Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Manabu, Igarashi"'
Autor:
Nodoka Kasajima, Keita Matsuno, Hiroko Miyamoto, Masahiro Kajihara, Manabu Igarashi, Ayato Takada
Publikováno v:
Viruses, Vol 13, Iss 11, p 2316 (2021)
Viral protein 35 (VP35) of Ebola virus (EBOV) is a multifunctional protein that mainly acts as a viral polymerase cofactor and an interferon antagonist. VP35 interacts with the viral nucleoprotein (NP) and double-stranded RNA for viral RNA transcript
Externí odkaz:
https://doaj.org/article/a0527a5bb6704eb7a1e2b8a7c96745d7
Autor:
Yoko Fujita-Fujiharu, Yukihiko Sugita, Yuki Takamatsu, Kazuya Houri, Manabu Igarashi, Yukiko Muramoto, Masahiro Nakano, Yugo Tsunoda, Ichiro Taniguchi, Stephan Becker, Takeshi Noda
Publikováno v:
Nature communications. 13(1)
The nucleoprotein (NP) of Marburg virus (MARV), a close relative of Ebola virus (EBOV), encapsidates the single-stranded, negative-sense viral genomic RNA (vRNA) to form the helical NP–RNA complex. The NP–RNA complex constitutes the core structur
Autor:
Masahiro Nakano, Yoko Fujita-Fujiharu, Yugo Tsunoda, Yukiko Muramoto, Kazuya Houri, Yukihiko Sugita, Yuki Takamatsu, Stephan Becker, Takeshi Noda, Manabu Igarashi
The nucleoprotein (NP) of Marburg virus (MARV), a close relative of Ebola virus (EBOV), encapsidates the single-stranded, negative-sense viral genomic RNA (vRNA) to form the helical NP-RNA complex. The NP-RNA complex serves as a scaffold for the asse
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::606a8beffef02b46d6ef634bd944bf17
https://doi.org/10.1101/2021.07.13.452116
https://doi.org/10.1101/2021.07.13.452116
Autor:
Katherine M Fuller, Erica Ollmann Saphire, Manabu Igarashi, Ayato Takada, Diptiben V. Parekh, Jacob C. Milligan
Publikováno v:
The Journal of Infectious Diseases. 219:415-419
Ebola virus infection causes severe disease in humans and represents a global health threat. Candidates for immunotherapeutics and vaccines have shown promise in clinical trials, although they are ineffective against other members of the Ebolavirus g
Autor:
Takeshi Saito, Yoshihiro Takadate, Rashid Manzoor, Hiroko Miyamoto, Manabu Igarashi, Ayato Takada, Yurie Kida, Hirohito Ogawa, Junki Maruyama, Masahiro Kajihara, Tatsunari Kondoh
Publikováno v:
Microorganisms, Vol 8, Iss 1530, p 1530 (2020)
Microorganisms
Volume 8
Issue 10
Microorganisms
Volume 8
Issue 10
Lloviu virus (LLOV), a bat-derived filovirus that is phylogenetically distinct from human pathogenic filoviruses such as Ebola virus (EBOV) and Marburg virus (MARV), was discovered in Europe. However, since infectious LLOV has never been isolated, th
Publikováno v:
Viruses
Volume 13
Issue 5
Viruses, Vol 13, Iss 913, p 913 (2021)
Volume 13
Issue 5
Viruses, Vol 13, Iss 913, p 913 (2021)
Filoviruses, including marburgviruses and ebolaviruses, have a single transmembrane glycoprotein (GP) that facilitates their entry into cells. During entry, GP needs to be cleaved by host proteases to expose the receptor-binding site that binds to th
Autor:
Kosuke Okuya, Reiko Yoshida, Tatsunari Kondoh, Sakaitani Masahiro, Asuka Nanbo, Manabu Igarashi, Masahiro Kajihara, Mao Isono, Wakako Furuyama, Makoto Kuroda, Andrea Marzi, Heinz Feldmann, Ayato Takada, Hiroko Miyamoto, Rashid Manzoor
Publikováno v:
Antiviral Research. 183:104932
Ebolaviruses and marburgviruses, members of the family Filoviridae, are known to cause fatal diseases often associated with hemorrhagic fever. Recent outbreaks of Ebola virus disease in West African countries and the Democratic Republic of the Congo
Autor:
Hirofumi Sawa, Bernard M. Hang’ombe, Kimihito Ito, Hiroko Miyamoto, Katendi Changula, Chihiro Sugimoto, Makoto Kuroda, Keita Matsuno, Ichiro Nakamura, Manabu Igarashi, Junki Maruyama, Jackson Katampi, Yuka Thomas, Ayato Takada, Akihiro Ishii, Naganori Nao, Emiko Nakagawa, Heinz Feldmann, Aaron S. Mweene, Andrew Nambota, Mieko Muramatsu, Reiko Yoshida, Eri Nakayama, Masahiro Kajihara, Edgar Simulundu, Hirohito Ogawa, Ladslav Moonga, Boniface Namangala
Publikováno v:
Journal of Infectious Diseases. 212(2):S101-S108
Fruit bats are suspected to be a natural reservoir of filoviruses, including Ebola and Marburg viruses. Using an enzyme-linked immunosorbent assay based on the viral glycoprotein antigens, we detected filovirus-specific immunoglobulin G antibodies in
Autor:
Andrea Marzi, Reiko Yoshida, Masahiro Kajihara, Hiroko Miyamoto, Alexander N. Freiberg, Manabu Igarashi, Yoshihiro Takadate, Hirohito Ogawa, Terence E. Hill, Wakako Furuyama, Tatsunari Kondoh, Heinz Feldmann, Ayato Takada, Masahiro Sato, Rashid Manzoor, Junki Maruyama
Publikováno v:
Cell Reports, Vol 30, Iss 2, Pp 308-319.e5 (2020)
Summary: Fruit bats are suspected to be natural hosts of filoviruses, including Ebola virus (EBOV) and Marburg virus (MARV). Interestingly, however, previous studies suggest that these viruses have different tropisms depending on the bat species. Her
Autor:
Makoto Kuroda, Asuka Nanbo, Andrea Marzi, Manabu Igarashi, Aaron B. Carmody, Junki Maruyama, Wakako Furuyama, Reiko Yoshida, Ayato Takada, Heinz Feldmann, Hiroko Miyamoto, Rashid Manzoor
Publikováno v:
PLoS Pathogens
PLoS Pathogens, Vol 12, Iss 12, p e1006139 (2016)
PLoS Pathogens, Vol 12, Iss 12, p e1006139 (2016)
Antibody-dependent enhancement (ADE) of Ebola virus (EBOV) infection has been demonstrated in vitro, raising concerns about the detrimental potential of some anti-EBOV antibodies. ADE has been described for many viruses and mostly depends on the cros