Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Chaiboonchoe, A."'
Autor:
De Meulder B; European Institute for Systems Biology and Medicine, CNRS-ENS-UCBL, EISBM, 50 Avenue Tony Garnier, 69007, Lyon, France. bdemeulder@eisbm.org., Lefaudeux D; European Institute for Systems Biology and Medicine, CNRS-ENS-UCBL, EISBM, 50 Avenue Tony Garnier, 69007, Lyon, France., Bansal AT; Acclarogen Ltd, St John's Innovation Centre, Cambridge, CB4 OWS, UK., Mazein A; European Institute for Systems Biology and Medicine, CNRS-ENS-UCBL, EISBM, 50 Avenue Tony Garnier, 69007, Lyon, France., Chaiboonchoe A; European Institute for Systems Biology and Medicine, CNRS-ENS-UCBL, EISBM, 50 Avenue Tony Garnier, 69007, Lyon, France., Ahmed H; European Institute for Systems Biology and Medicine, CNRS-ENS-UCBL, EISBM, 50 Avenue Tony Garnier, 69007, Lyon, France., Balaur I; European Institute for Systems Biology and Medicine, CNRS-ENS-UCBL, EISBM, 50 Avenue Tony Garnier, 69007, Lyon, France., Saqi M; European Institute for Systems Biology and Medicine, CNRS-ENS-UCBL, EISBM, 50 Avenue Tony Garnier, 69007, Lyon, France., Pellet J; European Institute for Systems Biology and Medicine, CNRS-ENS-UCBL, EISBM, 50 Avenue Tony Garnier, 69007, Lyon, France., Ballereau S; European Institute for Systems Biology and Medicine, CNRS-ENS-UCBL, EISBM, 50 Avenue Tony Garnier, 69007, Lyon, France., Lemonnier N; European Institute for Systems Biology and Medicine, CNRS-ENS-UCBL, EISBM, 50 Avenue Tony Garnier, 69007, Lyon, France., Sun K; Data Science Institute, Imperial College, London, SW7 2AZ, UK., Pandis I; Data Science Institute, Imperial College, London, SW7 2AZ, UK.; Janssen Research and Development Ltd, High Wycombe, HP12 4DP, UK., Yang X; Data Science Institute, Imperial College, London, SW7 2AZ, UK., Batuwitage M; Data Science Institute, Imperial College, London, SW7 2AZ, UK., Kretsos K; UCB Pharma S.A, 1420, Braine-l'Alleud, Belgium., van Eyll J; UCB Celltech, 208 Bath Road, Slough, SL13WE, UK., Bedding A; Roche Ltd, Welwyn Garden City, AL7 1TW, UK., Davison T; Janssen Research and Development Ltd, High Wycombe, HP12 4DP, UK., Dodson P; AstraZeneca Ltd, Alderley Park, Macclesfield, SK10 4TG, UK., Larminie C; Target Sciences, GlaxoSmithKline, Gunnels Wood Road, Stevenage, SG1 2NY, UK., Postle A; Faculty of Medicine, University of Southampton, Southampton, SO17 1BJ, UK., Corfield J; AstraZeneca R & D, 43150, Mölndal, Sweden.; Arateva R & D Ltd, Nottingham, NG1 1GF, UK., Djukanovic R; Faculty of Medicine, University of Southampton, Southampton, SO17 1BJ, UK., Chung KF; National Hearth and Lung Institute, Imperial College London, London, SW3 6LY, UK., Adcock IM; National Hearth and Lung Institute, Imperial College London, London, SW3 6LY, UK., Guo YK; Data Science Institute, Imperial College, London, SW7 2AZ, UK., Sterk PJ; Department of Respiratory Medicine, Academic Medical Centre, University of Amsterdam, Amsterdam, AZ1105, The Netherlands., Manta A; Research Informatics, Roche Diagnostics GmbH, 82008, Unterhaching, Germany., Rowe A; Janssen Research and Development Ltd, High Wycombe, HP12 4DP, UK., Baribaud F; Janssen Research and Development Ltd, Spring House, PA, 19002, USA., Auffray C; European Institute for Systems Biology and Medicine, CNRS-ENS-UCBL, EISBM, 50 Avenue Tony Garnier, 69007, Lyon, France. cauffray@eisbm.org.
