Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Leandro F. Vendruscolo"'
Autor:
Kenneth J. Sher, Andrea C. King, Lara A. Ray, Ashley Vena, John Kramer, Leandro F. Vendruscolo, Danielle M. Dick, Laura Acion
Publikováno v:
Alcohol Alcohol
Alcohol and alcoholism (Oxford, Oxfordshire), vol 55, iss 6
Alcohol and alcoholism (Oxford, Oxfordshire), vol 55, iss 6
Aim The purpose of this brief narrative review is to address the complexities and benefits of extending animal alcohol addiction research to the human domain, emphasizing Allostasis and Incentive Sensitization, two models that inform many pre-clinica
Autor:
Caroline Smith, Leandro F. Vendruscolo, Michael A. Arends, Sophie K. Elvig, M. Adrienne McGinn, George F. Koob
Publikováno v:
Pharmacol Biochem Behav
Alcohol tolerance refers to a lower effect of alcohol with repeated exposure. Although alcohol tolerance has been historically included in diagnostic manuals as one of the key criteria for a diagnosis of alcohol use disorder (AUD), understanding its
Autor:
Yuan Ru Yang, Leandro F. Vendruscolo, Brandon A. Blank, Pal Pacher, Ji Soo Lee, Eszter Trojnar, Nehal N. Mehta, George F. Koob, Csaba Mátyás, Alexander V. Sorokin, Janaina C. M. Vendruscolo, Partha Mukhopadhyay, Cody Savage, Falk W. Lohoff, János Pálóczi
Publikováno v:
Scientific Reports
Scientific Reports, Vol 9, Iss 1, Pp 1-16 (2019)
Scientific Reports, Vol 9, Iss 1, Pp 1-16 (2019)
Alcoholic liver disease (ALD) causes significant morbidity and mortality, and pharmacological treatment options are limited. In this study, we evaluated the PCSK9 inhibitor alirocumab, a monoclonal antibody that robustly reduces low-density lipoprote
Autor:
Candice Contet, Sucharita S. Somkuwar, Jasmin Guevara, Eric P. Zorrilla, McKenzie J. Fannon, Chitra D. Mandyam, Tran Bao Nguyen, Leandro F. Vendruscolo, Brooke E. Schmeichel, Harpreet Sidhu
Publikováno v:
Psychoneuroendocrinology. 84:17-31
Alcohol dependence is linked to dysregulation of the hypothalamic-pituitary-adrenal axis. Here, we investigated effects of repeated ethanol intoxication-withdrawal cycles (using chronic intermittent ethanol vapor inhalation; CIE) and abstinence from
Autor:
Olivier George, Giordano de Guglielmo, Leandro F. Vendruscolo, Elena Crawford, Molly Brennan, Maury Cole, Bruce T. Hope, George F. Koob, Sarah Kim
Publikováno v:
The Journal of neuroscience : the official journal of the Society for Neuroscience, vol 36, iss 36
Abstinence from alcohol is associated with the recruitment of neurons in the central nucleus of the amygdala (CeA) in nondependent rats that binge drink alcohol and in alcohol-dependent rats. However, whether the recruitment of this neuronal ensemble
Publikováno v:
Alcoholism, clinical and experimental researchReferences. 44(2)
Alcohol use disorder (AUD) and chronic pain are enduring and devastating conditions that share an intersecting epidemiology and neurobiology. Chronic alcohol use itself can produce a characteristic painful neuropathy, while the regular analgesic use
Autor:
Priscila Darakjian, Leandro F. Vendruscolo, Carolina L. Haass-Koffler, Lorenzo Leggio, Giovanni Addolorato, Markus Heilig, Anna Ferrulli, Estelle Barbier, Robert Hitzemann, Vanessa A. Jimenez, Elie Aoun, Kathleen A. Grant, N. A. R. Walter, George F. Koob, Mary R. Lee
Publikováno v:
Molecular psychiatry
Aldosterone regulates electrolyte and fluid homeostasis through binding to the mineralocorticoid receptors (MRs). Previous work provides evidence for a role of aldosterone in alcohol use disorders (AUDs). We tested the hypothesis that high functional
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::103f12f87d293d6957366b59b65b4ca6
http://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-149720
http://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-149720
Publikováno v:
Current Drug Abuse Reviewse. 2:177-183
The co-occurrence of drug addiction in adults with attention deficit hyperactivity disorder (ADHD) is very common, but its etiology remains largely unknown. Therefore, animal models to study this kind of psychiatric comorbidity are needed. The Sponta
Autor:
Abbey Borich, Caleb Pitcairn, Hui Sun, Markus Heilig, Jesse R. Schank, Zhifeng Zhou, Kornel E. Schuebel, Leandro F. Vendruscolo, Estelle Barbier, Jenica D. Tapocik, Qiaoping Yuan, David Goldman, Nathan Juergens
Recent studies have suggested an association between alcoholism and DNA methylation, a mechanism that can mediate long-lasting changes in gene transcription. Here, we examined the contribution of DNA methylation to the long-term behavioral and molecu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8c3a959a2a0fa852aa6ff6d626bd368b
http://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-118052
http://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-118052
Autor:
Elena Terenina-Rigaldie, Frantz Raba, Reinaldo N. Takahashi, Pierre Mormède, André Ramos, Leandro F. Vendruscolo
Publikováno v:
Genes, Brain and Behavior
Genes, Brain and Behavior, Wiley, 2006, 5 (6), pp.441-450. ⟨10.1111/j.1601-183X.2005.00177.x⟩
Genes, Brain and Behavior, Wiley, 2006, 5 (6), pp.441-450. ⟨10.1111/j.1601-183X.2005.00177.x⟩
Previous studies using the inbred rat strains Lewis (LEW) and spontaneously hypertensive rats (SHR) led to the mapping of two quantitative trait loci, named Ofil1 (on chromosome 4 of the rat) and Ofil2 (on chromosome 7), for open-field inner locomoti