Koenig, Jessica van Setten, Meena Kumari, Johan Ärnlöv, J. Wouter Jukema, Vinicius Tragante, Alanna C. Morrison, Bradford B. Worrall, Brendan J. Keating, Alexander Teumer, Vilmantas Giedraitis, Tom Wilsgaard, Nilesh J. Samani, Barbara Thorand, Patricia B. Munroe, Rainer Malik, Melanie Waldenberger, Christopher P. Nelson, Sebastian E. Baumeister, Aroon D. Hingorani, Stéphanie Debette, Tove Fall, Patrik K. E. Magnusson, Nora Franceschini, Anders Larsson, Andrew P. Morris, Folkert W. Asselbergs, Maryam Kavousi, Oscar H. Franco, Jeanette Erdmann, Jonathan Marchini, Mika Kivimäki, Ivana Išgum, Fotios Drenos, N. Charlotte Onland-Moret, Bjørn Odvar Eriksen, Aicha Soumare, Christopher J. O'Donnell, Ingrid Toft, Paul I.W. de Bakker, Johannes Arpegård, Jacqueline de Graaf, Abbas Dehghan, Delilah Zabaneh, Michael V. Holmes, Yvonne T. van der Schouw, Alexander P. Reiner, André G. Uitterlinden, Christa Meisinger, Janine F. Felix, Erik Ingelsson, Lars Lind, Martin Dichgans, Marcus Dörr, Albert Hofman, Sanaz Sedaghat, Lambertus A. Kiemeney, Joshua C. Bis, Jens Baumert, Tessel E. Galesloot, Hester M. den Ruijter, Gerard Pasterkamp, Annette Peters, Naveed Sattar, Nancy L. Pedersen, Pim van der Harst, Stella Trompet, Per Svensson, Riyaz S. Patel, Philippe Amouyel, Sander W. van der Laan
Publikováno v:
Journal of the American College of Cardiology. 68:934-945
BACKGROUND Epidemiological studies show that high circulating cystatin C is associated with risk of cardiovascular disease (CVD), independent of creatinine-based renal function measurements. It is unclear whether this relationship is causal, arises f