Publikováno v:
BMC systems biology [BMC Syst Biol] 2018 May 29; Vol. 12 (1), pp. 60. Date of Electronic Publication: 2018 May 29.
Autor:
Ana R. Sousa, Anna Selby, Jeanette Bigler, Hans Bisgaard, J. Cunha, I.M. Adcock, A.C.C. Coelho, Ryan Santos Costa, Pieter-Paul Hekking, Louise Fleming, Kai Sun, Amphun Chaiboonchoe, C.V.N. Santana, P. Moura-Santos, Scott Wagers, Ratko Djukanovic, G.P. Pinheiro, G. Hedlin, J.V. de Jesus, Kian Fan Chung, Jacek Musiał, Thomas Geiser, F. Baribaud, Emília Maria Medeiros de Andrade Belitardo, L. Cardoso, Klaus Bønnelykke, Anthony D. Postle, P H Howarth, Adelmir Souza-Machado, Valmar Biao-Lima, Stephen J. Fowler, Craig E. Wheelock, Alvaro A. Cruz, Mauricio Lima Barreto, Maria Ilma Araujo, Massimo Caruso, Laurie Pahus, P. J. Cooper, Florian Singer, W.M.C. van Aalderen, Paulo Augusto Moreira Camargos, Wolfgang Seibold, Ildiko Horvath, René Lutter, P.C.A. Almeida, I. Pandis, Victoria M. Goss, Aruna T. Bansal, John H. Riley, M. Puig Valls, P. Powel, Amanda Roberts, Alexander Mazein, M. Miralpeix, I. Paixao-Araujo, B. De Meulder, Michael Boedigheimer, Isaac Suzart Gomes-Filho, Chris Compton, C. Auffray, Jamie Matthews, Diane Lefaudeux, Elena Formaggio, A.A. Cruz, L.M. Mello, Anthony V. D'Amico, A. Lima-Matos, J. Fernandes, P. J. Sterk, Clare S. Murray, Enrica Bucchioni, Andrea Meiser, D. Erzen, Roelinde Middelveld, M. van Geest, Jørgen Vestbo, Alan J. Knox, Graham Roberts, Norbert Krug, Stewart Bates, G. Santos-Lima, Maggie Davis, Stelios Pavlidis, Paul Skipp, Yike Guo, Ariane H. Wagener, E.V. Ponte, Jens M. Hohlfeld, A. Souza-Machado, M.A. Lessa, I.S. Muniz, C.S. Cruz, Nadja Hawwa Vissing, Neuza Maria Alcantara-Neves, Tim Higenbottam, Navin Rao, Dominic Burg, Sarah Masefield, Z. Weiszhart, Matthew J. Loza, J. Haughney, Simone Hashimoto, Per Bakke, B. Thornton, José Miguel Chatkin, Andrew Bush, SE Dahlen, Joost Brandsma, N. Mores, G. Praticò, Kathleen C. Barnes, Carolina Souza-Machado, Rafael Stelmach, V. Bião-Lima, Martina Gahlemann, Paolo Montuschi, T.M.O. Souza, V.S. Vasquez, Camila Alexandrina Figueiredo, P. Chanez, Eduardo Vieira Ponte, Neil Fitch, Anthony Rowe, Cecile T.J. Holweg, S.J. Wilson, K. Fichtner, Alexander Manta, Lidia Lins, Dominic E. Shaw, David Myles, Julie Corfield, B. Dahlén, Thomas Sandström, Peter J. Sterk, Ian M. Adcock, Ralf Sigmund, James P.R. Schofield, Urs Frey, Laura C. Rodrigues, Leila Denise Alves Ferreira Amorim, E.H.D. Bel, Anna James, R.A. Franco, Paula Cristina Andrade Almeida, Paul Brinkman, H. Ahmed, Veit J. Erpenbeck, Richard G. Knowles
Publikováno v:
Respiratory medicine, 161:105817. W.B. Saunders Ltd
