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pro vyhledávání: '"P J, Trainer"'
Publikováno v:
The Journal of clinical endocrinology and metabolism. 86(7)
Pegvisomant is a GH receptor antagonist and highly efficacious new treatment for acromegaly. The two isoenzymes of 11beta-hydroxysteroid dehydrogenase are responsible for the interconversion of cortisol and its inactive metabolite cortisone. We demon
Publikováno v:
Clinical endocrinology. 48(4)
Bone metabolism is an important target for GH replacement therapy. However, in adults, treatment periods exceeding 12 months are required for a positive effect of GH on bone mineral density. Thus, to detect an early effect of GH on bone, markers of b