Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Knight, Laura"'
Autor:
Parkes EE; Patrick G Johnston Centre for Cancer Research, Queen's University Belfast, 97 Lisburn Road, Belfast, BT9 7AE, UK.; Belfast Health and Social Care Trust, Belfast City Hospital, Lisburn Road, Belfast, BT9 7AB, UK.; Department of Oncology, Medical Sciences Division, University of Oxford, Oxford, UK., Savage KI; Patrick G Johnston Centre for Cancer Research, Queen's University Belfast, 97 Lisburn Road, Belfast, BT9 7AE, UK., Lioe T; Belfast Health and Social Care Trust, Belfast City Hospital, Lisburn Road, Belfast, BT9 7AB, UK., Boyd C; Belfast Health and Social Care Trust, Belfast City Hospital, Lisburn Road, Belfast, BT9 7AB, UK., Halliday S; Patrick G Johnston Centre for Cancer Research, Queen's University Belfast, 97 Lisburn Road, Belfast, BT9 7AE, UK., Walker SM; Almac Diagnostic Services, Almac Group, 19 Seagoe Industrial Estate, Craigavon, BT63 5QD, UK., Lowry K; Belfast Health and Social Care Trust, Belfast City Hospital, Lisburn Road, Belfast, BT9 7AB, UK., Knight L; Almac Diagnostic Services, Almac Group, 19 Seagoe Industrial Estate, Craigavon, BT63 5QD, UK., Buckley NE; School of Pharmacy, Queen's University Belfast, 97 Lisburn Road, Belfast, BT9 7AE, UK., Grogan A; Almac Diagnostic Services, Almac Group, 19 Seagoe Industrial Estate, Craigavon, BT63 5QD, UK., Logan GE; Almac Diagnostic Services, Almac Group, 19 Seagoe Industrial Estate, Craigavon, BT63 5QD, UK., Clayton A; Belfast Health and Social Care Trust, Belfast City Hospital, Lisburn Road, Belfast, BT9 7AB, UK., Hurwitz J; Belfast Health and Social Care Trust, Belfast City Hospital, Lisburn Road, Belfast, BT9 7AB, UK., Kirk SJ; South Eastern Health and Social Care Trust, Ulster Hospital, Upper Newtownards Road, BT 16 1RH, Dundonald, UK., Xu J; Precision Medicine Centre, Patrick G Johnston Centre for Cancer Research, Queen's University Belfast, 97 Lisburn Road, Belfast, BT9 7AE, UK., Sidi FA; Precision Medicine Centre, Patrick G Johnston Centre for Cancer Research, Queen's University Belfast, 97 Lisburn Road, Belfast, BT9 7AE, UK., Humphries MP; Precision Medicine Centre, Patrick G Johnston Centre for Cancer Research, Queen's University Belfast, 97 Lisburn Road, Belfast, BT9 7AE, UK., Bingham V; Precision Medicine Centre, Patrick G Johnston Centre for Cancer Research, Queen's University Belfast, 97 Lisburn Road, Belfast, BT9 7AE, UK., James JA; Precision Medicine Centre, Patrick G Johnston Centre for Cancer Research, Queen's University Belfast, 97 Lisburn Road, Belfast, BT9 7AE, UK., James CR; Belfast Health and Social Care Trust, Belfast City Hospital, Lisburn Road, Belfast, BT9 7AB, UK., Paul Harkin D; Patrick G Johnston Centre for Cancer Research, Queen's University Belfast, 97 Lisburn Road, Belfast, BT9 7AE, UK.; Almac Diagnostic Services, Almac Group, 19 Seagoe Industrial Estate, Craigavon, BT63 5QD, UK., Kennedy RD; Patrick G Johnston Centre for Cancer Research, Queen's University Belfast, 97 Lisburn Road, Belfast, BT9 7AE, UK.; Almac Diagnostic Services, Almac Group, 19 Seagoe Industrial Estate, Craigavon, BT63 5QD, UK., McIntosh SA; Patrick G Johnston Centre for Cancer Research, Queen's University Belfast, 97 Lisburn Road, Belfast, BT9 7AE, UK. s.mcintosh@qub.ac.uk.; Belfast Health and Social Care Trust, Belfast City Hospital, Lisburn Road, Belfast, BT9 7AB, UK. s.mcintosh@qub.ac.uk.
Publikováno v:
British journal of cancer [Br J Cancer] 2022 Feb; Vol. 126 (2), pp. 247-258. Date of Electronic Publication: 2021 Nov 02.