Background Asthma prevalence is 339 million globally. ‘Severe asthma’ (SA) comprises subjects with uncontrolled asthma despite proper management. Objectives To compare asthma from diverse ethnicities and environments. Methods A cross-sectional an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1491bcad6f32c965a6ad0f8da265e17d
http://hdl.handle.net/10044/1/83995
http://hdl.handle.net/10044/1/83995
Autor:
Zala Jevnikar, Jörgen Östling, Elisabeth Ax, Jenny Calvén, Kristofer Thörn, Elisabeth Israelsson, Lisa Öberg, Akul Singhania, Laurie C.K. Lau, Susan J. Wilson, Jonathan A. Ward, Anoop Chauhan, Ana R. Sousa, Bertrand De Meulder, Matthew J. Loza, Frédéric Baribaud, Peter J. Sterk, Kian Fan Chung, Kai Sun, Yike Guo, Ian M. Adcock, Debbie Payne, Barbro Dahlen, Pascal Chanez, Dominick E. Shaw, Norbert Krug, Jens M. Hohlfeld, Thomas Sandström, Ratko Djukanovic, Anna James, Timothy S.C. Hinks, Peter H. Howarth, Outi Vaarala, Marleen van Geest, Henric Olsson, I.M. Adcock, H. Ahmed, C. Auffray, P. Bakke, A.T. Bansal, F. Baribaud, S. Bates, E.H. Bel, J. Bigler, H. Bisgaard, M.J. Boedigheimer, K. Bønnelykke, J. Brandsma, P. Brinkman, E. Bucchioni, D. Burg, A. Bush, M. Caruso, A. Chaiboonchoe, P. Chanez, F.K. Chung, C.H. Compton, J. Corfield, A. D'Amico, S.E. Dahlen, B. De Meulder, R. Djukanovic, V.J. Erpenbeck, D. Erzen, K. Fichtner, N. Fitch, L.J. Fleming, E. Formaggio, S.J. Fowler, U. Frey, M. Gahlemann, T. Geiser, V. Goss, Y. Guo, S. Hashimoto, J. Haughney, G. Hedlin, P.W. Hekking, T. Higenbottam, J.M. Hohlfeld, C. Holweg, I. Horváth, A.J. James, R. Knowles, A.J. Knox, N. Krug, D. Lefaudeux, M.J. Loza, A. Manta, J.G. Matthews, A. Mazein, A. Meiser, R.J.M. Middelveld, M. Miralpeix, P. Montuschi, N. Mores, C.S. Murray, J. Musial, D. Myles, L. Pahus, I. Pandis, S. Pavlidis, A. Postle, P. Powel, G. Praticò, N. Rao, J. Riley, A. Roberts, G. Roberts, A. Rowe, T. Sandström, J.P.R. Schofield, W. Seibold, A. Selby, D.E. Shaw, R. Sigmund, F. Singer, P.J. Skipp, A.R. Sousa, P.J. Sterk, K. Sun, B. Thornton, W.M. van Aalderen, M. van Geest, J. Vestbo, N.H. Vissing, A.H. Wagener, S.S. Wagers, Z. Weiszhart, C.E. Wheelock, S.J. Wilson
Publikováno v:
Jevnikar, Zala; Östling, Jörgen; Ax, Elisabeth; Calvén, Jenny; Thörn, Kristofer; Israelsson, Elisabeth; Öberg, Lisa; Singhania, Akul; Lau, Laurie C K; Wilson, Susan J; Ward, Jonathan A; Chauhan, Anoop; Sousa, Ana R; De Meulder, Bertrand; Loza, Matthew J; Baribaud, Frédéric; Sterk, Peter J; Chung, Kian Fan; Sun, Kai; Guo, Yike; ... (2019). Epithelial IL-6 trans-signaling defines a new asthma phenotype with increased airway inflammation. Journal of allergy and clinical immunology, 143(2), pp. 577-590. Elsevier 10.1016/j.jaci.2018.05.026
Journal of allergy and clinical immunology, 143(2), 577-590. Mosby Inc.
