Zobrazeno 1 - 10
of 39
pro vyhledávání: '"Lindon J. Eaves"'
Autor:
Lucía Colodro-Conde, Margaret J. Wright, Scott D. Gordon, Nicholas G. Martin, William L. Coventry, Lindon J. Eaves, Sarah E. Medland, Stephan Ripke, Gu Zhu, Naomi R. Wray, Baptiste Couvy-Duchesne, Enda M. Byrne, A. C. Heath, P. A. F. Madden, Grant W. Montgomery
Publikováno v:
Colodro-Conde, L, Couvy-Duchesne, B, Zhu, G, Coventry, W L, Byrne, E M, Gordon, S, Wright, M J, Montgomery, G W, Madden, P A F, Ripke, S, Eaves, L J, Heath, A C, Wray, N R, Medland, S E, Martin, N G & Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium 2018, ' A direct test of the diathesis-stress model for depression ', Molecular Psychiatry, vol. 23, no. 7, pp. 1590-1596 . https://doi.org/10.1038/mp.2017.130
The diathesis-stress theory for depression states that the effects of stress on the depression risk are dependent on the diathesis or vulnerability, implying multiplicative interactive effects on the liability scale. We used polygenic risk scores for
Autor:
Stephan Ripke, Baptiste Couvy-Duchesne, Enda M. Byrne, Andrew C. Heath, Scott D. Gordon, Nicholas G. Martin, William L. Coventry, Lucia Colodro Conde, Sarah E. Medland, Margaret J. Wright, Naomi R. Wray, Grant W. Montgomery, Pamela A. F. Madden, Lindon J. Eaves, Gu Zhu
Publikováno v:
European Neuropsychopharmacology. 29:S805-S806
Background Initially developed to explain the origins of schizophrenia in the 1960s and adapted for the study of depression in the 1980s, the diathesis-stress model states that stress may activate a diathesis or vulnerability, transforming the potent
Publikováno v:
Behavior Genetics. 45:382-393
We tested two models to identify the genetic and environmental processes underlying longitudinal changes in depression among adolescents. The first assumes that observed changes in covariance structure result from the unfolding of inherent, random in
Publikováno v:
Suicide and Life-Threatening Behavior. 42:426-436
The co-occurrence of suicidal ideation, depression, and conduct disturbance is likely explained in part by correlated genetic and environmental risk factors. Little is known about the specific nature of these associations. Structured interviews on 2,
Autor:
Judy L. Silberg, Lindon J. Eaves, Philip R. Gehrman, Lisa J. Meltzer, Melisa Moore, Michael L. Perlis, Allan I. Pack
Publikováno v:
Sleep. 34:1641-1646
STUDY OBJECTIVES Insomnia is a highly prevalent sleep disorder yet little is known about the role of genetic factors in its pathophysiology. The aim of this study was to examine the relative contributions of genetic and environmental factors in expla
Autor:
Kenneth S. Kendler, Erik K. Loken, Nancy L. Pedersen, Judy L. Silberg, Lindon J. Eaves, Christel M. Middeldorp, Chandra A. Reynolds, Paul Lichtenstein, Charles O. Gardner, Dorret I. Boomsma
Publikováno v:
Psychological Science
Psychological science, 22(10), 1343-1352. SAGE Publications Inc.
Kendler, K S, Eaves, L J, Loken, E K, Pedersen, N L, Middeldorp, C M, Reynolds, C, Boomsma, D I, Lichtenstein, P, Silberg, J & Gardner, C O 2011, ' The Impact of Environmental Experiences on Symptoms of Anxiety and Depression Across the Life Span ', Psychological Science, vol. 22, no. 10, pp. 1343-1352 . https://doi.org/10.1177/0956797611417255
Psychological Science, 22(10), 1343-1352. Sage Publications
Psychological science, 22(10), 1343-1352. SAGE Publications Inc.
Kendler, K S, Eaves, L J, Loken, E K, Pedersen, N L, Middeldorp, C M, Reynolds, C, Boomsma, D I, Lichtenstein, P, Silberg, J & Gardner, C O 2011, ' The Impact of Environmental Experiences on Symptoms of Anxiety and Depression Across the Life Span ', Psychological Science, vol. 22, no. 10, pp. 1343-1352 . https://doi.org/10.1177/0956797611417255
Psychological Science, 22(10), 1343-1352. Sage Publications
Symptoms of anxiety and depression are relatively stable over time. Can this stability be explained by genetic influences, or is it caused by the long-lasting effects of accumulating environmental experiences? To address this question, we analyzed lo
Publikováno v:
Journal of Child Psychology and Psychiatry. 51:734-744
Background: Despite the increased risk of depression and conduct problems in children of depressed parents, the mechanism by which parental depression affects their children’s behavioral and emotional functioning is not well understood. The present
Autor:
Kenneth S. Kendler, Andrew C. Heath, Michael C. Neale, Ronald C. Kessler, Ellen E. Walters, C J MacLean, Lindon J. Eaves
Publikováno v:
FOCUS. 8:459-470
Objective This study was undertaken to clarify how genetic liability and stressful life events interact in the etiology of major depression. Method Information about stressful life events and onset of major depressive episodes in the past year was co
Publikováno v:
Journal of Child Psychology and Psychiatry. 44:664-676
Background: The present study was undertaken with the goal of understanding the causes of association between substance use and both conduct disturbance (CD) and depression in adolescent boys and girls. Method: Multivariate genetic structural equatio
Publikováno v:
Journal of Child Psychology and Psychiatry. 43:1052-1063
Background: The excess of unipolar depression in females emerges in adolescence. However, studies of age effects on depression scale scores have produced divergent estimates of changes from childhood to adolescence. Method: We explored possible reaso