Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Yasuo Urata"'
Autor:
Jeong Heo, Ja-Der Liang, Chang Won Kim, Hyun Young Woo, I-Lun Shih, Tung-Hung Su, Zhong-Zhe Lin, So Young Yoo, Stanley Chang, Yasuo Urata, Pei-Jer Chen
Publikováno v:
Molecular Therapy.
Autor:
Nobuhiko Kanaya, Tomoko Tsumura, Ryoma Sugimoto, Toshiyoshi Fujiwara, Satoru Kikuchi, Masashi Hashimoto, Yasuo Urata, Hiroshi Tazawa, Kento Kumon, Masahiko Nishizaki, Shinji Kuroda, Yuki Hamada, Yoshihiko Kakiuchi, Chiaki Yagi, Shunsuke Kagawa
Publikováno v:
Mol Ther
Extracellular vesicles (EVs) play important roles in various intercellular communication processes. The abscopal effect is an interesting phenomenon in cancer treatment, in which immune activation is generally considered a main factor. We previously
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::694e1e8c95f8e15ca5b3ea376ea13ad5
https://europepmc.org/articles/PMC8530926/
https://europepmc.org/articles/PMC8530926/
Autor:
Yasuo Urata, Satoru Kikuchi, Masashi Hashimoto, Nobuhiko Kanaya, Hiroyuki Mizuguchi, Kento Kumon, Shunsuke Kagawa, Tomoko Tsumura, Katsuyuki Aoyama, Tetsushi Kubota, Yoshihiko Kakiuchi, Masahiko Nishizaki, Shinji Kuroda, Toshiyoshi Fujiwara, Hiroshi Tazawa, Toshiaki Morihiro
Publikováno v:
Mol Ther
The clinical benefit of monotherapy involving immune checkpoint inhibitors (ICIs) such as anti-programmed death-1 antibody (PD-1 Ab) is limited to small populations. We previously developed a telomerase-specific oncolytic adenovirus, Telomelysin (OBP
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3f7e840e5e7e2a07a49da0c071434c45
https://europepmc.org/articles/PMC7054725/
https://europepmc.org/articles/PMC7054725/
Autor:
Toshiyoshi Fujiwara, Hiroshi Tazawa, Michael Bouvet, Shinji Miwa, Hiroyuki Kishimoto, Yasuo Urata, Robert M. Hoffman, Shuya Yano, Mako Yamamoto, Shunsuke Kagawa, Yukihiko Hiroshima, Makoto Toneri
Publikováno v:
Molecular therapy : the journal of the American Society of Gene Therapy, vol 23, iss 7
Fluorescence-guided surgery (FGS) of cancer is an area of intense current interest. However, although benefits have been demonstrated with FGS, curative strategies need to be developed. Glioblastoma multiforme (GBM) is one of the most invasive of can
Autor:
Masahiko Nishizaki, Shinji Kuroda, Takeshi Nagasaka, Yuuri Hashimoto, Yasuo Urata, Yasuhiro Shirakawa, Satoru Kikuchi, Hiroshi Tazawa, Robert M. Hoffman, Shunsuke Kagawa, Hiroyuki Kishimoto, Toshiyoshi Fujiwara
Publikováno v:
Molecular Therapy. 23(3):501-509
Currently, early gastrointestinal cancers are treated endoscopically, as long as there are no lymph node metastases. However, once a gastrointestinal cancer invades the submucosal layer, the lymph node metastatic rate rises to higher than 10%. Theref
Autor:
James M. Burke, Beena O. Pappen, Salina Chen, Daiju Ichimaru, Neil Senzer, Ned Adams, Anagha P. Phadke, Yasuo Urata, Alex W. Tong, Cynthia Bedell, John Nemunaitis, Yu An Zhang, Toshiyoshi Fujiwara, Phillip B. Maples, Michael Nemunaitis
Publikováno v:
Molecular therapy : the journal of the American Society of Gene Therapy. 18(2)
A phase I clinical trial was conducted to determine the clinical safety of Telomelysin, a human telomerase reverse transcriptase (hTERT) promoter driven modified oncolytic adenovirus, in patients with advanced solid tumors. A single intratumoral inje
Publikováno v:
Current cancer drug targets. 7(2)
Replication-selective tumor-specific viruses present a novel approach for treatment of neoplastic disease. These vectors are designed to induce virus-mediated lysis of tumor cells after selective viral propagation within the tumor. For targeting canc
Autor:
Yuuri Hashimoto, Toshiyoshi Fujiwara, Noriaki Tanaka, Shunsuke Kagawa, Yasuo Urata, Katsuyuki Nagai, Yuichi Watanabe, Hitoshi Kawamura, Toru Kojima
Publikováno v:
Molecular Therapy. 13
Malignant mesothelioma is an extraordinarily challenging disease to treat; however, locoregional virotherapy may be applicable for this aggressive disease because of the accessibility by intrapleural and/or intratumoral virus delivery. We previously
Autor:
Noriaki Tanaka, Masayoshi Hioki, Hiroyuki Kishimoto, Yasuo Urata, Yoshihiro Ikeda, Yuichi Watanabe, Fuminori Teraishi, Toshiyoshi Fujiwara, Toru Kojima, Ryo Sakai, Shunsuke Kagawa
Publikováno v:
Molecular Therapy. 13
Currently available methods for detection of tumors in vivo such as X-ray, computed tomography, ultrasonography, and magnetic resonance imaging are noninvasive and are well studied; the images, however, are not specific for tumors. Direct optical ima
Autor:
Toshiya Fujiwara, Yoshiko Shirakiya, Yoshihiro Ikeda, Yasuo Urata, Toru Kojima, Yuuri Hashimoto, Ryo Sakai, Futoshi Uno, Shunsuke Kagawa, Masayoshi Hioki, Yuichi Watanabe, Fuminori Teraishi
Publikováno v:
Molecular Therapy. 13:S248-S249
Cancer gene therapy and oncolytic virotherapy have been studied extensively. However, the clinical application is hampered by its weak anticancer activity. We constructed a replicating adenovirus (OBP-301, Telomelysin), in which the human telomerase