Jevnikar, Z, Östling, J, Ax, E, Calvén, J, Thörn, K, Israelsson, E, Öberg, L, Singhania, A, Lau, L C K, Wilson, S J, Ward, J A, Chauhan, A, Sousa, A R, De Meulder, B, Loza, M J, Baribaud, F, Sterk, P J, Chung, K F, Sun, K, Guo, Y, Adcock, I M, Payne, D, Dahlen, B, Chanez, P, Shaw, D E, Krug, N, Hohlfeld, J M, Sandström, T, Djukanovic, R, James, A, Hinks, T S C, Howarth, P H, Vaarala, O, Van Geest, M, Olsson, H, Adcock, I M, Ahmed, H, Auffray, C, Bakke, P, Bansal, A T, Baribaud, F, Bates, S, Bel, E H, Bigler, J, Bisgaard, H, Boedigheimer, M J, Bønnelykke, K, Brandsma, J, Brinkman, P, Bucchioni, E, Burg, D, Bush, A, Caruso, M, Chaiboonchoe, A, Chanez, P, Chung, F K, Compton, C H, Corfield, J, D'amico, A, Dahlen, S E, De Meulder, B, Djukanovic, R, Erpenbeck, V J, Erzen, D, Fichtner, K, Fitch, N, Fleming, L J, Formaggio, E, Fowler, S J, Frey, U, Gahlemann, M, Geiser, T, Goss, V, Guo, Y, Hashimoto, S, Haughney, J, Hedlin, G, Hekking, P W, Higenbottam, T, Hohlfeld, J M, Holweg, C, Horváth, I, James, A J, Knowles, R, Knox, A J, Krug, N, Lefaudeux, D, Loza, M J, Manta, A, Matthews, J G, Mazein, A, Meiser, A, Middelveld, R J M, Miralpeix, M, Montuschi, P, Mores, N, Murray, C S, Musial, J, Myles, D, Pahus, L, Pandis, I, Pavlidis, S, Postle, A, Powel, P, Praticò, G, Rao, N, Riley, J, Roberts, A, Roberts, G, Rowe, A, Sandström, T, Schofield, J P R, Seibold, W, Selby, A, Shaw, D E, Sigmund, R, Singer, F, Skipp, P J, Sousa, A R, Sterk, P J, Sun, K, Thornton, B, Van Aalderen, W M, Van Geest, M, Vestbo, J, Vissing, N H, Wagener, A H, Wagers, S S, Weiszhart, Z, Wheelock, C E & Wilson, S J 2018, ' Epithelial IL-6 trans-signaling defines a new asthma phenotype with increased airway inflammation ', Journal of Allergy and Clinical Immunology . https://doi.org/10.1016/j.jaci.2018.05.026
Journal of allergy and clinical immunology, 143(2), 577-590. Mosby Inc.
Jevnikar, Z, Östling, J, Ax, E, Calvén, J, Thörn, K, Israelsson, E, Öberg, L, Singhania, A, Lau, L C K, Wilson, S J, Ward, J A, Chauhan, A, Sousa, A R, De Meulder, B, Loza, M J, Baribaud, F, Sterk, P J, Chung, K F, Sun, K, Guo, Y, Adcock, I M, Payne, D, Dahlen, B, Chanez, P, Shaw, D E, Krug, N, Hohlfeld, J M, Sandström, T, Djukanovic, R, James, A, Hinks, T S C, Howarth, P H, Vaarala, O, Van Geest, M, Olsson, H, Adcock, I M, Ahmed, H, Auffray, C, Bakke, P, Bansal, A T, Baribaud, F, Bates, S, Bel, E H, Bigler, J, Bisgaard, H, Boedigheimer, M J, Bønnelykke, K, Brandsma, J, Brinkman, P, Bucchioni, E, Burg, D, Bush, A, Caruso, M, Chaiboonchoe, A, Chanez, P, Chung, F K, Compton, C H, Corfield, J, D'amico, A, Dahlen, S E, De Meulder, B, Djukanovic, R, Erpenbeck, V J, Erzen, D, Fichtner, K, Fitch, N, Fleming, L J, Formaggio, E, Fowler, S