Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Larisa V. Gubareva"'
Autor:
Jianzhu Chen, Alexander M. Klibanov, Larisa V. Gubareva, Terrence M. Tumpey, Luis Álvarez de Cienfuegos, Alisha K. Weight, Jayanta Haldar
Publikováno v:
PMC
Effects of the commercial drug zanamivir (Relenza™) covalently attached to poly-l-glutamine on the infectivity of influenza A viruses are examined using the plaque reduction assay and binding affinity to viral neuraminidase (NA). These multivalent
Autor:
Michael W. Shaw, Rebecca Garten, Larisa V. Gubareva, Alexander Klimov, Margaret Okomo-Adhiambo, Vasiliy P. Mishin, Tiffany G. Sheu, Varough M. Deyde, Ha T. Nguyen, A. Angelica Trujillo, Alicia M. Fry, Katrina Sleeman
Publikováno v:
Antiviral Therapy. 15:1151-1159
Background Antiviral drugs are an important option for managing infections caused by influenza viruses. This study assessed the drug susceptibility of 2009 pandemic influenza A (H1N1) viruses collected globally between April 2009 and January 2010. Me
Autor:
Vasiliy P. Mishin, Alexander Klimov, Varough M. Deyde, Yousuke Furuta, Larisa V. Gubareva, Katrina Sleeman
Favipiravir (T-705) has previously been shown to have a potent antiviral effect against influenza virus and some other RNA viruses in both cell culture and in animal models. Currently, favipiravir is undergoing clinical evaluation for the treatment o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8c9a475c322122c28448327c229c7d7e
https://europepmc.org/articles/PMC2876376/
https://europepmc.org/articles/PMC2876376/
Autor:
Kevin R. Steffy, Dale J. Kempf, Akhteruzzaman Molla, Debra Montgomery, Robert J Carrick, Warren M. Kati, Keith F. McDaniel, Frederick G. Hayden, William E. Kohlbrenner, Clarence J. Maring, Larisa V. Gubareva
A-315675 is a novel, pyrrolidine-based compound that was evaluated in this study for its ability to inhibit A and B strain influenza virus neuraminidases in enzyme assays and influenza virus replication in cell culture. A-315675 effectively inhibited
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4f526c4b36090030e3aaf5593a57375b
https://europepmc.org/articles/PMC127111/
https://europepmc.org/articles/PMC127111/
Publikováno v:
The Journal of infectious diseases. 172(1)
A Vero cell line was investigated as a suitable host system for primary isolation and cultivation of influenza A viruses. The efficiency of primary isolation for currently circulating (H3N2) strains was similar in Vero and MDCK cells. Of 72 egg-adapt