Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Alena Klochkova"'
Cholesterol deprivation induces TGFβ signaling to promote basal differentiation in pancreatic cancer
Autor:
Diana Restifo, Alena Klochkova, Neelima Shah, Ido Sloma, Rachel Chiaverelli, Linara Gabitova, Suraj Peri, Richard A. Moffitt, Emmanuelle Nicolas, Alexandra Mazitova, Kathy Q. Cai, Tiffiney R. Hartman, Edna Cukierman, Erica A. Golemis, Alana M. O’Reilly, Elizabeth Handorf, Igor Astsaturov, Janusz Franco-Barraza, Ralph Francescone
SummaryOncogenic transformation alters the metabolism of cellular nutrients to sustain tumor growth. We here define a mechanism by which modifications in cholesterol metabolism control the formation of pancreatic ductal adenocarcinoma (PDAC). Disrupt
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::501275a1cbf2e88f727507f1a817bde7
https://doi.org/10.1101/633719
https://doi.org/10.1101/633719
Autor:
Reshu Saxena, Caitlin Tice, Kishan Patel, Erika G. Karassik, Kelly A. Whelan, Henry P. Parkman, Julie Gang, Mary Grace Murray, Alena Klochkova, Timothy M. Hall, Marie Pier Tetreault, Sarah J. Ward, Daniel J. Farkas, Zachary Wilmer Reichenbach
Esophageal squamous cell carcinoma (ESCC) is among the most deadly forms of human malignancy characterized by late stage diagnosis, metastasis, therapy resistance and frequent recurrence. Clinical management of ESCC remains challenging and the diseas
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::72e2cf21d5a32911b014fe0923c63ffe
https://doi.org/10.1016/bs.acr.2019.05.004
https://doi.org/10.1016/bs.acr.2019.05.004