J, Frey, U, Gahlemann, M, Geiser, T, Goss, V, Guo, Y, Hashimoto, S, Haughney, J, Hedlin, G, Hekking, P W, Higenbottam, T, Hohlfeld, J M, Holweg, C, Horváth, I, James, A J, Knowles, R, Knox, A J, Krug, N, Lefaudeux, D, Loza, M J, Manta, A, Matthews, J G, Mazein, A, Meiser, A, Middelveld, R J M, Miralpeix, M, Montuschi, P, Mores, N, Murray, C S, Musial, J, Myles, D, Pahus, L, Pandis, I, Pavlidis, S, Postle, A, Powel, P, Praticò, G, Rao, N, Riley, J, Roberts, A, Roberts, G, Rowe, A, Sandström, T, Schofield, J P R, Seibold, W, Selby, A, Shaw, D E, Sigmund, R, Singer, F, Skipp, P J, Sousa, A R, Sterk, P J, Sun, K, Thornton, B, Van Aalderen, W M, Van Geest, M, Vestbo, J, Vissing, N H, Wagener, A H, Wagers, S S, Weiszhart, Z, Wheelock, C E & Wilson, S J 2018, ' Epithelial IL-6 trans-signaling defines a new asthma phenotype with increased airway inflammation ', Journal of Allergy and Clinical Immunology . https://doi.org/10.1016/j.jaci.2018.05.026
BackgroundAlthough several studies link high levels of IL-6 and soluble IL-6 receptor (sIL-6R) to asthma severity and decreased lung function, the role of IL-6 trans-signaling (IL-6TS) in asthmatic patients is unclear.ObjectiveWe sought to explore th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ab73d68f4dbf9b501c650ac563ec4c72
https://eprints.soton.ac.uk/421475/
https://eprints.soton.ac.uk/421475/
Autor:
Brandsma, J., Goss, V., Yang, X., Bakke, P. S., Caruso, M., Chanez, P., Dahlen, S. -E., Fowler, S. J., Horvath, I., Krug, N., Montuschi, P., Sanak, M., Sandstrom, T., Shaw, D. E., Chung, K. F., Singer, F., Fleming, L. J., Sousa, A. R., Pandis, I., Bansal, A. T., Sterk, P. J., Djukanovic, R., Postle, A. D., Adcock, I. M., Ahmed, H., Auffray, C., Baribaud, F., Bates, S., Bel, E. H., Bigler, J., Bisgaard, H., Boedigheimer, M. J., Bonnelykke, K., Brinkman, P., Bucchioni, E., Burg, D., Bush, A., Chaiboonchoe, A., Chung, F. K., Compton, C. H., Corfield, J., D'Amico, A., Dahlen, B., De Meulder, B., Erpenbeck, V. J., Erzen, D., Fichtner, K., Fitch, N., Formaggio, E., Frey, U., Gahlemann, M., Geiser, T., Guo, Y., Hashimoto, S., Haughney, J., Hedlin, G., Hekking, P. W., Higenbottam, T., Hohlfeld, J. M., Holweg, C., Howarth, P., James, A. J., Knowles, R. G., Knox, A. J., Lefaudeux, D., Loza, M. J., Lutter, R., Manta, A., Masefield, S., Matthews, J. G., Mazein, A., Meiser, A., Middelveld, R. J. M., Miralpeix, M., Mores, N., Murray, C. S., Musial, J., Myles, D., Pahus, L., Pavlidis, S., Powel, P., Pratico, G., Puig Valls, M., Rao, N., Riley, J., Roberts, A., Roberts, G., Rowe, A., Schofield, J. P. R., Seibold, W., Selby, A., Sigmund, R., Skipp, P. J., Sun, K., Thornton, B., van Aalderen, W. M., van Geest, M., Vestbo, J., Vissing, N. H., Wagener, A. H., Wagers, S. S., Weiszhart, Z., Wheelock, C. E., Wilson, S. J.
