Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Tomi P. Mäkelä"'
Autor:
Olli-Pekka Kallioniemi, Mervi Heiskanen, Kari Alitalo, Leena Peltonen, Aarno Palotie, Tomi P. Mäkelä, Elina Hellsten
Publikováno v:
Genomics. 30:31-36
FISH techniques have opened new possibilities for high-resolution genome mapping. Effective utilization of these techniques for the rapid orientation and ordering of adjacent and overlapping probes as well as for the characterization of long-range ge
Publikováno v:
Nature. 377:557-560
AN array of tandem heptapeptide repeats at the carboxv -terminal domain (CTD) of the largest subunit of RNA polymerase II constitute a highly conserved structure essential for viability1a¤-3. Studies have established that the CTD is phosphorylated a
Autor:
Tomi P. Mäkelä, Irma Järvelä, Kari Alitalo, Leena Peltonen, J. Vesa, Marcy C. Speer, Elina Hellsten, Jurg Ott
Publikováno v:
Genomics. 16:720-725
Infantile neuronal ceroid lipofuscinosis, INCL, CLN1, is an autosomally inherited progressive neurogenerative disorder. The disease results in the massive death of cortical neurons, suggesting an essential role for the CLN1 gene product in the normal
Publikováno v:
Science. 256:373-377
Max is a basic-helix-loop-helix-leucine zipper protein capable of forming sequence-specific DNA binding complexes with Myc proteins. An alternatively spliced messenger RNA has been identified that encodes a form of Max truncated at the COOH-terminus.
Autor:
Juha Partanen, Kari Alitalo, Elina Eerola, Lena Claesson-Welsh, Jaana Korhonen, H. Hirvonen, Tomi P. Mäkelä
Publikováno v:
The EMBO Journal. 10:1347-1354
We have previously identified two novel members of the fibroblast growth factor receptor (FGFR) gene family expressed in K562 erythroleukemia cells. Here we report cDNA cloning and analysis of one of these genes, named FGFR-4. The deduced amino acid
Publikováno v:
Proceedings of the National Academy of Sciences. 87:8913-8917
Tyrosine phosphorylation is important in the transmission of growth and differentiation signals; known tyrosine kinases include several oncoproteins and growth factor receptors. Interestingly, some differentiated cell types, such as erythrocytes and
Autor:
Robert A. Weinberg, Graham J. Hughes, Tomi P. Mäkelä, Erich A. Nigg, Jean-Pierre Tassan, Séverine Frutiger
Publikováno v:
Nature. 371(6494)
The eukaryotic cell cycle is regulated by the sequential activation of cyclin-dependent kinases (CDKs). CDK activation is dependent on cyclin binding and phosphorylation of a conserved threonine (T161 in Cdc2) mediated by the CDK-activating kinase CA
Publikováno v:
Clinica chimica acta; international journal of clinical chemistry. 217(1)
The myc oncogenes have been implicated in the control of cell proliferation in both normal and neoplastic cells. There is increasing evidence that Myc proteins function as transcriptional regulators of other genes apparently involved in the control o
Publikováno v:
Human molecular genetics. 1(3)
Autor:
Aarno Palotie, Mervi Heiskanen, Elina Hellsten, Tomi P. Mäkelä, Kari Alitalo, Olli-Pekka Kallioniemi
Publikováno v:
Cancer Genetics and Cytogenetics. 84:133