Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Takehiko Yasuji"'
Autor:
Takehiko Yasuji, Keiichi Yoshihara, Kazuhiro Sako, Yuuki Kasashima, Noriyuki Namiki, Shinya Uchida
Publikováno v:
CHEMICAL & PHARMACEUTICAL BULLETIN. 64:1304-1309
The objective of this study was to establish the key factor of the lauryl sulfate (LS) salt/complex for sustained release of a hydrophilic drug at various physiological pH levels. Mirabegron is a hydrophilic drug that exhibits pH-dependent solubility
Autor:
Yuuki Kasashima, Takehiko Yasuji, Shinya Uchida, Kazuhiro Sako, Keiichi Yoshihara, Noriyuki Namiki
Publikováno v:
International journal of pharmaceutics. 515(1-2)
The objective of this study was to evaluate the feasibility of lauryl sulfate (LS) salt/complex as a novel carrier in oral sustained-release suspensions. Mirabegron, which has a pH-dependent solubility, was selected as the model drug. Sodium lauryl s
Publikováno v:
Advanced drug delivery reviews. 60(3)
In order to improve the dissolution properties of poorly water-soluble drugs, some drugs were subjected to micronization or prepared as composite particles using supercritical fluid (SCF) technology with carbon dioxide (CO(2)). Solubility in CO(2) is