Publikováno v:
Metabolomics, 14(10):123. Springer New York
Metabolomics
U-BIOPRED Study Group 2018, ' Lipid phenotyping of lung epithelial lining fluid in healthy human volunteers ', Metabolomics, vol. 14, no. 10, pp. 123 . https://doi.org/10.1007/s11306-018-1412-2
Metabolomics
U-BIOPRED Study Group 2018, ' Lipid phenotyping of lung epithelial lining fluid in healthy human volunteers ', Metabolomics, vol. 14, no. 10, pp. 123 . https://doi.org/10.1007/s11306-018-1412-2
Background Lung epithelial lining fluid (ELF)—sampled through sputum induction—is a medium rich in cells, proteins and lipids. However, despite its key role in maintaining lung function, homeostasis and defences, the composition and biology of EL
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f47ec7767267c46ae3aaafec649ff047
https://ruj.uj.edu.pl/xmlui/handle/item/103625
https://ruj.uj.edu.pl/xmlui/handle/item/103625
Autor:
Pieter-Paul Hekking, Matt J. Loza, Stelios Pavlidis, Bertrand de Meulder, Diane Lefaudeux, Fred Baribaud, Charles Auffray, Ariane H. Wagener, Paul Brinkman, Rene Lutter, Aruna T. Bansal, Ana R. Sousa, Steve A. Bates, Yannis Pandis, Louise J. Fleming, Dominique E. Shaw, Stephen J. Fowler, Y. Guo, Andrea Meiser, Kai Sun, Julie Corfield, Peter H. Howarth, Elisabeth H. Bel, Ian M. Adcock, Kian Fan Chung, Ratko Djukanovic, Peter J. Sterk, I.M. Adcock, H. Ahmed, C. Auffray, P. Bakke, A.T. Bansal, F. Baribaud, S. Bates, E.H. Bel, J. Bigler, H. Bisgaard, M.J. Boedigheimer, K. Bønnelykke, J. Brandsma, P. Brinkman, E. Bucchioni, D. Burg, A. Bush, M. Caruso, A. Chaiboonchoe, P. Chanez, F.K. Chung, C.H. Compton, J. Corfield, A. D'Amico, S.E. Dahlen, B. De Meulder, R. Djukanovic, V.J. Erpenbeck, D. Erzen, K. Fichtner, N. Fitch, L.J. Fleming, E. Formaggio, S.J. Fowler, U. Frey, M. Gahlemann, T. Geiser, S. Hashimoto, J. Haughney, G. Hedlin, P.W. Hekking, T. Higenbottam, J.M. Hohlfeld, C. Holweg, I. Horváth, P. Howarth, A.J. James, R. Knowles, N. Krug, D. Lefaudeux, M.J. Loza, R. Lutter, A. Manta, S. Masefield, J.G. Matthews, A. Mazein, A. Meiser, R.J.M. Middelveld, M. Miralpeix, N. Mores, C.S. Murray, J. Musial, D. Myles, L. Pahus, I. Pandis, S. Pavlidis, P. Powel, G. Praticò, M Puig Valls, N. Rao, J. Riley, A. Roberts, G. Roberts, A. Rowe, T. Sandström, W. Seibold, A. Selby, D.E. Shaw, R. Sigmund, F. Singer, P.J. Skipp, A.R. Sousa, P.J. Sterk, K. Sun, B. Thornton, W.M. van Aalderen, M. van Geest, J. Vestbo, N.H. Vissing, A.H. Wagener, S.S. Wagers, Z. Weiszhart, C.E. Wheelock, S.J. Wilson
Publikováno v:
Journal of allergy and clinical immunology, 141(4), 1280-1290. Mosby Inc.
U-BIOPRED Study Group 2018, ' Pathway discovery using transcriptomic profiles in adult-onset severe asthma ', Journal of Allergy and Clinical Immunology, vol. 141, no. 4, pp. 1280-1290 . https://doi.org/10.1016/j.jaci.2017.06.037
Journal of Allergy and Clinical Immunology, 141(4), 1280-1290. Mosby Inc.
