Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Katsinelos, Taxiarchis"'
Autor:
Mukadam, Aamir S, Miller, Lauren VC, Smith, Annabel E, Vaysburd, Marina, Sakya, Siri A, Sanford, Sophie, Keeling, Sophie, Tuck, Benjamin J, Katsinelos, Taxiarchis, Green, Chris, Skov, Lise, Kaalund, Sanne S, Foss, Stian, Mayes, Keith, O'Connell, Kevin, Wing, Mark, Knox, Claire, Banbury, Jessica, Avezov, Edward, Rowe, James B, Goedert, Michel, Andersen, Jan Terje, James, Leo C, McEwan, William A
Publikováno v:
Science. 379:1336-1341
Aggregates of the protein tau are proposed to drive pathogenesis in neurodegenerative diseases. Tau can be targeted by using passively transferred antibodies (Abs), but the mechanisms of Ab protection are incompletely understood. In this work, we use
Autor:
Miller, Lauren VC, Mukadam, Aamir S, Durrant, Claire S, Vaysburd, Marina J, Katsinelos, Taxiarchis, Tuck, Benjamin J, Sanford, Sophie, Sheppard, Olivia, Knox, Claire, Cheng, Shi, James, Leo C, Coleman, Michael P, McEwan, William A
A fundamental property of infectious agents is their particulate nature: infectivity arises from independently-acting particles rather than as a result of collective action. Assemblies of the protein tau can exhibit seeding behaviour, potentially und
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1c208b90438b9d7750816a96a1698667
Ordered assemblies of proteins are found in the postmortem brains of sufferers of several neurodegenerative diseases. The cytoplasmic microtubule associated protein tau and alpha-synuclein (αS) are found in an assembled state in Alzheimer's disease
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3de8ead5b781d3100aabd3cdb2506402
Publikováno v:
Frontiers in Immunology, Vol 10 (2019)
Frontiers in Immunology
Frontiers in Immunology
Ordered assemblies of proteins are found in the postmortem brains of sufferers of several neurodegenerative diseases. The cytoplasmic microtubule associated protein tau and alpha-synuclein (αS) are found in an assembled state in Alzheimer's disease