Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Renee Whan"'
Autor:
Eh Hau Pan, Brian S. Hawkett, Renee Whan, Nicole S. Bryce, Nicole W. S. Fong, Binh T. T. Pham, Trevor W. Hambley, Nirmesh Jain
Publikováno v:
Biomater. Sci.. 1:1260-1272
Diffusion of active cytotoxic agents throughout an entire solid tumour is a particular challenge to successful drug delivery. Here we show the simple and robust generation of non-toxic, 10-15 nm superparamagnetic iron oxide nanoparticles (SPIONs) tha
Autor:
Alexander Macmillan, Renee Whan, Sharon M. Sagnella, Volga Bulmus, Thomas P. Davis, Maria Kavallaris, Sema Sevimli
Previously synthesized poly(methacrylic acid-co-cholesteryl methacrylate) P(MAA-co-CMA) copolymers were examined as potential drug delivery vehicles. P(MAA-co-CMA) copolymers were fluorescently labelled and imaged in SHEP and HepG2 cells. To understa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::43eedf97a594a826b26b6ec4ef5a5f7e
http://hdl.handle.net/11147/5566
http://hdl.handle.net/11147/5566
Autor:
Sophie Laurent, Hien T. T. Duong, Alexandre MacMillan, Robert N. Muller, Thomas P. Davis, Renee Whan, Yang Li, Jinming Hu, Cyrille Boyer, Luce Vander Elst, Andrew B. Lowe
Publikováno v:
Advanced healthcare materials. 4(1)
Dual-functional star polymers (diameters 15 nm) are synthesized producing nanoparticles with excellent colloidal stability in both water and serum. The nanoparticles are built with aldehyde groups in the core and activated esters in the arms. The dif
Autor:
Thomas P. Davis, Cyrille Boyer, Hien T. T. Duong, Alexander Macmillan, Maria Kavallaris, Joshua A. McCarroll, Renee Whan, Sharon M. Sagnella
Publikováno v:
Biomacromolecules. 15(1)
Drug delivery systems with improved tumor penetration are valuable assets as anticancer agents. A dextran-based nanocarrier system with aldehyde functionalities capable of forming an acid labile linkage with the chemotherapy drug doxorubicin was deve
Autor:
Felicity Hughes, Thomas P. Davis, Hien T. T. Duong, James M. Hook, Maria Kavallaris, Renee Whan, Cyrille Boyer, Alexander Macmillan, Sharon M. Sagnella
Publikováno v:
Molecular pharmaceutics. 9(11)
Conferring biodegradability to nanoparticles is vitally important when nanomedicine applications are being targeted, as this prevents potential problems with bioaccumulation of byproducts after delivery. In this work, dextran has been modified (and r