Hekking, P-P W, Loza, M J, Pavlidis, S, De Meulder, B, Lefaudeux, D, Baribaud, F, Auffray, C, Wagener, A H, Brinkman, P, Lutter, R, Bansal, A T, Sousa, A R, Bates, S A, Pandis, Y, Flemming, L J, Shaw, D E, Fowler, S, Meiser, A, Sun, K, Corfield, J, Howarth, P, Bel, E H, Adcock, I M, Chung, K F, Djukanovic, R & Sterk Peter, J 2017, ' Pathway discovery using transcriptomic profiles in adult-onset severe asthma ', Journal of Allergy and Clinical Immunology, vol. 141, no. 4, pp. 1280-1290 . https://doi.org/10.1016/j.jaci.2017.06.037
U-BIOPRED Study Group 2018, ' Pathway discovery using transcriptomic profiles in adult-onset severe asthma ', Journal of Allergy and Clinical Immunology, vol. 141, no. 4, pp. 1280-1290 . https://doi.org/10.1016/j.jaci.2017.06.037
Journal of Allergy and Clinical Immunology, 141(4), 1280-1290. Mosby Inc.
Hekking, P-P W, Loza, M J, Pavlidis, S, De Meulder, B, Lefaudeux, D, Baribaud, F, Auffray, C, Wagener, A H, Brinkman, P, Lutter, R, Bansal, A T, Sousa, A R, Bates, S A, Pandis, Y, Flemming, L J, Shaw, D E, Fowler, S, Meiser, A, Sun, K, Corfield, J, Howarth, P, Bel, E H, Adcock, I M, Chung, K F, Djukanovic, R & Sterk Peter, J 2017, ' Pathway discovery using transcriptomic profiles in adult-onset severe asthma ', Journal of Allergy and Clinical Immunology, vol. 141, no. 4, pp. 1280-1290 . https://doi.org/10.1016/j.jaci.2017.06.037
Background: Adult-onset severe asthma is characterized by highly symptomatic disease despite high-intensity asthma treatments. Understanding of the underlying pathways of this heterogeneous disease is needed for the development of targeted treatments
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7a1f7390120efcc86f31e253222be3f9
https://ruj.uj.edu.pl/xmlui/handle/item/125948
https://ruj.uj.edu.pl/xmlui/handle/item/125948
Autor:
David Balgoma, Paul Skipp, Amphun Chaiboonchoe, Ildiko Horvath, Anthony D. Postle, Christos Rossios, Ratko Djukanovic, Kian Fan Chung, H. Ahmed, Stephane Ballereau, Stuart G. Snowden, Ben Nicholas, Charles Auffray, Stephen J. Fowler, Craig E. Wheelock, Paolo Montuschi, Dominic Burg, Anthony Rowe, Sven-Erik Dahlén, Joost Brandsma, Victoria M. Goss, Arnaldo D'Amico, Peter J. Sterk, Ian M. Adcock
Publikováno v:
The European respiratory journal. 42(3)
Inflammatory lung diseases are highly complex in respect of pathogenesis and relationships between inflammation, clinical disease and response to treatment. Sophisticated large-scale analytical methods to quantify gene expression (transcriptomics), p
Autor:
De Meulder, Bertrand, Lefaudeux, Diane, Bansal, Aruna T, Mazein, Alexander, Chaiboonchoe, Amphun, Ahmed, Hassan, Balaur, Irina, Saqi, Mansoor, Pellet, Johann, Ballereau, Stéphane, Lemonnier, Nathanaël, Sun, Kai, Pandis, Ioannis, Yang, Xian, Batuwitage, Manohara, Kretsos, Kosmas, Van Eyll, Jonathan, Bedding, Alun, Davison, Timothy, Dodson, Paul, Larminie, Christopher, Postle, Anthony, Corfield, Julie, Djukanovic, Ratko, Chung, Kian Fan, Adcock, Ian M, Guo, Yi-Ke, Sterk, Peter J, Manta, Alexander, Rowe, Anthony, Baribaud, Frédéric, Auffray, Charles, U-BIOPRED Study Group And The ETRIKS Consortium
BACKGROUND: Multilevel data integration is becoming a major area of research in systems biology. Within this area, multi-'omics datasets on complex diseases are becoming more readily available and there is a need to set standards and good practices f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cc8b7e126c029de04c57743e3619ee1c