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pro vyhledávání: '"Richard Appleton"'
Publikováno v:
Developmental Medicine & Child Neurology. 33:884-890
The head circumferences of 64 patients with Duchenne muscular dystrophy were measured and found to be greater than those of a normal population. The patients had relative, and in 12 cases, absolute macrocephaly. 47 of the 64 patients underwent intell
Autor:
Richard Appleton, HJ Leach
Publikováno v:
Developmental Medicine & Child Neurology. 33:1117-1120
Publikováno v:
Developmental Medicine & Child Neurology. 37:682-688
Lorazepam was compared with diazepam for the treatment of acute convulsions and status epilepticus in 102 children in a prospective, open, 'odd and even dates' trial. Convulsions were controlled in 76 per cent of patients treated with a single dose o
Autor:
H Gill, Alastair G. Sutcliffe, Catherine Tuleu, Ick Wong, Richard Appleton, T Shah, Apy Tse, Paul Gringras
Publikováno v:
Developmental Medicine & Child Neurology. 50:845-849
It is sometimes necessary for the contents of medication capsules to be mixed with certain foods and drinks because children are not always able to swallow the capsules. The compatibility and short-term stability (6h) of melatonin capsules mixed in a
Autor:
Richard Appleton, Stephen Maton, Jeannine Alexander, E. A. Garofalo, Klaus Fichtner, L. LaMoreaux, Guta Murray
Publikováno v:
Developmental Medicine & Child Neurology. 43:269-273
The efficacy and safety of gabapentin as add-on therapy for refractory partial seizures in 237 children, aged 3 to 12 years were evaluated over a 6-month period. All children received gabapentin at 24 to 70 mg/kg/day. Efficacy variables included the
Autor:
Richard Appleton
Publikováno v:
Brain and Development. 23:688-691
West syndrome (WS) is commonly associated with a poor long-term outcome including a small but significant mortality, infantile spasms that are resistant to treatment, the development of other seizure types and impaired cognitive and psychosocial func
Publikováno v:
Pediatric Neurology. 25:319-324
We describe two unrelated children with almost identical clinical illnesses comprising of severe, burning dysesthesia, allodynia, hypertensive encephalopathy, and laboratory evidence of both sympathetic and parasympathetic autonomic disturbance after
Publikováno v:
Developmental Medicine & Child Neurology. 34:642-644
Horner syndrome may be caused by a neuroblastoma involving the cervical sympathetic nervous system. A two-year-old girl presented with Horner syndrome and a discrete, distant neuroblastoma, suggesting that these two conditions represent a more widesp
Autor:
Liam Dorris, Eleanor Reavey, J. Helen Cross, Gordon Forbes, Alice Jollands, Ruth Williams, Andreas Brunklaus, Bryan Lynch, Sunny Philip, John H. Livingston, Colin D. Ferrie, Ingrid E. Scheffer, Rachael Ellis, Elizabeth Lee, Mary D. King, Sameer M. Zuberi, Richard Appleton, Imelda Hughes
Publikováno v:
Developmental medicine and child neurology. 55(2)
Aim Genetic testing in the epilepsies is becoming an increasingly accessible clinical tool. Mutations in the sodium channel alpha 1 subunit (SCN1A) gene are most notably associated with Dravet syndrome. This is the first study to assess the impact of
Autor:
Richard Appleton, Louise Phillips
Publikováno v:
Developmental Medicine & Child Neurology. 46
Sleep disturbances in children with neurodevelopmental disabilities are common and frequently difficult to treat with conventional pharmacological and behavioural methods. Melatonin is a pineal hormone known to be important in the regulation of the c