Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Laura Lazo"'
Autor:
Laura Lazo
Publikováno v:
Expert Review of Vaccines. 19:807-815
The induction of a functional immune response against the four viral serotypes is one of the premises for an effective vaccine against Dengue virus. This is challenging since the immunization with four antigens leads to immunologic phenomena such as
Publikováno v:
Expert Review of Vaccines. 18:161-173
Dengue fever remains as a health problem worldwide. Although Dengvaxia®, was registered in several countries, the results after the immunization of people suggest an increase of risk in non-immune persons and children younger than 9 years old. No ot
Publikováno v:
Frontiers in Immunology
Frontiers in Immunology, Vol 10 (2019)
Frontiers in Immunology, Vol 10 (2019)
Autor:
Laura Lazo, Lázaro Gil
Publikováno v:
Viral Immunology. 32:236-238
Autor:
Yadira Rodríguez, Enma Brown, Gerardo Guillén, Laura Lazo, Ernesto Marcos, Yusleidi Pérez, Iris Valdés, Melyssa Yaugel, Karem Cobas, Lisset Hermida, Edith Suzarte, Lázaro Gil
Publikováno v:
Archives of Virology. 162:2247-2256
Tetra DIIIC is a subunit vaccine candidate based on domain III of the envelope protein and the capsid protein of the four serotypes of dengue virus. This vaccine preparation contains the DIIIC proteins aggregated with a specific immunostimulatory oli
Publikováno v:
Frontiers in Immunology, Vol 10 (2019)
Frontiers in Immunology
Frontiers in Immunology
Dengue is one of the most important diseases transmitted by mosquitoes. Dengvaxia®, a vaccine registered in several countries, cannot be administered to non-immune individuals and children younger than 9 years old, due to safety reasons. There are t
Autor:
Thomas Kariuki, Prisilla Kimiti, Lucy Ochola, Gerardo Guillén, Iris Valdés, María G. Guzmán, Lázaro Gil, Ernesto Marcos, James Ndung'u, Lisset Hermida, Peris Ambala, Mayling Alvarez, Alienys Izquierdo, Laura Lazo, Rikoi Hitler, Edith Suzarte
Publikováno v:
Immunology & Cell Biology. 93:57-66
Previously, we reported the ability of the chimeric protein DIIIC-2 (domain III of the dengue envelope protein fused to the capsid protein of dengue-2 virus), to induce immunity and protection in mice, when it is highly aggregated with a non-defined
Autor:
Iris Valdés, Lázaro Gil, Thomas Kariuki, Edith Suzarte, Laura Lazo, Ernesto Marcos, Alienys Izquierdo, Guadalupe Guzmán, Peris Ambala, Gerardo Guillén, Lucy Ochola, Lisset Hermida
Publikováno v:
Virology. :70-76
The role of cellular immune response in dengue virus infection is not yet fully understood. Only few studies in murine models propose that CD8+ T-cells are associated with protection from infection and disease. At the light of recent reports about th
Autor:
María G. Guzmán, Lázaro Gil, Lisset Hermida, Laura Lazo, Aracelys Blanco, Alequis Pavón, Gerardo Guillén, Yaremis Romero, Carlos López, Iris Valdés
Publikováno v:
Acta Tropica. 124:107-112
In previous studies we reported the cloning, expression and purification of the capsid protein from Dengue-2 virus. Subsequently, we described an in vitro-assembly process for the capsid protein, which resulted in nucleocapsid-like particles (recNLPs
Autor:
Gerardo Guillén, Laura Lazo, Alienys Izquierdo, Ernesto Marcos, Lázaro Gil, Angélica García, Edith Suzarte, María G. Guzmán, Iris Valdés, Lisset Hermida, Enma Brown, Lissandra Méndez
Publikováno v:
Archives of Virology. 158:225-230
It was previously reported that DIIIC-2 (a fusion protein composed of domain III of the envelope protein and the capsid protein from dengue 2 virus), as an aggregate antigen from a partially purified preparation, induced a functional protective immun