Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Robert J. Duronio"'
Publikováno v:
Genetics
Replication initiation in eukaryotic cells occurs asynchronously throughout S phase, yielding early and late replicating regions of the genome, a process known as replication timing (RT). RT changes during development to ensure accurate genome duplic
Autor:
Alexander Emelyanov, Evgeniya N. Andreyeva, Arthur I. Skoultchi, Elena Vershilova, Markus Nevil, Michael-Christopher Keogh, Christina A. Hill, Dmitry V. Fyodorov, Robert J. Duronio, Lu Sun
Asynchronous replication of chromosome domains during S phase is essential for eukaryotic genome function, but the mechanisms establishing which domains replicate early versus late in different cell types remain incompletely understood. Drosophila SN
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0e06d635d28943b62e85fc61a2de14d1
https://doi.org/10.1101/2021.10.02.462895
https://doi.org/10.1101/2021.10.02.462895
Autor:
David M. MacAlpine, Robin L. Armstrong, Taylor J.R. Penke, Robert J. Duronio, Daniel J. McKay, A. Gregory Matera, Brian D. Strahl
Publikováno v:
Genome Research. 28:1688-1700
Chromatin structure has emerged as a key contributor to spatial and temporal control over the initiation of DNA replication. However, despite genome-wide correlations between early replication of gene-rich, accessible euchromatin and late replication
Autor:
Robin L. Armstrong, Taylor J.R. Penke, Daniel J. McKay, Robert J. Duronio, Brian D. Strahl, Samuel K Chao, A. Gregory Matera, Gabrielle M Gentile
Publikováno v:
Genes
Volume 10
Issue 2
Genes, Vol 10, Iss 2, p 93 (2019)
Volume 10
Issue 2
Genes, Vol 10, Iss 2, p 93 (2019)
Chromatin structure and its organization contributes to the proper regulation and timing of DNA replication. Yet, the precise mechanism by which chromatin contributes to DNA replication remains incompletely understood. This is particularly true for c
Autor:
Brian D. Strahl, Christopher M. Uyehara, Daniel J. McKay, Mary Leatham-Jensen, A. Gregory Matera, Robert J. Duronio
Publikováno v:
PLoS Genetics
PLoS Genetics, Vol 15, Iss 1, p e1007932 (2019)
PLoS Genetics, Vol 15, Iss 1, p e1007932 (2019)
Proper determination of cell fates depends on epigenetic information that is used to preserve memory of decisions made earlier in development. Post-translational modification of histone residues is thought to be a central means by which epigenetic in
Autor:
Robert J. Duronio
Publikováno v:
Genes & Development. 26:746-750
The duration of S phase in early embryos is often short, and then increases as development proceeds because of the appearance of late-replicating regions of the genome. In the April 1, 2012, issue of Genes & Development, Farrell and colleagues (pp. 7
Publikováno v:
Nucleic Acids Research
The local chromatin environment is a key regulator of DNA-templated processes including transcription, DNA replication, and DNA repair. The methylation state of lysine 20 on histone H4 (H4K20) has been linked to cell cycle progression, origin recogni
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a418db68fb927d976bfb696692e82069
Publikováno v:
Molecular Biology of the Cell
Previous studies have shown that Cdt1 overexpression in cultured cells can trigger re-replication, but not whether CRL4Cdt2-triggered destruction of Cdt1 is required for normal mitotic cell cycle progression in vivo. We demonstrate that PIP box–med
Autor:
Robert J. Duronio, Aida Flor A. de la Cruz, Bruce A. Edgar, Vuong Tran, Tânia Reis, Shusaku Shibutani, William J. Turbyfill
Publikováno v:
Developmental Cell. 15(6):890-900
Summary E2F transcription factors are key regulators of cell proliferation that are inhibited by pRb family tumor suppressors. pRb-independent modes of E2F inhibition have also been described, but their contribution to animal development and tumor su
Autor:
Brandon D. Burch, William F. Marzluff, Robert J. Duronio, Eric J. Wagner, Harmony R. Salzler, Ashley C. Godfrey
Publikováno v:
Molecular Cell. 28:692-699
Summary Metazoan replication-dependent histone mRNAs are not polyadenylated and instead end in a conserved stem loop that is the cis element responsible for coordinate posttranscriptional regulation of these mRNAs. Using biochemical approaches, only