Zobrazeno 11 - 20
of 252
pro vyhledávání: '"Preclinical research"'
Autor:
Hartung T; Johns Hopkins University, Bloomberg School of Public Health, Center for Alternatives to Animal Testing (CAAT), Baltimore, MD, USA.; University of Konstanz, CAAT-Europe, Konstanz, Germany.
Publikováno v:
ALTEX [ALTEX] 2017; Vol. 34 (2), pp. 193-200.
Autor:
Tadeo Bermudez, Saad Sammani, Jin H. Song, Vivian Reyes Hernon, Carrie L. Kempf, Alexander N. Garcia, Jessica Burt, Matthew Hufford, Sara M. Camp, Anne E. Cress, Ankit A. Desai, Viswanathan Natarajan, Jeffrey R. Jacobson, Steven M. Dudek, Leopoldo C. Cancio, Julie Alvarez, Ruslan Rafikov, Yansong Li, Donna D. Zhang, Nancy G. Casanova, Christian Bime, Joe G. N. Garcia
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-12 (2022)
Scientific Reports
Scientific Reports
Despite encouraging preclinical data, therapies to reduce ARDS mortality remains a globally unmet need, including during the COVID-19 pandemic. We previously identified extracellular nicotinamide phosphoribosyltransferase (eNAMPT) as a novel damage-a
Autor:
Schubert R; George-Huntington-Institute, Technology Park, Johann-Krane-Weg 27, 48149 Muenster, Germany., Frank F; George-Huntington-Institute, Technology Park, Johann-Krane-Weg 27, 48149 Muenster, Germany; Dept of Radiology, University of Muenster, Albert-Schweitzer Campus 1, 48149 Muenster, Germany., Nagelmann N; Dept of Radiology, University of Muenster, Albert-Schweitzer Campus 1, 48149 Muenster, Germany., Liebsch L; Dept of Radiology, University of Muenster, Albert-Schweitzer Campus 1, 48149 Muenster, Germany., Schuldenzucker V; George-Huntington-Institute, Technology Park, Johann-Krane-Weg 27, 48149 Muenster, Germany., Schramke S; George-Huntington-Institute, Technology Park, Johann-Krane-Weg 27, 48149 Muenster, Germany; Institute for Animal Hygiene, Animal Welfare and Farm Animal Behaviour, University of Veterinary Medicine Hannover, Bischofsholer Damm 15, 30173 Hannover, Germany., Wirsig M; George-Huntington-Institute, Technology Park, Johann-Krane-Weg 27, 48149 Muenster, Germany., Johnson H; Dept of Psychiatry, University of Iowa, IowaCity, IA, USA; Electrical and Computer Engineering, University of Iowa, IowaCity, IA, USA., Kim EY; Dept of Psychiatry, University of Iowa, IowaCity, IA, USA., Ott S; George-Huntington-Institute, Technology Park, Johann-Krane-Weg 27, 48149 Muenster, Germany., Hölzner E; George-Huntington-Institute, Technology Park, Johann-Krane-Weg 27, 48149 Muenster, Germany., Demokritov SO; Department of Physics and Center for Nonlinear Science, University of Muenster, Germany., Motlik J; Laboratory of Cell Regeneration and Plasticity, Institute of Animal Physiology and Genetics, v.v.i., AS CR, Libechov, Czech Republic., Faber C; Dept of Radiology, University of Muenster, Albert-Schweitzer Campus 1, 48149 Muenster, Germany., Reilmann R; George-Huntington-Institute, Technology Park, Johann-Krane-Weg 27, 48149 Muenster, Germany; Dept of Radiology, University of Muenster, Albert-Schweitzer Campus 1, 48149 Muenster, Germany; Department of Neurology, University of Munster, Germany; Department of Neurodegenerative Diseases and Hertie-Institute for Clinical Brain Research, University of Tuebingen, Hoppe-Seyler Str. 3, 72076 Tuebingen, Germany. Electronic address: ralf.reilmann@ghi-muenster.de.
Publikováno v:
Journal of neuroscience methods [J Neurosci Methods] 2016 May 30; Vol. 265, pp. 46-55. Date of Electronic Publication: 2015 Dec 01.
