Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Nicholas M. Boulis"'
Autor:
Robert E. Gross, Faical Isbaine, Matthew A. Stern, Deqiang Qiu, Nicholas M. Boulis, Jonathan Riley
Publikováno v:
World Neurosurgery. 144:e750-e765
Background Although deep brain stimulation (DBS) of the subthalamic nucleus (STN) or globus pallidus internus (GPi) is the surgical method of choice to treat the canonical symptoms of Parkinson disease, occasionally surgical sites become infected or
Publikováno v:
Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia. 77
The thoracic sympathetic chain is implicated in several disease processes including palmar hyperhidrosis and complex regional pain syndrome. These diseases are often medically refractory and require surgical treatments including sympathectomies and g
Autor:
Alex Greven, Julian L Gendreau, Muhibullah S Tora, Pavlos Texakalidis, Nicholas M. Boulis, Zhijia Liang, Razan Faraj, Thais Federici
Molecular therapeutics for use in neurodegenerative disease and traumatic injury to the central nervous system have been implemented widely in preclinical studies and clinical trials. These strategies have broadly employed both pharmacologic and vect
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::66bd80e69b651192d66025f90e031bb2
https://doi.org/10.1016/b978-0-12-818084-6.00012-x
https://doi.org/10.1016/b978-0-12-818084-6.00012-x
Autor:
Casey L. Anthony, Kaitlin Sandor, Muhibullah S Tora, Nathan Hardcastle, Kelly M. Poth, Nicholas M. Boulis, Long Di
Stem cell therapy is a topic of great interest for disorders of the central nervous system (CNS), which are associated with limited regenerative potential. These technologies have been applied in preclinical disease models and in recent clinical tria
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::49c598c01729933c6a35d7b1340c6536
https://doi.org/10.1016/b978-0-12-813997-4.00008-6
https://doi.org/10.1016/b978-0-12-813997-4.00008-6
Publikováno v:
Brain Research. 1638:88-96
The promise of stem cell regeneration has been the hope of many neurologic patients with permanent damage to the central nervous system. There are hundreds of stem cell trials worldwide intending to test the regenerative capacity of stem cells in var
Publikováno v:
Trends in Molecular Medicine. 21:504-512
Gene therapy is, potentially, a powerful tool for treating neurodegenerative diseases such as amyotrophic lateral sclerosis (ALS), spinal muscular atrophy, Parkinson's disease (PD) and Alzheimer's disease (AD). To date, clinical trials have failed to
Autor:
Jaimie M. Henderson, Jeffrey H. Kordower, Joseph Jankovic, Mark Stacy, Barton L. Guthrie, Phillip A Starr, Gordon H. Baltuch, Andres M. Lozano, Christopher D. Herzog, Tiffany L. Baumann, Ron L. Alterman, Christopher G. Goetz, Dennis A. Turner, Matthew B. Stern, Richard K. Simpson, Nicholas M. Boulis, Paul S. Larson, William J. Marks, Raymond T. Bartus, C. Warren Olanow, Kathleen L. Poston, Ray L. Watts, Stewart A. Factor, Anthony E. Lang
Publikováno v:
Annals of Neurology. 78:248-257
Objective A 12-month double-blind sham-surgery–controlled trial assessing adeno-associated virus type 2 (AAV2)-neurturin injected into the putamen bilaterally failed to meet its primary endpoint, but showed positive results for the primary endpoint
Autor:
B.J. Mader, Nicholas M. Boulis
Diseases that afflict the nervous system remain among the most difficult pathologies for clinicians to manage. Currently there are nearly 1000 clinical trials that have been launched worldwide to study motor neuron disease (MND) clinical pathologies,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a0254a8fdf043409ad6af0d17b0a65fd
https://doi.org/10.1016/b978-0-12-802257-3.00012-2
https://doi.org/10.1016/b978-0-12-802257-3.00012-2
Spinal muscular atrophy is a genetic neurodegenerative disorder affecting muscle tone and function, primarily in children. Disease onset varies from in utero to adult, and its progression and severity differ significantly among individuals. Clinician
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::912f6cc3e85fa1c564cbf9a1b34f4633
https://doi.org/10.1016/b978-0-12-802257-3.00005-5
https://doi.org/10.1016/b978-0-12-802257-3.00005-5
Autor:
B.J. Mader, Nicholas M. Boulis
The overarching aim of neuromodulation is to provide clinicians the ability to control defined neural pathways in order to effectively treat neurological disorders. Gene-based neuromodulation uses vector-mediated gene expression to modulate synaptic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4000fdd2f7f5a5893a02a1cb4f1f8cad
https://doi.org/10.1016/b978-0-12-800454-8.00009-4
https://doi.org/10.1016/b978-0-12-800454-8.00009-4