Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Tsukasa Shimauchi"'
Autor:
Junichi Omura, Sandra Breuils-Bonnet, Eve Tremblay, Alice Bourgeois, Steeve Provencher, Yann Grobs, Tsukasa Shimauchi, Geraldine Vitry, Wen-Hui Wu, Victoria Toro, Mark Orcholski, Roxane Paulin, Sandra Martineau, Valérie Nadeau, Sébastien Bonnet, Pasquale Ferraro, Charlotte Romanet, François Potus, Olivier Boucherat
Publikováno v:
Thorax. 77:247-258
BackgroundIdiopathic pulmonary fibrosis (IPF) is a chronic lung disease characterised by exuberant tissue remodelling and associated with high unmet medical needs. Outcomes are even worse when IPF results in secondary pulmonary hypertension (PH). Imp
Autor:
Roxane Paulin, Steeve Provencher, Sandra Breuils Bonnet, Eve Tremblay, Valérie Nadeau, François Potus, Junichi Omura, Sébastien Bonnet, Olivier Boucherat, Tsukasa Shimauchi, Yann Grobs
Publikováno v:
Circulation. 142
Background: Right ventricular failure (RVF) is a poor prognostic factor for pulmonary arterial hypertension (PAH) patients. Inflammation, oxidative stress-induced DNA damage, and glycolysis are key RVF-driven pathways triggering cardiomyocytes (CM) d
Autor:
Sarah-Eve Lemay, Roxane Paulin, Alice Bourgeois, Eve Tremblay, Renée Paradis, Geraldine Vitry, Karima Habbout, Marie-Claude Lampron, Olivier Boucherat, Sandra Breuils-Bonnet, Florence Roux-Dalvai, Yann Grobs, Charifa Awada, Tsukasa Shimauchi, Mark Orcholski, Valérie Nadeau, Steeve Provencher, François Potus, Sébastien Bonnet
Publikováno v:
American Journal of Respiratory and Critical Care Medicine
Rationale: Pulmonary arterial hypertension (PAH) is a life-threatening condition characterized by abnormally elevated pulmonary pressures and right ventricular failure. Excessive proliferation and resistance to apoptosis of pulmonary artery smooth mu