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Autor:
Thoralf Opitz, Heinz Beck, Leonie Pothmann, Sarah Schmidt, Daniel Müller-Komorowska, Patrício Soares da Silva
Publikováno v:
Epilepsia. 62:542-556
Objective Many antiseizure drugs (ASDs) act on voltage-dependent sodium channels, and the molecular basis of these effects is well established. In contrast, how ASDs act on the level of neuronal networks is much less understood. Methods In the presen
Autor:
Maurizio Popoli, Lucia Carboni, Laura Caberlotto, Aleksander A. Mathé, Luca Marchetti, Laura Musazzi, Mario Lauria, Enrico Domenici
Publikováno v:
European Neuropsychopharmacology. 31:69-85
Neurobiological underpinnings of treatment-resistant depression, a debilitating condition associated with significant functional impairment, have not been elucidated. Consequently, the aim of this study was to use animal models of response and resist
Publikováno v:
The journal of pain, vol 22, iss 10
J Pain
J Pain
High molecular weight hyaluronan (HMWH), a prominent component of the extracellular matrix binds to and signals via multiple receptors, including cluster of differentiation 44 (CD44) and toll-like receptor 4 (TLR4). We tested the hypothesis that, in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5db008a5df89afa6bd716bc0dc063851
https://escholarship.org/uc/item/9g989116
https://escholarship.org/uc/item/9g989116
Autor:
Andrew J. Mannes, Michael J. Iadarola, Jenny Kim, Fernando A. Vazquez, Amelia J. Loydpierson, Dragan Maric, Mary K. Dougherty, Wallis T. Muhly, Radhika Narasimhan, Matthew R. Sapio, Taichi Goto
Publikováno v:
J Pain
During persistent pain, the dorsal spinal cord responds to painful inputs from the site of injury, but the molecular modulatory processes have not been comprehensively examined. Using transcriptomics and multiplex in situ hybridization, we identified
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::59838bba9936948827ffc42b80722634
https://europepmc.org/articles/PMC9441406/
https://europepmc.org/articles/PMC9441406/
Autor:
Guo-Fang Xue, Dongfang Li, Miao-Jing Tian, Ru-Lin Mi, Zhen-Yu Yuan, Rui-Fang Wang, Christian Hölscher
Publikováno v:
Epilepsy Research. 154:97-106
Aims Glia-mediated neuro-inflammation and oxidative stress-induced neuronal apoptosis can contribute to epileptogenesis. We have demonstrated previously that mimetics of glucagon-like peptide-1 (GLP-1), glucose-dependent insulinotropic polypeptide (G
Publikováno v:
Brain Research. 1715:41-46
Arginine-vasopressin (AVP) is believed to be positively correlated with the brain edema formation, but the underlying mechanism is still unclear. In this study, we explored the role of the V2 receptors antagonist tolvaptan on brain edema following in
Autor:
Fu-Bo Tang, Hong Wu, Hongmin Luo, Wenhua Zhang, Yu-Meng Li, Yuelong Dai, Guochen Xu, Sen Hu, Xian Shi
Publikováno v:
Acupuncture in medicine : journal of the British Medical Acupuncture Society. 39(3)
Background To investigate whether the mechanism underlying the anti-inflammatory effects of electroacupuncture (EA) at ST36 involves dopamine (DA) and its receptor and whether it is mediated by the vagus nerve in a rat model of intestinal ischaemia-r
Autor:
Rodriguez-Perez, Ana I., Sucunza, Diego, Pedrosa, Maria A., Garrido-Gil, Pablo, Kulisevsky, Jaime, Lanciego, Jose L., Labandeira-Garcia, Jose L., Universitat Autònoma de Barcelona
Publikováno v:
Neurotherapeutics
Dipòsit Digital de Documents de la UAB
Universitat Autònoma de Barcelona
r-IIB SANT PAU. Repositorio Institucional de Producción Científica del Instituto de Investigación Biomédica Sant Pau
instname
O2, repositorio institucional de la UOC
Universitat Oberta de Catalunya (UOC)
Dipòsit Digital de Documents de la UAB
Universitat Autònoma de Barcelona
r-IIB SANT PAU. Repositorio Institucional de Producción Científica del Instituto de Investigación Biomédica Sant Pau
instname
O2, repositorio institucional de la UOC
Universitat Oberta de Catalunya (UOC)
Altres ajuts: This study received funding from the Centro de Investigación Biomédica en Red Enfermedades Neurodegenerativas' intramural program (2014/01 and 2017/02), Galician Government (Xunta de Galicia, Consellería de Educación; GRC2014/002),
Autor:
Ji-Ying Zheng, Guo-Fang Xue, Rui-Fang Wang, Miao-Jing Tian, Christian Hölscher, Dongfang Li, Peng Feng
Publikováno v:
Epilepsy Research. 142:45-52
Glucagon-like peptide-1(GLP-1) is a growth factor that has neuroprotective and anti-inflammatory properties. The protease resistant GLP-1 analogue liraglutide has been shown to be neuroprotective in previous studies in animal models of Alzheimer’s
Publikováno v:
Stroke. 48:1369-1375
Background and Purpose— CD163, a receptor for hemoglobin, is involved in hemoglobin clearance after intracerebral hemorrhage (ICH). In contrast to microglial/macrophage CD163, neuronal CD163 hemoglobin has not been well studied. This study examined