Autor:
Turkington RC; Centre for Cancer Research and Cell Biology, Queen's University Belfast, Belfast, UK., Knight LA; Almac Diagnostics Ltd, Craigavon, UK., Blayney JK; Centre for Cancer Research and Cell Biology, Queen's University Belfast, Belfast, UK., Secrier M; Genetics Institute, University College London, London, UK., Douglas R; Centre for Cancer Research and Cell Biology, Queen's University Belfast, Belfast, UK., Parkes EE; Centre for Cancer Research and Cell Biology, Queen's University Belfast, Belfast, UK., Sutton EK; Centre for Cancer Research and Cell Biology, Queen's University Belfast, Belfast, UK., Stevenson L; Centre for Cancer Research and Cell Biology, Queen's University Belfast, Belfast, UK., McManus D; Department of Pathology, Belfast Health and Social Care Trust, Belfast, UK., Halliday S; Centre for Cancer Research and Cell Biology, Queen's University Belfast, Belfast, UK., McCavigan AM; Almac Diagnostics Ltd, Craigavon, UK., Logan GE; Almac Diagnostics Ltd, Craigavon, UK., Walker SM; Almac Diagnostics Ltd, Craigavon, UK., Steele CJ; Almac Diagnostics Ltd, Craigavon, UK., Perner J; Cancer Research UK Cambridge Institute, University of Cambridge, Cambridge, UK., Bornschein J; Translational Gastroenterology Unit, John Radcliffe Hospital Oxford University Hospitals NHS Trust, Oxford, UK., MacRae S; Hutchison/MRC Research Centre, Cambridge, UK., Miremadi A; Department of Histopathology, Addenbrookes Hospital, Cambridge, UK., McCarron E; Department of Pathology, Belfast Health and Social Care Trust, Belfast, UK., McQuaid S; Northern Ireland Molecular Pathology Laboratory, Queen's University Belfast, Belfast, UK., Arthur K; Northern Ireland Molecular Pathology Laboratory, Queen's University Belfast, Belfast, UK., James JA; Northern Ireland Molecular Pathology Laboratory, Queen's University Belfast, Belfast, UK., Eatock MM; Centre for Cancer Research and Cell Biology, Queen's University Belfast, Belfast, UK.; Department of Medical Oncology, Belfast Health and Social Care Trust, Belfast, UK., O'Neill R; Edinburgh Cancer Research Centre, University of Edinburgh, Edinburgh, UK., Noble F; Department of Surgery, University Hospital Southampton NHS Foundation Trust, Southampton, UK., Underwood TJ; Cancer Sciences Division, University of Southampton, Southampton, UK., Harkin DP; Almac Diagnostics Ltd, Craigavon, UK., Salto-Tellez M; Centre for Cancer Research and Cell Biology, Queen's University Belfast, Belfast, UK., Fitzgerald RC; Hutchison/MRC Research Centre, Cambridge, UK., Kennedy RD; Centre for Cancer Research and Cell Biology, Queen's University Belfast, Belfast, UK.; Almac Diagnostics Ltd, Craigavon, UK.
Publikováno v:
Gut [Gut] 2019 Nov; Vol. 68 (11), pp. 1918-1927. Date of Electronic Publication: 2019 Mar 09.
Autor:
Parkes EE; Affiliations of authors: Centre for Cancer Research and Cell Biology (EEP, SMW, LET, NM, RW, KDM, NEB, KIS, MST, SM, MTH, PBM, DPH, RDK) and Northern Ireland Molecular Pathology Laboratory (MST, SM), Queens University Belfast, Northern Ireland; Almac Diagnostics, Craigavon, Northern Ireland (SMW, LET, NM, LH, DPH, RDK)., Walker SM; Affiliations of authors: Centre for Cancer Research and Cell Biology (EEP, SMW, LET, NM, RW, KDM, NEB, KIS, MST, SM, MTH, PBM, DPH, RDK) and Northern Ireland Molecular Pathology Laboratory (MST, SM), Queens University Belfast, Northern Ireland; Almac Diagnostics, Craigavon, Northern Ireland (SMW, LET, NM, LH, DPH, RDK)., Taggart LE; Affiliations of authors: Centre for Cancer Research and Cell Biology (EEP, SMW, LET, NM, RW, KDM, NEB, KIS, MST, SM, MTH, PBM, DPH, RDK) and Northern Ireland Molecular Pathology Laboratory (MST, SM), Queens University Belfast, Northern Ireland; Almac Diagnostics, Craigavon, Northern Ireland (SMW, LET, NM, LH, DPH, RDK)., McCabe N; Affiliations of authors: Centre for Cancer Research and Cell Biology (EEP, SMW, LET, NM, RW, KDM, NEB, KIS, MST, SM, MTH, PBM, DPH, RDK) and Northern Ireland Molecular Pathology Laboratory (MST, SM), Queens University Belfast, Northern Ireland; Almac Diagnostics, Craigavon, Northern Ireland (SMW, LET, NM, LH, DPH, RDK)., Knight LA; Affiliations of authors: Centre for Cancer Research and Cell Biology (EEP, SMW, LET, NM, RW, KDM, NEB, KIS, MST, SM, MTH, PBM, DPH, RDK) and Northern Ireland Molecular Pathology Laboratory (MST, SM), Queens University Belfast, Northern Ireland; Almac Diagnostics, Craigavon, Northern Ireland (SMW, LET, NM, LH, DPH, RDK)., Wilkinson R; Affiliations of authors: Centre for Cancer Research and Cell Biology (EEP, SMW, LET, NM, RW, KDM, NEB, KIS, MST, SM, MTH, PBM, DPH, RDK) and Northern Ireland Molecular Pathology Laboratory (MST, SM), Queens University Belfast, Northern Ireland; Almac Diagnostics, Craigavon, Northern Ireland (SMW, LET, NM, LH, DPH, RDK)., McCloskey KD; Affiliations of authors: Centre for Cancer Research and Cell Biology (EEP, SMW, LET, NM, RW, KDM, NEB, KIS, MST, SM, MTH, PBM, DPH, RDK) and Northern Ireland Molecular Pathology Laboratory (MST, SM), Queens University Belfast, Northern Ireland; Almac Diagnostics, Craigavon, Northern Ireland (SMW, LET, NM, LH, DPH, RDK)., Buckley NE; Affiliations of authors: Centre for Cancer Research and Cell Biology (EEP, SMW, LET, NM, RW, KDM, NEB, KIS, MST, SM, MTH, PBM, DPH, RDK) and Northern Ireland Molecular Pathology Laboratory (MST, SM), Queens University Belfast, Northern Ireland; Almac Diagnostics, Craigavon, Northern Ireland (SMW, LET, NM, LH, DPH, RDK)., Savage KI; Affiliations of authors: Centre for Cancer Research and Cell Biology (EEP, SMW, LET, NM, RW, KDM, NEB, KIS, MST, SM, MTH, PBM, DPH, RDK) and Northern Ireland Molecular Pathology Laboratory (MST, SM), Queens University Belfast, Northern Ireland; Almac Diagnostics, Craigavon, Northern Ireland (SMW, LET, NM, LH, DPH, RDK)., Salto-Tellez M; Affiliations of authors: Centre for Cancer Research and Cell Biology (EEP, SMW, LET, NM, RW, KDM, NEB, KIS, MST, SM, MTH, PBM, DPH, RDK) and Northern Ireland Molecular Pathology Laboratory (MST, SM), Queens University Belfast, Northern Ireland; Almac Diagnostics, Craigavon, Northern Ireland (SMW, LET, NM, LH, DPH, RDK)., McQuaid S; Affiliations of authors: Centre for Cancer Research and Cell Biology (EEP, SMW, LET, NM, RW, KDM, NEB, KIS, MST, SM, MTH, PBM, DPH, RDK) and Northern Ireland Molecular Pathology Laboratory (MST, SM), Queens University Belfast, Northern Ireland; Almac Diagnostics, Craigavon, Northern Ireland (SMW, LET, NM, LH, DPH, RDK)., Harte MT; Affiliations of authors: Centre for Cancer Research and Cell Biology (EEP, SMW, LET, NM, RW, KDM, NEB, KIS, MST, SM, MTH, PBM, DPH, RDK) and Northern Ireland Molecular Pathology Laboratory (MST, SM), Queens University Belfast, Northern Ireland; Almac Diagnostics, Craigavon, Northern Ireland (SMW, LET, NM, LH, DPH, RDK)., Mullan PB; Affiliations of authors: Centre for Cancer Research and Cell Biology (EEP, SMW, LET, NM, RW, KDM, NEB, KIS, MST, SM, MTH, PBM, DPH, RDK) and Northern Ireland Molecular Pathology Laboratory (MST, SM), Queens University Belfast, Northern Ireland; Almac Diagnostics, Craigavon, Northern Ireland (SMW, LET, NM, LH, DPH, RDK)., Harkin DP; Affiliations of authors: Centre for Cancer Research and Cell Biology (EEP, SMW, LET, NM, RW, KDM, NEB, KIS, MST, SM, MTH, PBM, DPH, RDK) and Northern Ireland Molecular Pathology Laboratory (MST, SM), Queens University Belfast, Northern Ireland; Almac Diagnostics, Craigavon, Northern Ireland (SMW, LET, NM, LH, DPH, RDK)., Kennedy RD; Affiliations of authors: Centre for Cancer Research and Cell Biology (EEP, SMW, LET, NM, RW, KDM, NEB, KIS, MST, SM, MTH, PBM, DPH, RDK) and Northern Ireland Molecular Pathology Laboratory (MST, SM), Queens University Belfast, Northern Ireland; Almac Diagnostics, Craigavon, Northern Ireland (SMW, LET, NM, LH, DPH, RDK).
