Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Chunai Gong"'
Autor:
Chunai Gong, Jing Tian, Zhuo Wang, Yuan Gao, Xin Wu, Xueying Ding, Lei Qiang, Guorui Li, Zhimin Han, Yongfang Yuan, Shen Gao
Publikováno v:
Journal of Nanobiotechnology, Vol 17, Iss 1, Pp 1-18 (2019)
Abstract Exosomes (Exo) hold great promise as endogenous nanocarriers that can deliver biological information between cells. However, Exo are limited in terms of their abilities to target specific recipient cell types. We developed a strategy to isol
Externí odkaz:
https://doaj.org/article/de1e87f3c57a457a8f8bd6d6cde628c3
Publikováno v:
Journal of Biomaterials Applications. 36:1317-1331
Resistance to apoptosis is a key mechanism underlying how cancer cells evade tumor therapy. Autophagy can prevent anticancer drug-induced apoptosis and promote tumor resistance. The purpose of this study was to improve the sensitivity and efficacy of
Autor:
Yuan Gao, Chuling Hu, Lijuan Zhang, Li Yan, Qingming Xia, Huiling Guo, Shen Gao, Chunai Gong, Gu Fenfen, Zhuo Wang
Publikováno v:
Nanomedicine: Nanotechnology, Biology and Medicine. 14:1973-1985
Exosomes have emerged as a promising drug carrier with low immunogenicity, high biocompatibility and delivery efficiency. Here in, we isolated exosomes from A33-positive LIM1215 cells (A33-Exo) and loaded them with doxorubicin (Dox). Furthermore, we
Apoptosis tolerance is an important mechanism of tumor resistance in tumor therapy. Autophagy can prevent apoptosis induced by antitumor drugs and promote tumor resistance. The purpose of the presentn study was to improve the sensitivity of chemother
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::176a0eebf2a33a0982a7e34b56c2b4fd
https://doi.org/10.21203/rs.3.rs-128663/v1
https://doi.org/10.21203/rs.3.rs-128663/v1
Autor:
Chunai Gong, Yan Wu, Lu Han, Yujie Wang, Rong Wang, Xiaoyan Yu, Yongfang Yuan, Benming You, Shen Gao
Publikováno v:
Journal of Nanobiotechnology
Journal of Nanobiotechnology, Vol 18, Iss 1, Pp 1-17 (2020)
Journal of Nanobiotechnology, Vol 18, Iss 1, Pp 1-17 (2020)
Cell membrane- covered drug-delivery nanoplatforms have been garnering attention because of their enhanced bio-interfacing capabilities that originate from source cells. In this top-down technique, nanoparticles (NPs) are covered by various membrane
Autor:
Tai Zongguang, Yuan Gao, Jiyong Liu, Zheng Cai, Shen Gao, Guorui Li, Wenjun Jiang, Lei Qiang, Chunai Gong
Publikováno v:
Journal of Nanobiotechnology, Vol 17, Iss 1, Pp 1-15 (2019)
Journal of Nanobiotechnology
Journal of Nanobiotechnology
Background Macrophages with tumor-tropic migratory properties can serve as a cellular carrier to enhance the efficacy of anti neoplastic agents. However, limited drug loading (DL) and insufficient drug release at the tumor site remain the main obstac
Autor:
Xin Wu, Xueying Ding, Chunai Gong, Guorui Li, Shen Gao, Zhuo Wang, Zhimin Han, Tian Jing, Lei Qiang, Yuan Gao, Yongfang Yuan
Publikováno v:
Journal of Nanobiotechnology
Journal of Nanobiotechnology, Vol 17, Iss 1, Pp 1-18 (2019)
Journal of Nanobiotechnology, Vol 17, Iss 1, Pp 1-18 (2019)
Exosomes (Exo) hold great promise as endogenous nanocarriers that can deliver biological information between cells. However, Exo are limited in terms of their abilities to target specific recipient cell types. We developed a strategy to isolate Exo e
Autor:
Qingming Xia, Chunai Gong, Gu Fenfen, Tai Zongguang, Yuan Gao, Chuling Hu, Chong Yao, Shen Gao
Publikováno v:
Oncotarget
Cationic peptides as a non-viral gene vector have become a hotspot of research because of their high transfection efficcacy and safety. Based on our previous study, we synthesized a cationic reduction-responsive vector based on disulfide cross-linked