Zobrazeno 1 - 10
of 22
pro vyhledávání: '"621"'
Autor:
Hongbing Shen, Ying Li, Yulin Wu, Cheng Chen, Feng Chen, Zhiming Sun, Hongxin Pan, Jian Zhou, Lei Ba, Jinna Zhao
Publikováno v:
Archives of Medical Research. 41:599-605
Background and Aims Estrogen receptor beta (ESR2) plays an important role in cardiovascular physiology and blood pressure regulation, whereas estrogens may influence gene expression, growth, and cellular differentiation in target tissues by activatin
Autor:
T. Mary Fujiwara, G Aubin, Marc De Braekeleer, Linda Lamoureux, Maria Gerdes, J Daigneault, F Simard, Leonor Ferreira-Rajabi, Rima Rozen, Kenneth Morgan
Publikováno v:
American Journal of Medical Genetics. 42:360-364
The French-Canadian population in the Saguenay-Lac St. Jean region of northeastern Quebec has an elevated frequency of cystic fibrosis (CF). The average incidence of cystic fibrosis was 1 in 891 births and the prevalence of CF carriers was estimated
Autor:
Subburaj Kadarkarai Samy, Uma Jyothi Kommoju, Jaya Prasad Kotla, Lakshmi Velaga, Jayaraj Maruda, Kumuda Irgam, Battini Mohan Reddy
Publikováno v:
Indian Journal of Medical Research, Vol 143, Iss 4, Pp 455-463 (2016)
The Indian Journal of Medical Research
The Indian Journal of Medical Research
Background & objectives: The genome-wide association studies (GWAS) have shown an association of type 2 diabetes mellitus (T2DM) with several novel genes. We report here the findings on the pattern of genetic association of three genes (CDKAL1, CDKN2
Autor:
Dilare Adi, Xiao-Dong He, Zhen-Yan Fu, Fen Liu, Yong-Tao Wang, Yi-Tong Ma, Ying-Hong Wang, Asiya Abudesimu
Publikováno v:
Medicine
Disabled-2 (Dab2) is a clathrin and cargo-binding endocytic adaptor protein that plays a role in cellular trafficking of low-density lipoprotein receptor (LDLR). However, little is known about its involvement in coronary artery disease (CAD). Here, w
Autor:
Gabriel Cuellar-Partida, Nicholas G. Martin, Johannes R. Vingerling, Alex W. Hewitt, André G. Uitterlinden, Grant W. Montgomery, Richard A. Mills, Matthew A. Brown, Stuart MacGregor, Kathryn P. Burdon, Cornelia M. van Duijn, Roger C. W. Wolfs, Wishal D. Ramdas, David A. Mackey, Albert Hofman, Jamie E Craig, Seyhan Yazar, Virginie J. M. Verhoeven, Adriana I Iglesias, Elisabeth M. van Leeuwen, Craig E. Pennell, Henriët Springelkamp, Sionne E. M. Lucas, Caroline C W Klaver
Publikováno v:
Human Molecular Genetics, 24(17), 5060-5068. Oxford University Press
Keratoconus is a degenerative eye condition which results from thinning of the cornea and causes vision distortion. Treatments such as ultraviolet (UV) cross-linking have proved effective for management of keratoconus when performed in early stages o
Publikováno v:
The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease. 21(6)
Setting Tuberculosis (TB) has decreased substantially in New York City (NYC), but progress has slowed in recent years. Continued declines will require novel approaches tailored to foreign-born populations. Objective To describe TB epidemiology among
Autor:
Rebecca Lucas-Roxburgh, Laryssa Howe, Ursula van den Heever, Bruce Lockett, Ruth M. Williams, Jackie Benschop
Publikováno v:
PLoS ONE, Vol 12, Iss 10, p e0186424 (2017)
PLoS ONE
PLoS ONE
Background The incidence of oropharyngeal cancer (OPC) in New Zealand (NZ) has more than doubled over the last 14 years with 126 cases in 2010. Overseas studies have shown that human papillomavirus (HPV) plays a significant role in the development of
Autor:
Tatiana M. Lopera-Mesa, Kazutoyo Miura, Michael P. Fay, Michael Krause, Mahamadou Diakite, Karim Traore, Steve M. Taylor, Rick M. Fairhurst, Saibou Doumbia, Wenjuan Gu, Gregory Tullo, Seidina A. S. Diakite, Carole A. Long, Jennifer M. Anderson, Samuel E. Moretz, Abdoul S. Keita, Mory Doumbouya, Drissa Konaté, Ababacar Diouf
Publikováno v:
The Lancet. Haematology. 2(4)
Red blood cell variants protect African children from severe falciparum malaria. However, their individual and interactive effects on mild disease and parasite density, and their modification by age-dependent immunity, are poorly understood. In this
Publikováno v:
Human Genetics. 101:208-211
Cystic fibrosis (CF) has a high incidence in the French-Canadian population of Saguenay Lac-Saint-Jean (Quebec). The A455E mutation accounts for 8.3% of the CF chromosomes. This mutation was shown to be associated with a milder lung disease in the Du
Autor:
Agnieszka Maciejewska-Karlowska, Nir Eynon, David Bishop, Paweł Cięszczyk, Zbigniew Jastrzębski, Marek Sawczuk, Agata Leońska-Duniec, Aleksandra Zarębska, Lauren K. Banting
Publikováno v:
Journal of science and medicine in sport. 18(1)
The A1470T polymorphism (rs1049434) in the monocarboxylate (lactate/pyruvate) transporter 1 gene (MCT1) has been suggested to influence athletic performance in the general population. We compared genotype distributions and allele frequencies of the M