Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Pablo Muriel"'
Autor:
Sael Casas-Grajales, Carlos M. Cerda-García-Rojas, M. Raj Lakshman, Karina Reyes-Gordillo, Pablo Muriel, Víctor Tsutsumi
Publikováno v:
Journal of applied toxicology : JAT. 39(8)
Rebaudioside A (Reb A) is a diterpenoid isolated from the leaves of Stevia rebaudiana (Bertoni) that has been shown to possess pharmacological activity, including anti-inflammatory and antioxidant properties. However, the ability of Reb A to prevent
Autor:
Javier Camacho, Erika Ramos-Tovar, Sael Casas-Grajales, Erika Hernández-Aquino, Rosa E. Flores-Beltrán, Mineko Shibayama, Luis Vázquez-Flores, Pablo Muriel, Víctor Tsutsumi, Carlos M. Cerda-García-Rojas
Publikováno v:
Fundamental & Clinical Pharmacology.
The ability of quercetin to reverse an established cirrhosis has not yet been investigated. Therefore, the aim of this study was to examine the efficacy of this flavonoid in reversing experimental cirrhosis. Cirrhosis was induced by intraperitoneal a
Autor:
Liliana Favari, José Segovia, Pablo Muriel, Erika Hernández-Aquino, Natanael Zarco, Marina Galicia-Moreno, Jonathan Arauz
Publikováno v:
Nutrition research (New York, N.Y.). 40
Investigations demonstrated that oxidative stress plays an important role in injury promotion in cholestatic liver disease. We hypothesized that coffee attenuates cholestasis-induced hepatic necrosis and fibrosis via its antioxidant, anti-inflammator
Publikováno v:
European Journal of Gastroenterology & Hepatology. 24:179-185
Objectives Several studies have suggested that oxidative stress may play an important role in the pathogenesis of hepatic injury during cholestasis in rats and humans. The aim of this study was to evaluate the ability of N-acetylcysteine (NAC) to pre
Autor:
Pablo Muriel, Mineko Shibayama, Martha S. Morales-Ríos, Horacio Rivera, Víctor Pérez-Álvarez, Víctor Tsutsumi, Wendy Bautista
Publikováno v:
Canadian Journal of Physiology and Pharmacology. 89:759-766
There has been a recently increase in the development of novel stilbene-based compounds with in vitro anti-inflamatory properties. For this study, we synthesized and evaluated the anti-inflammatory properties of 2 fluorinated stilbenes on carbon tetr
Autor:
Pablo Muriel, Mineko Shibayama, Víctor Pérez-Álvarez, Víctor Tsutsumi, Eduardo Fernández-Martínez
Publikováno v:
Experimental and Toxicologic Pathology. 58:49-58
Chronic bile duct ligation (BDL) is a useful model of cirrhosis. However, its parallel plasma and liver changes in levels of cytokines and nitric oxide (NO), involved in liver damage, remain unknown. The aims of this work were to quantify both the pl
Autor:
J Eliuth, Pérez-Vargas, Natanael, Zarco, Mineko, Shibayama, José, Segovia, Víctor, Tsutsumi, Pablo, Muriel
Publikováno v:
Pharmacology. 94(1-2)
To evaluate the antioxidant, immunomodulatory, antinecrotic and antifibrotic effects of hesperidin on CCl4-induced cirrhosis.Liver damage was produced by giving CCl4 injections (0.4 g/kg, i.p., 3 times per week for 8 weeks) to rats. Hesperidin (200 m
Autor:
Pablo Muriel, Liseth R. Aldaba-Muruato, Mario G. Moreno, Elisa Hernández-Mercado, Mineko Shibayama
Publikováno v:
Canadian journal of physiology and pharmacology. 90(11)
Allopurinol is an inhibitor of xanthine oxidase (XO), and XO is an enzyme that generates great amounts of reactive oxygen species. The aim of this work was to evaluate the efficacy of allopurinol to prevent experimental cirrhosis. Fibrosis and cirrho
Autor:
Jonathan, Arauz, Marina Galicia-, Moreno, Pedro, Cortés-Reynosa, Eduardo Pérez, Salazar, Pablo, Muriel
Publikováno v:
Journal of applied toxicology : JAT. 33(9)
This study was performed to evaluate the antifibrotic properties of coffee in a model of liver damage induced by repeated administration of thioacetamide (TAA) in male Wistar rats. In this study, cirrhosis was induced by chronic TAA administration an
Autor:
Enrique, Chávez, José, Segovia, Mineko, Shibayama, Victor, Tsutsumi, Paula, Vergara, Luis, Castro-Sánchez, Eduardo Pérez, Salazar, Mario G, Moreno, Pablo, Muriel
Publikováno v:
Liver international : official journal of the International Association for the Study of the Liver. 30(7)
Transforming growth factor-beta (TGF-beta) plays a pivotal role in liver fibrosis, because it activates hepatic stellate cells, stimulating extracellular matrix deposition. Cyclooxygenase-2 (COX-2) has been associated with TGF-beta because its inhibi