Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Stephen H. Bryant"'
Autor:
Renata C. Geer, Aron Marchler-Bauer, Paul A. Thiessen, Christopher J. Lanczycki, Stephen H. Bryant, Dachuan Zhang, Thomas Madej
Publikováno v:
Nucleic Acids Research
The computational detection of similarities between protein 3D structures has become an indispensable tool for the detection of homologous relationships, the classification of protein families and functional inference. Consequently, numerous algorith
Autor:
David I. Hurwitz, Christopher J. Lanczycki, Noreen R. Gonzales, Stephen H. Bryant, Farideh Chitsaz, James S. Song, Marc Gwadz, Gabriele H. Marchler, Narmada Thanki, Lewis Y. Geer, Dachuan Zhang, Renata C. Geer, Fu Lu, Chanjuan Zheng, Roxanne A. Yamashita, Myra K. Derbyshire, Aron Marchler-Bauer, Shennan Lu
Publikováno v:
Nucleic Acids Research
CDD, the Conserved Domain Database, is part of NCBI’s Entrez query and retrieval system and is also accessible via http://www.ncbi.nlm.nih.gov/Structure/cdd/cdd.shtml. CDD provides annotation of protein sequences with the location of conserved doma
Autor:
Chunlei Liu, Renata C. Geer, Kenneth J. Addess, Anna R. Panchenko, