Zobrazeno 1 - 10
of 34
pro vyhledávání: '"James S. Ware"'
Autor:
Ravi J. Amin, Deborah Morris-Rosendahl, Mat Edwards, Upasana Tayal, Rachel Buchan, Daniel J. Hammersley, Richard E. Jones, Sabiha Gati, Zohya Khalique, Batool Almogheer, Dudley J. Pennell, Arun John Baksi, Antonis Pantazis, James S. Ware, Sanjay K. Prasad, Brian P. Halliday
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 9 (2022)
BackgroundGuidelines recommend genetic testing and cardiovascular magnetic resonance (CMR) for the investigation of dilated cardiomyopathy (DCM). However, the incremental value is unclear. We assessed the impact of these investigations in determining
Externí odkaz:
https://doaj.org/article/83451483d5b64dff9239d02b24896315
Autor:
Matthias Heinig, Michiel E. Adriaens, Sebastian Schafer, Hanneke W. M. van Deutekom, Elisabeth M. Lodder, James S. Ware, Valentin Schneider, Leanne E. Felkin, Esther E. Creemers, Benjamin Meder, Hugo A. Katus, Frank Rühle, Monika Stoll, François Cambien, Eric Villard, Philippe Charron, Andras Varro, Nanette H. Bishopric, Alfred L. George, Cristobal dos Remedios, Aida Moreno-Moral, Francesco Pesce, Anja Bauerfeind, Franz Rüschendorf, Carola Rintisch, Enrico Petretto, Paul J. Barton, Stuart A. Cook, Yigal M. Pinto, Connie R. Bezzina, Norbert Hubner
Publikováno v:
Genome Biology, Vol 18, Iss 1, Pp 1-21 (2017)
Abstract Background Genetic variation is an important determinant of RNA transcription and splicing, which in turn contributes to variation in human traits, including cardiovascular diseases. Results Here we report the first in-depth survey of heart
Externí odkaz:
https://doaj.org/article/8e7bacbcd5ca43fa9bd815bc4899b453
Autor:
Job A. J. Verdonschot, Mark R. Hazebroek, James S. Ware, Sanjay K. Prasad, Stephane R. B. Heymans
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 8, Iss 11 (2019)
Externí odkaz:
https://doaj.org/article/1603290b2efc48deb0fce6fe5dc81fa3
Autor:
Inga Voges, Amrit Lota, Resham Baruah, Paul J.R. Barton, James S. Ware, John Gregson, Sanjay K Prasad, Nicola Whiffin, Brian P Halliday, Julian W.E. Jarman, Dudley J. Pennell, Angharad M. Roberts, Michael P. Frenneaux, A. John Baksi, Rachel Buchan, Upasana Tayal, Stuart A. Cook, John G.F. Cleland
Publikováno v:
Heart. 108:619-625
ObjectiveThe effect of moderate excess alcohol consumption is widely debated and has not been well defined in dilated cardiomyopathy (DCM). There is need for a greater evidence base to help advise patients. We sought to evaluate the effect of moderat
Autor:
Antonio de Marvao, Francesca Girolami, Antonis Pantazis, Francesco Mazzarotto, A. John Baksi, James S. Ware, Kathryn A. McGurk, Iacopo Olivotto, Megan H. Hawley, Angharad M. Roberts, Sanjay K Prasad, Roddy Walsh, Elisabetta Cerbai, Paul J.R. Barton, Beatrice Boschi, Ben Statton, Soha Romeih, Leander Beekman, Elisabeth M. Lodder, Declan P. O'Regan, Matteo Beltrami, Connie R. Bezzina, Magdi H. Yacoub, Birgit Funke, Mona Allouba, Yasmine Aguib, Stuart A. Cook
Publikováno v:
Genetics in Medicine
Genetics in medicine, 23(5), 856-864. Lippincott Williams and Wilkins
Genetics in medicine, 23(5), 856-864. Lippincott Williams and Wilkins
Purpose: To characterize the genetic architecture of left ventricular noncompaction (LVNC) and investigate the extent to which it may represent a distinct pathology or a secondary phenotype associated with other cardiac diseases. Methods: We performe
Autor:
Michiel T H M Henkens, Upasana Tayal, Godelieve R.F. Claes, Arthur van den Wijngaard, Debby M.E.I. Hellebrekers, Sophie L.V.M. Stroeks, Els K. Vanhoutte, Job A J Verdonschot, Han G. Brunner, Ingrid P.C. Krapels, Stephane Heymans, James S. Ware
Publikováno v:
Genetics in Medicine, 23, 11, pp. 2186-2193
Genetics in Medicine, 23(11), 2186-2193. Nature Publishing Group
Genetics in Medicine, 23, 2186-2193
Genetics in Medicine, 23(11), 2186-2193. Nature Publishing Group
Genetics in Medicine, 23, 2186-2193
PURPOSE: Accurate interpretation of variants detected in dilated cardiomyopathy (DCM) is crucial for patient care but has proven challenging. We applied a set of proposed refined American College of Medical Genetics and Genomics/Association for Molec
Autor:
Julia Platt, Megan H. Hawley, Gabi Richard, K Thomson, Hana Zouk, James S. Ware, Wendy K. Chung, Hui Mei, Roddy Walsh, Birgit Funke, Ashley Ryan, Matthew S. Lebo, Melissa A. Kelly, Naif A.M. Almontashiri, John Garcia, Daniela Macaya, Leslie G. Biesecker, Matteo Vatta, Matthew T. Wheeler, Heather Mason-Suares, Theresa A. Grebe, Natalie Berger
Publikováno v:
Hum Mutat
Human mutation, 41(9), 1577-1587. Wiley-Liss Inc.
Human mutation, 41(9), 1577-1587. Wiley-Liss Inc.
The ACMG/AMP variant classification framework was intended for highly penetrant Mendelian conditions. While it is appreciated that clinically relevant variants exhibit a wide spectrum of penetrance, accurately assessing and expressing the pathogenici
Autor:
Upasana Tayal, Amrit Lota, John G.F. Cleland, Amal Muthumala, Michael P. Frenneaux, John Gregson, Sanjay K Prasad, Suzan Hatipoglu, Ramasamy Manivarmane, Ravi Assomull, Stuart A. Cook, Ricardo Wage, James S. Ware, Cemil Izgi, Andrew D Scott, Dudley J. Pennell, Jason Dungu, Brian P Halliday, Simon Newsome
Publikováno v:
European Journal of Heart Failure. 22:1160-1170
Aims:\ud There is an important need for better biomarkers to predict left ventricular (LV) remodelling in dilated cardiomyopathy (DCM). We undertook a comprehensive assessment of cardiac structure and myocardial composition to determine predictors of
Publikováno v:
Eur Heart J
There is increasing understanding of the genetic basis to dilated cardiomyopathy and in this review, we offer a practical primer for the practising clinician. We aim to help all clinicians involved in the care of patients with dilated cardiomyopathy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d3b643b9379a7af1dbaf1f2d9388588d
https://europepmc.org/articles/PMC8216730/
https://europepmc.org/articles/PMC8216730/
Autor:
Francesco Mazzarotto, Matthew S. Edwards, Jodie Ingles, Christopher Semsarian, Stacey Peters, James S. Ware, Ronald H. Lekanne Deprez, Petros Syrris, Rudy Celeghin, Judy Fan, Argelia Medeiros Domingo, Jessica Wang, Ray E. Hershberger, Lucas Bronicki, Kalliopi Pilichou, Laiken Peterson, Daniel P. Judge, Najim Lahrouchi, Rebecca L. Miller, Ana Morales, Tomohiko Ai, Brittney Murray, Renee Johnson, Elizabeth Jordan, J. Peter van Tintelen, Courtney Thaxton, Alexandros Protonotarios, Emily Brown, Cynthia A. James, Babken Asatryan, Palak Shah, R. Thomas Lumbers, Roddy Walsh, Olga Jarinova
Publikováno v:
Circulation, vol 144, iss 1
Jordan, Elizabeth; Peterson, Laiken; Ai, Tomohiko; Asatryan, Babken; Bronicki, Lucas; Brown, Emily; Celeghin, Rudy; Edwards, Matthew; Fan, Judy; Ingles, Jodie; James, Cynthia A; Jarinova, Olga; Johnson, Renee; Judge, Daniel P; Lahrouchi, Najim; Lekanne Deprez, Ronald H; Lumbers, R Thomas; Mazzarotto, Francesco; Medeiros Domingo, Argelia; Miller, Rebecca L; ... (2021). Evidence-Based Assessment of Genes in Dilated Cardiomyopathy. Circulation, 144(1), pp. 7-19. American Heart Association 10.1161/CIRCULATIONAHA.120.053033
Circulation, 144(1), 7-19. Lippincott Williams and Wilkins
Jordan, Elizabeth; Peterson, Laiken; Ai, Tomohiko; Asatryan, Babken; Bronicki, Lucas; Brown, Emily; Celeghin, Rudy; Edwards, Matthew; Fan, Judy; Ingles, Jodie; James, Cynthia A; Jarinova, Olga; Johnson, Renee; Judge, Daniel P; Lahrouchi, Najim; Lekanne Deprez, Ronald H; Lumbers, R Thomas; Mazzarotto, Francesco; Medeiros Domingo, Argelia; Miller, Rebecca L; ... (2021). Evidence-Based Assessment of Genes in Dilated Cardiomyopathy. Circulation, 144(1), pp. 7-19. American Heart Association 10.1161/CIRCULATIONAHA.120.053033
Circulation, 144(1), 7-19. Lippincott Williams and Wilkins
Background: Each of the cardiomyopathies, classically categorized as hypertrophic cardiomyopathy, dilated cardiomyopathy (DCM), and arrhythmogenic right ventricular cardiomyopathy, has a signature genetic theme. Hypertrophic cardiomyopathy and arrhyt