Zobrazeno 1 - 10
of 75
pro vyhledávání: '"Hiroyuki Watanabe"'
Publikováno v:
Chemical and Pharmaceutical Bulletin. 71:234-239
Publikováno v:
Molecular Pharmaceutics. 19:2832-2839
Autor:
Shimpei Iikuni, Yuta Tarumizu, Shohei Tsuchihashi, Takaki Ohara, Hiroyuki Watanabe, Masahiro Ono
Publikováno v:
Molecular Pharmaceutics. 19:2725-2736
Publikováno v:
Journal of Labelled Compounds and Radiopharmaceuticals.
Publikováno v:
Molecular Pharmaceutics. 19:1019-1027
Autor:
Yusuke Higaki, Hiroaki Ichikawa, Yuta Tarumizu, Shimpei Iikuni, Masahiro Ono, Hiroyuki Watanabe, Kazuma Nakashima
Publikováno v:
Journal of Medicinal Chemistry. 64:13429-13438
225Ac-based radiotheranostics targeting prostate-specific membrane antigen (PSMA) has induced impressive responses in patients with metastatic castration-resistant prostate cancer. To enhance the therapeutic effects of radioligands labeled with 225Ac
Publikováno v:
ACS medicinal chemistry letters. 13(10)
We have reported that the chelator-based clickable radiotheranostic platform, ADIBO-DOTADG-ALB (ADA), has favorable properties as a radiotheranostic platform for low-molecular-weight ligands. In this study, we evaluated the applicability of ADA to mo
Publikováno v:
ACS medicinal chemistry letters. 13(10)
Synucleinopathies are characterized by the deposition of α-synuclein (α-syn) aggregates before the onset of clinical symptoms. Therefore
Autor:
Hiroyuki Watanabe, Yoichi Shimizu, Shimpei Iikuni, Yuji Nakamoto, Yuta Tarumizu, Sho Kaide, Masahiro Ono
Publikováno v:
ACS Med Chem Lett
[Image: see text] Noninvasive imaging of tau aggregates with a positron emission tomography (PET) tracer is useful for the diagnosis and staging of Alzheimer’s disease (AD). Recently, we found that benzimidazopyridine (BIP) is an attractive scaffol
Autor:
Shimpei Iikuni, Yoichi Shimizu, Hiroyuki Watanabe, Kiyoshiro Kawano, Kaori Togashi, Yuji Nakamoto, Masahiro Ono
Publikováno v:
Molecular Pharmaceutics. 17:1293-1299
The deposition of islet amyloid is associated with β-cell mass dysfunction in type 2 diabetes mellitus (T2DM). Since the amylin aggregate is the main component of islet amyloid, in vivo imaging of amylin may be useful for diagnosis and elucidation o