Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Michael R Migden"'
Autor:
Reinhard Dummer, Michael R. Migden, Alexander Guminski, Nicholas Squittieri, John T. Lear, Liang Joo Leow
Publikováno v:
Journal of the American Academy of Dermatology. 84(4)
Autor:
Ruth Plummer, Martin Kaatz, Alexander Guminski, Patrick Combemale, Karl D. Lewis, Ragini R. Kudchadkar, Manisha Mone, Dalila Sellami, Jocelyn Zhou, Carmen Loquai, Luc Dirix, Anne Lynn S. Chang, Ralf Gutzmer, John T. Lear, Tingting Yi, Michael R. Migden, Reinhard Dummer, Alexandros Stratigos, Uwe Trefzer, Henry Castro
Publikováno v:
Journal of the European Academy of Dermatology and Venereology
Background Patients with locally advanced basal cell carcinoma (laBCC) or metastatic BCC (mBCC), two difficult-to-treat populations, have had limited treatment options. Sonidegib, a hedgehog pathway inhibitor (HPI), was approved in laBCC based on res
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c2c71a42ca781cb5725f0ad8c828de1c
https://www.zora.uzh.ch/id/eprint/143585/
https://www.zora.uzh.ch/id/eprint/143585/
Autor:
Ralf Gutzmer, Tingting Yi, Alexander Guminski, Hans Joachim Schulze, Alexander J. Stratigos, Carmen Loquai, Patrick Combemale, Anne Lynn S. Chang, R. Herd, Ragini R. Kudchadkar, Ruth Plummer, Dalila Sellami, Frank Cornelis, Luc Dirix, Michael R. Migden, Reinhard Dummer, Sven Gogov, Karl D. Lewis, John T. Lear, Celine Pallaud, Manisha Mone, Martin Kaatz, Uwe Trefzer
Summary Background Patients with advanced basal cell carcinoma have limited treatment options. Hedgehog pathway signalling is aberrantly activated in around 95% of tumours. We assessed the antitumour activity of sonidegib, a Hedgehog signalling inhib
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0a068ac7f39ea8f9f41d63de9159e17b
https://doi.org/10.5167/uzh-113018
https://doi.org/10.5167/uzh-113018
Autor:
Michael R. Migden, Anne Lynn S. Chang, Karl D. Lewis, Celine Pallaud, Luc Dirix, Frank Cornelis, Manisha Mone, Reinhard Dummer, Sven Gogov, John T. Lear, Martin Kaatz, Ruth Plummer, Patrick Combemale, Uwe Trefzer, Ralf Gutzmer, Alexander Guminski, Carmen Loquai, Dalila Sellami, Alexander J. Stratigos, Ragini R. Kudchadkar, Tingting Yi, R. Herd, Hans Joachim Schulze
Publikováno v:
Journal of the American academy of dermatology, Vol. 75, no.1, p. 113-125.e5 (2016)
Background The hedgehog pathway inhibitor sonidegib demonstrated meaningful tumor shrinkage in more than 90% of patients with locally advanced basal cell carcinoma (BCC) or metastatic BCC in the BCC Outcomes with LDE225 Treatment study. Objective Thi