Publikováno v:
Journal of the National Cancer Institute [J Natl Cancer Inst] 2016 Oct 05; Vol. 109 (1). Date of Electronic Publication: 2016 Oct 05 (Print Publication: 2017).
Autor:
Parkes, Eileen E., Savage, Kienan I., Lioe, Tong, Boyd, Clinton, Halliday, Sophia, Walker, Steven M., Lowry, Keith, Knight, Laura, Buckley, Niamh E., Grogan, Andrena, Logan, Gemma E., Clayton, Alison, Hurwitz, Jane, Kirk, Stephen J., Xu, Jiamei, Sidi, Fatima Abdullahi, Humphries, Matthew P., Bingham, Victoria, Ang, Melvyn, Askin, Conal, Bamford, Louise, Boyd, Ruth, Buckley, Miriam, Clarke, Jacqueline, Darragh, Lynn, Davis, Elaine, Foreman, Jennifer, Gallagher, Rebecca, Gill, Janine, Hanna, Michael, Hill, Naomi, Irwin, Gareth, Mallon, Peter, McAleer, Seamus, McAllister, Joanne, Morris, Melanie, Pierce, Nicole, Refsum, Sigi, Sloan, Samantha, Treanor, Sinead, James, Jacqueline, James, Colin R., Paul Harkin, D., Kennedy, Richard D., McIntosh, Stuart A.
Publikováno v:
Parkes, E E, Savage, K I, Lioe, T, Boyd, C, Halliday, S, Walker, S M, Lowry, K, Knight, L, Buckley, N E, Grogan, A, Logan, G E, Clayton, A, Hurwitz, J, Kirk, S J, Xu, J, Sidi, F A, Humphries, M P, Bingham, V, Ang, M, Askin, C, Bamford, L, Boyd, R, Buckley, M, Clarke, J, Darragh, L, Davis, E, Foreman, J, Gallagher, R, Gill, J, Hanna, M, Hill, N, Irwin, G, Mallon, P, McAleer, S, McAllister, J, Morris, M, Pierce, N, Refsum, S, Sloan, S, Treanor, S, James, J, James, C R, Paul Harkin, D, Kennedy, R D & McIntosh, S A 2022, ' Activation of a cGAS-STING-mediated immune response predicts response to neoadjuvant chemotherapy in early breast cancer ', British Journal of Cancer, vol. 126, no. 2, pp. 247-258 . https://doi.org/10.1038/s41416-021-01599-0
British Journal of Cancer
British Journal of Cancer
Background The DNA-damage immune-response (DDIR) signature is an immune-driven gene expression signature retrospectively validated as predicting response to anthracycline-based therapy. This feasibility study prospectively evaluates the use of this a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::89093693d780af5cb3b489f2e8467878
https://pure.qub.ac.uk/en/publications/ddcf60ae-b538-40b3-8534-1226cc8804ab
https://pure.qub.ac.uk/en/publications/ddcf60ae-b538-40b3-8534-1226cc8804ab
Autor:
Parkes, Eileen E., Walker, Steven M., Taggart, Laura E., McCabe, Nuala, Knight, Laura A., Wilkinson, Richard, McCloskey, Karen D., Buckley, Niamh E., Savage, Kienan I., Salto-Tellez, Manuel, McQuaid, Stephen, Harte, Mary T., Mullan, Paul B., Harkin, D. Paul, Kennedy, Richard D.
Publikováno v:
JNCI: Journal of the National Cancer Institute; 1/13/2017, Vol. 109 Issue 1, p1-10, 10p, 2 Charts, 4 Graphs
Autor:
Turkington, Richard C, Knight, Laura A, Blayney, Jaine K, Secrier, Maria, Douglas, Rosalie, Parkes, Eileen E, Sutton, Eilis K, Stevenson, Leanne, McManus, Damian, Halliday, Sophia, McCavigan, Andrena M, Logan, Gemma E, Walker, Steven M, Steele, Christopher J, Perner, Juliane, Bornschein, Jan, MacRae, Shona, Miremadi, Ahmad, McCarron, Eamon, McQuaid, Stephen, Arthur, Kenneth, James, Jacqueline A, Eatock, Martin M, O'Neill, Robert, Noble, Fergus, Underwood, Timothy J, Harkin, D Paul, Salto-Tellez, Manuel, Fitzgerald, Rebecca C, Kennedy, Richard D, Oesophageal Cancer Clinical And Molecular Stratification (OCCAMS) Study Group
OBJECTIVE: Current strategies to guide selection of neoadjuvant therapy in oesophageal adenocarcinoma (OAC) are inadequate. We assessed the ability of a DNA damage immune response (DDIR) assay to predict response following neoadjuvant chemotherapy in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e6eaf5d6bf3145806002b547acc8e107