Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Takashi Sono"'
Autor:
Mark T. Waddingham, Hirotsugu Tsuchimochi, Takashi Sonobe, Vasco Sequeira, Md Junayed Nayeem, Mikiyasu Shirai, James T. Pearson, Takeshi Ogo
Publikováno v:
Journal of Molecular and Cellular Cardiology Plus, Vol 8, Iss , Pp 100072- (2024)
Background: Pulmonary hypertension (PH) often leads to right ventricle (RV) failure, a significant cause of morbidity and mortality. Despite advancements in PH management, progression to RV maladaptation and subsequent failure remain a clinical chall
Externí odkaz:
https://doaj.org/article/c799fd064dab4b7da859a49b8d77c099
Autor:
Takashi Sonobe, Yoshihiko Kakinuma
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 11 (2024)
Vascular endothelial cells play an important role in regulating peripheral circulation by modulating arterial tone in the microvasculature. Elevated intracellular Ca2+ levels are required in endothelial cells to induce smooth muscle relaxation via en
Externí odkaz:
https://doaj.org/article/66afcf96db9b4b8380be38741f9d6e5c
Autor:
Vijayakumar Sukumaran, Hirotsugu Tsuchimochi, Takashi Sonobe, Mark T. Waddingham, Mikiyasu Shirai, James T. Pearson
Publikováno v:
Cardiovascular Diabetology, Vol 19, Iss 1, Pp 1-16 (2020)
Abstract Background Obesity, hypertension and prediabetes contribute greatly to coronary artery disease, heart failure and vascular events, and are the leading cause of mortality and morbidity in developed societies. Salt sensitivity exacerbates endo
Externí odkaz:
https://doaj.org/article/9ba970a0e7c64c4fbc20a76b36f501d3
Autor:
James T Pearson, Mikiyasu Shirai, Vijayakumar Sukumaran, Cheng-Kun Du, Hirotsugu Tsuchimochi, Takashi Sonobe, Mark T Waddingham, Rajesh Katare, Daryl O Schwenke
Publikováno v:
Vascular Biology, Vol 1, Iss 1, Pp H97-H102 (2019)
Ghrelin is a small peptide with important roles in the regulation of appetite, gut motility, glucose homeostasis as well as cardiovascular protection. This review highlights the role that acyl ghrelin plays in maintaining normal endothelial function
Externí odkaz:
https://doaj.org/article/5a0dbb4f12df4203bf8e2a9d84c7af1a