Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Maki Iwago"'
Autor:
Kazuhiko Yumoto, Koji Murakami, Shigeki Seto, Reiko Terasawa, Yasushi Kohno, Kevin R. Shreder, Aya Iwane, Yoshikazu Asahina, Maki Iwago, Kyoko Okada
Publikováno v:
Bioorganicmedicinal chemistry. 20(3)
The design, synthesis, and evaluation of 6-6-7 tricyclic quinolones containing the strained spirocycle moiety aiming at the GSK-3β inhibitor were described. Among the synthesized compounds, 44, having a cyclobutane ring on a spirocycle, showed excel
Autor:
Yasushi Kohno, Koji Murakami, Shigeki Seto, Maki Iwago, Kyoko Okada, Shigeki Isogai, Takehiro Shinozaki, Yoshiaki Kitamura, Koichi Kiyota
Publikováno v:
Journal of medicinal chemistry. 53(13)
A series of novel 2,4,6-trisubstitutedpyrimidine-5-carboxylic acid derivatives were designed and synthesized with the intent of producing a peroxisome proliferator-activated receptor gamma (PPARgamma) partial agonist for antidiabetic agents. A pharma