Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Natalie, S Ryan"'
Autor:
Wojciech Michno, Srinivas Koutarapu, Rafael Camacho, Christina Toomey, Katie Stringer, Karolina Minta, Junyue Ge, Durga Jha, Julia Fernandez‐Rodriguez, Gunnar Brinkmalm, Henrik Zetterberg, Kaj Blennow, Natalie S. Ryan, Tammaryn Lashley, Jörg Hanrieder
Publikováno v:
Journal of Neurochemistry. 163:233-246
Familial British dementia (FBD) and familial Danish dementia (FDD) are autosomal dominant forms of dementia caused by mutations in the integral membrane protein 2B (ITM2B, also known as BRI2) gene. Secretase processing of mutant BRI2 leads to secreti
Autor:
Carolin Koriath, Nick C. Fox, Sarah J. Tabrizi, Jonathan D. Rohrer, Natalie S. Ryan, Jonathan M. Schott, Simon Mead, Henry Houlden, Joanna Kenny
Publikováno v:
Nature Reviews Neurology. 17:23-36
Techniques for clinical genetic testing in dementia disorders have advanced rapidly but remain to be more widely implemented in practice. A positive genetic test offers a precise molecular diagnosis, can help members of an affected family to determin
Autor:
Amanda Heslegrave, Lucía Chávez-Gutiérrez, Josef Pannee, Helen Rice, Imogen Swift, Antoinette O'Connor, Jennifer M. Nicholas, Emily Abel, Nanet Willumsen, Henrik Zetterberg, Simon Mead, Selina Wray, Nick C. Fox, Charles Arber, Chris Frost, James M. Polke, Erik Portelius, Kaj Blennow, Philip S.J. Weston, Teresa Poole, Natalie S. Ryan
Publikováno v:
Brain
In vitro studies of autosomal dominant Alzheimer’s disease implicate longer amyloid-β peptides in disease pathogenesis; however, less is known about the behaviour of these mutations in vivo. In this cross-sectional cohort study, we used liquid chr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eb18fa743001979676e88b0dddc7cfea
https://lirias.kuleuven.be/handle/123456789/679509
https://lirias.kuleuven.be/handle/123456789/679509
Autor:
Timothy J. Shakespeare, Nick C. Fox, Keir Yong, Alexandra L. Young, Ross W. Paterson, Jason D. Warren, Amelia Carton, Aida Suarez-Gonzalez, Eulogio Gil-Néciga, Basil H. Ridha, Razvan V. Marinescu, Alexander J.M. Foulkes, Ivanna M. Pavisic, Daniel C. Alexander, Sebastien Ourselin, Elizabeth K. Warrington, Neil P. Oxtoby, Natalie S. Ryan, Dilek Ocal, Manja Lehmann, Nicholas C. Firth, Catherine F. Slattery, Marc Modat, Martin N. Rossor, Gil D. Rabinovici, Silvia Primativo, Bruce L. Miller, M. Jorge Cardoso, Jonathan M. Schott, Sebastian J. Crutch
Publikováno v:
Firth, N C, Primativo, S, Marinescu, R V, Shakespeare, T J, Suarez-Gonzalez, A, Lehmann, M, Carton, A, Ocal, D, Pavisic, I, Paterson, R W, Slattery, C F, Foulkes, A J M, Ridha, B H, Gil-Néciga, E, Oxtoby, N P, Young, A L, Modat, M, Cardoso, M J, Ourselin, S, Ryan, N S, Miller, B L, Rabinovici, G D, Warrington, E K, Rossor, M N, Fox, N C, Warren, J D, Alexander, D C, Schott, J M, Yong, K X X & Crutch, S J 2019, ' Longitudinal neuroanatomical and cognitive progression of posterior cortical atrophy ', Brain, vol. 142, no. 7, pp. 2082-2095 . https://doi.org/10.1093/brain/awz136
Digital.CSIC. Repositorio Institucional del CSIC
instname
Brain : a journal of neurology, vol 142, iss 7
Brain
Digital.CSIC. Repositorio Institucional del CSIC
instname
Brain : a journal of neurology, vol 142, iss 7
Brain