Autor:
Schramke S; George-Huntington-Institute, Technology Park Muenster, Johann-Krane Weg 27 48149, Muenster, Germany; Institute for Animal Hygiene, Animal Welfare and Farm Animal Behaviour, University of Veterinary Medicine Hannover, Bischofsholer Damm 15 30173, Hannover, Germany., Schuldenzucker V; George-Huntington-Institute, Technology Park Muenster, Johann-Krane Weg 27 48149, Muenster, Germany., Schubert R; George-Huntington-Institute, Technology Park Muenster, Johann-Krane Weg 27 48149, Muenster, Germany., Frank F; George-Huntington-Institute, Technology Park Muenster, Johann-Krane Weg 27 48149, Muenster, Germany; Laboratory of Cell Regeneration and Plasticity, Institute of Animal Physiology and Genetics, v.v.i., AS CR, Libechov, Czech Republic., Wirsig M; George-Huntington-Institute, Technology Park Muenster, Johann-Krane Weg 27 48149, Muenster, Germany., Ott S; George-Huntington-Institute, Technology Park Muenster, Johann-Krane Weg 27 48149, Muenster, Germany., Motlik J; Laboratory of Cell Regeneration and Plasticity, Institute of Animal Physiology and Genetics, v.v.i., AS CR, Libechov, Czech Republic., Fels M; Institute for Animal Hygiene, Animal Welfare and Farm Animal Behaviour, University of Veterinary Medicine Hannover, Bischofsholer Damm 15 30173, Hannover, Germany., Kemper N; Institute for Animal Hygiene, Animal Welfare and Farm Animal Behaviour, University of Veterinary Medicine Hannover, Bischofsholer Damm 15 30173, Hannover, Germany., Hölzner E; George-Huntington-Institute, Technology Park Muenster, Johann-Krane Weg 27 48149, Muenster, Germany., Reilmann R; George-Huntington-Institute, Technology Park Muenster, Johann-Krane Weg 27 48149, Muenster, Germany; Department of Radiology, Universitaetsklinikum Muenster, Albert-Schweitzer Campus 1 48149, Muenster, Germany; Dept of Neurology Muenster, Germany; Department of Neurodegenerative Diseases and Hertie-Institute for Clinical Brain Research, University of Tuebingen, Hoppe-Seyler Str. 3 72076 Tuebingen, Germany. Electronic address: ralf.reilmann@ghi-muenster.de.
Publikováno v:
Journal of neuroscience methods [J Neurosci Methods] 2016 May 30; Vol. 265, pp. 34-45. Date of Electronic Publication: 2015 Dec 11.
Autor:
Skrypnyk NI; Division of Nephology and Hypertension, Vanderbilt University Medical Center, Nashville, Tennessee;, Siskind LJ; Department of Pharmacology and Toxicology, James Graham Brown Cancer Center, University of Louisville, Louisville, Kentucky; and., Faubel S; Renal Division, University of Colorado Denver and Denver Veterans Affairs Medical Center, Aurora, Colorado., de Caestecker MP; Division of Nephology and Hypertension, Vanderbilt University Medical Center, Nashville, Tennessee; mark.de.caestecker@vanderbilt.edu.
Publikováno v:
American journal of physiology. Renal physiology [Am J Physiol Renal Physiol] 2016 May 15; Vol. 310 (10), pp. F972-84. Date of Electronic Publication: 2016 Mar 09.
Autor:
Langston RG; Cell Biology and Gene Expression Section, Laboratory of Neurogenetics, NIA, NIH, Bethesda, MD 20892, U.S.A., Rudenko IN; Cell Biology and Gene Expression Section, Laboratory of Neurogenetics, NIA, NIH, Bethesda, MD 20892, U.S.A., Cookson MR; Cell Biology and Gene Expression Section, Laboratory of Neurogenetics, NIA, NIH, Bethesda, MD 20892, U.S.A. cookson@mail.nih.gov.
Publikováno v:
The Biochemical journal [Biochem J] 2016 Feb 01; Vol. 473 (3), pp. 221-32.
Autor:
M. Pilar Vinardell
Publikováno v:
Dipòsit Digital de la UB
Universidad de Barcelona
Universidad de Barcelona
Psoriasis is a chronic inflammatory skin disease affecting about 2-3% of the worldwide population. More of the knowledge of psoriasis is due to the in vitro and in vivo models tried to reproduce the disease and to know the mechanisms of pathogenesis,
Autor:
Morikazu Miyamoto, Manabu Kinoshita, Hiroki Ishibashi, Kohsuke Hagisawa, Tomoko Kure, Yukako Yuki, Hiromi Sakai, Masashi Takano, Katsuo Terui, Daizoh Saitoh
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-12 (2021)
Scientific Reports
Scientific Reports
We aimed to investigate the resuscitative efficacy of hemoglobin vesicles (HbVs) as a red blood cell (RBC) substitute for the initial treatment of severe postpartum hemorrhage (PPH). Twenty-five pregnant rabbits underwent cesarean section; uncontroll
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-12 (2021)
Scientific Reports
Scientific Reports
Molecular imaging using singlechain variable fragments (scFv) of antibodies targeting cancer specific antigens have been considered a non-immunogenic approach for early diagnosis in the clinic. Usually, production of proteins is performed within Esch
Autor:
Dake Qi, Siqian Fu, Cui Li, Baiyang You, Suixin Liu, Fan Zheng, Wenliang Zhang, Jeffrey W. Ripley-Gonzalez, Ling Qiu, Yaoshan Dun
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-12 (2021)
Scientific Reports
Scientific Reports
Obesity induces skeletal muscle dysfunction. The pathogenesis of which appears to substantially involve mitochondrial dysfunction, arising from impaired quality control. Exercise is a major therapeutic strategy against muscle dysfunction. Trimetazidi