Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Kuo-Yun Tseng"'
Publikováno v:
International journal of antimicrobial agents. 45(6)
The cph1/cph1 efg1/efg1 double mutant in Candida albicans is defective in filamentous growth and is avirulent in a mouse model. We previously reported that Efg1p but not Cph1p is involved in drug resistance by negatively regulating ERG3 in C. albican
Autor:
Kuo-Yun Tseng, Ci-Hong Liou, Chia-Geun Chen, Hsin-I Shih, Yun-Liang Yang, Hsiu-Jung Lo, Chih-Chao Lin
Publikováno v:
Fungal genetics and biology : FGB. 46(9)
Overexpression of MDR1 efflux pump is a major mechanism contributing to drug resistance in Candida albicans, the most common human fungal pathogen. To elucidate the regulatory pathway of drug resistance, we have identified a negative regulator of MDR
Autor:
Yun-Liang Yang, Karen J. Ouyang, Hsin Wang, Kuo-Yun Tseng, Jang-Shiun Wang, Chia-Geun Chen, Chin-Jung Wu, Hsiu-Jung Lo
Publikováno v:
Journal of medical microbiology. 55(Pt 10)
CaNdt80p, theCandida albicanshomologue of theSaccharomyces cerevisiaetranscription factor ScNdt80p, has been identified as a positive regulator ofCDR1, which encodes an efflux pump involved in drug resistance inC. albicans. To investigate the involve