In the first multicentre, international longitudinal investigation of disease progression in posterior cortical atrophy, Firth et al. reveal distinct trajectories of cognitive decline and patterns of tissue loss compared to typical Alzheimer’s dise
Autor:
Dilek Ocal, Lynn Ramsey, Natalie S. Ryan, Charlie Murphy, Lu Brown, Keir Xx Yong, Brian L. Day, Pam Hulme, Gaynor Hulme, Amy Peters, Sebastian J. Crutch, Simon Ball, Isabel Phillips, A. D. Brown, Peter Riley, Aida Suarez Gonzalez, Charlie R Harrison, Anthony J. Woods, Diego Kaski
Publikováno v:
Dementia. 17:1011-1022
The current report describes the journey from the sharing of a single, extraordinary experience during a support group conversation to the development of a novel scientific investigation of balance problems in a rarer form of dementia. The story cent
Autor:
Yoni Pertzov, Sebastian J. Crutch, Jessica D. Collins, Yuying Liang, Kirsty Lu, Masud Husain, Jennifer M. Nicholas, Natalie S. Ryan, Nick C. Fox, Philip S.J. Weston, Antoinette O'Connor, Ivanna M. Pavisic
Publikováno v:
Neuropsychologia
Visual short-term memory (VSTM) deficits including VSTM binding have been associated with Alzheimer's disease (AD) from preclinical to dementia stages, cross-sectionally. Yet, longitudinal investigations are lacking. The objective of this study was t
Autor:
Carolin A M, Koriath, Joanna, Kenny, Natalie S, Ryan, Jonathan D, Rohrer, Jonathan M, Schott, Henry, Houlden, Nick C, Fox, Sarah J, Tabrizi, Simon, Mead
Publikováno v:
Nature reviews. Neurology. 17(1)
Techniques for clinical genetic testing in dementia disorders have advanced rapidly but remain to be more widely implemented in practice. A positive genetic test offers a precise molecular diagnosis, can help members of an affected family to determin
Autor:
Tammaryn Lashley, Catherine J. Mummery, Carolin Koriath, Olaf Ansorge, Lucía Chávez-Gutiérrez, Martin N. Rossor, Nick C. Fox, Emily Abel, James M. Polke, Natalie S. Ryan, M.R. Fraser, Simon Mead, Daniel Jiménez, Antoinette O'Connor
Publikováno v:
Neurobiology of Aging. 103:137.e1-137.e5
Mutations in the Presenilin 1 (PSEN1) gene are the most common cause of autosomal dominant familial Alzheimer's disease. We report the clinical, imaging and postmortem findings of kindred carrying a novel duplication mutation (Ile168dup) in the PSEN1
Autor:
Peter R. Schofield, Bernardino Ghetti, Richard Mayeux, Adam M. Brickman, Anne M. Fagan, Reisa A. Sperling, Alison Goate, Seonjoo Lee, Clifford R. Jack, Randall J. Bateman, Stephen Correia, David M. Holtzman, Giuseppe Tosto, Atul Narkhede, Christoph Laske, Colin L. Masters, John M. Ringman, John C. Morris, Virginia Buckles, Nick C. Fox, Daniel S. Marcus, Fawad Viqar, Andrew J. Saykin, Molly E. Zimmerman, Ralph N. Martins, Tammie L.S. Benzinger, Stephen Salloway, Michael W. Weiner, Stefan Förster, Nigel J. Cairns, Natalie S. Ryan, Eric McDade
Publikováno v:
Annals of Neurology. 79:929-939
Objective White matter hyperintensities (WMHs) are areas of increased signal on T2-weighted magnetic resonance imaging (MRI) scans that most commonly reflect small vessel cerebrovascular disease. Increased WMH volume is associated with risk and progr
Publikováno v:
Brain. 138:3816-3821
It is 100 years since the death of Aloysius ‘Alois’ Alzheimer (1864–1915). In that time the disease that bears his name has gone from being considered a rare condition only affecting younger people to a major public health priority as Governmen