Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Manabu, Igarashi"'
Publikováno v:
Viruses, Vol 13, Iss 5, p 913 (2021)
Filoviruses, including marburgviruses and ebolaviruses, have a single transmembrane glycoprotein (GP) that facilitates their entry into cells. During entry, GP needs to be cleaved by host proteases to expose the receptor-binding site that binds to th
Externí odkaz:
https://doaj.org/article/8214a536a4df4310bfb257174dc493b8
Autor:
Yoko Fujita-Fujiharu, Yukihiko Sugita, Yuki Takamatsu, Kazuya Houri, Manabu Igarashi, Yukiko Muramoto, Masahiro Nakano, Yugo Tsunoda, Ichiro Taniguchi, Stephan Becker, Takeshi Noda
Publikováno v:
Nature communications. 13(1)
The nucleoprotein (NP) of Marburg virus (MARV), a close relative of Ebola virus (EBOV), encapsidates the single-stranded, negative-sense viral genomic RNA (vRNA) to form the helical NP–RNA complex. The NP–RNA complex constitutes the core structur
Autor:
Takanari Hattori, Takeshi Saito, Hiroko Miyamoto, Masahiro Kajihara, Manabu Igarashi, Ayato Takada
Publikováno v:
Viruses; Volume 14; Issue 10; Pages: 2124
Human T-cell immunoglobulin mucin 1 (hTIM-1) is known to promote cellular entry of enveloped viruses. Previous studies suggested that the polymorphisms of hTIM-1 affected its function. Here, we analyzed single nucleotide variants (SNVs) of hTIM-1 to
Autor:
Katherine M Fuller, Erica Ollmann Saphire, Manabu Igarashi, Ayato Takada, Diptiben V. Parekh, Jacob C. Milligan
Publikováno v:
The Journal of Infectious Diseases. 219:415-419
Ebola virus infection causes severe disease in humans and represents a global health threat. Candidates for immunotherapeutics and vaccines have shown promise in clinical trials, although they are ineffective against other members of the Ebolavirus g
Autor:
Kosuke Okuya, Reiko Yoshida, Tatsunari Kondoh, Sakaitani Masahiro, Asuka Nanbo, Manabu Igarashi, Masahiro Kajihara, Mao Isono, Wakako Furuyama, Makoto Kuroda, Andrea Marzi, Heinz Feldmann, Ayato Takada, Hiroko Miyamoto, Rashid Manzoor
Publikováno v:
Antiviral Research. 183:104932
Ebolaviruses and marburgviruses, members of the family Filoviridae, are known to cause fatal diseases often associated with hemorrhagic fever. Recent outbreaks of Ebola virus disease in West African countries and the Democratic Republic of the Congo
Autor:
Hirofumi Sawa, Bernard M. Hang’ombe, Kimihito Ito, Hiroko Miyamoto, Katendi Changula, Chihiro Sugimoto, Makoto Kuroda, Keita Matsuno, Ichiro Nakamura, Manabu Igarashi, Junki Maruyama, Jackson Katampi, Yuka Thomas, Ayato Takada, Akihiro Ishii, Naganori Nao, Emiko Nakagawa, Heinz Feldmann, Aaron S. Mweene, Andrew Nambota, Mieko Muramatsu, Reiko Yoshida, Eri Nakayama, Masahiro Kajihara, Edgar Simulundu, Hirohito Ogawa, Ladslav Moonga, Boniface Namangala
Publikováno v:
Journal of Infectious Diseases. 212(2):S101-S108
Fruit bats are suspected to be a natural reservoir of filoviruses, including Ebola and Marburg viruses. Using an enzyme-linked immunosorbent assay based on the viral glycoprotein antigens, we detected filovirus-specific immunoglobulin G antibodies in
Autor:
Hiroko Miyamoto, Wakako Furuyama, Osamu Noyori, Ayato Takada, Asuka Nanbo, Heinz Feldmann, Junki Maruyama, Elaine Haddock, Manabu Igarashi, Reiko Yoshida, Andrea Marzi
Publikováno v:
Scientific Reports
During the latest outbreak of Ebola virus disease in West Africa, monoclonal antibody therapy (e.g., ZMapp) was utilized to treat patients. However, due to the antigenic differences among the five ebolavirus species, the current therapeutic monoclona
Autor:
Naganori Nao, Makoto Kuroda, Keita Matsuno, Ayato Takada, Daisuke Fujikura, Wakako Furuyama, Asako Shigeno, Manabu Igarashi, Rashid Manzoor, Reiko Yoshida, Masahiro Kajihara, Tatsunari Kondoh, Junki Maruyama, Hiroko Miyamoto
Publikováno v:
PLoS ONE
PLoS ONE, Vol 12, Iss 10, p e0186450 (2017)
PLoS ONE, Vol 12, Iss 10, p e0186450 (2017)
It has been proposed that some non-retroviral RNA virus genes are integrated into vertebrate genomes. Endogenous filovirus-like elements (EFLs) have been discovered in some mammalian genomes. However, their potential roles in ebolavirus infection are
Autor:
Mohamad Amin, Syafril Daulay, Reiko Yoshida, Eri Nakayama, Manabu Igarashi, Hiroko Miyamoto, Indi N. L. P. Dharmayanti, Chairul A. Nidom, Ayato Takada, Yoes Prijatna Dachlan, Mohamad Y. Alamudi, Reviany V. Nidom
Publikováno v:
PLoS ONE, Vol 7, Iss 7, p e40740 (2012)
PLoS ONE
PLoS ONE
Ebola virus (EBOV) and Marburg virus (MARV) belong to the family Filoviridae and cause severe hemorrhagic fever in humans and nonhuman primates. Despite the discovery of EBOV (Reston virus) in nonhuman primates and domestic pigs in the Philippines an
Autor:
Noriko Kishida, Hiroko Miyamoto, Eri Nakayama, Keita Matsuno, Kimihito Ito, Heinz Feldmann, Ayaka Yokoyama, Ayato Takada, Andrea Marzi, Masayuki Saijo, Manabu Igarashi
Publikováno v:
Clinical and vaccine immunology : CVI. 17(11)
Several enzyme-linked immunosorbent assays (ELISAs) for the detection of filovirus-specific antibodies have been developed. However, diagnostic methods to distinguish antibodies specific to the respective species of filoviruses, which provide the bas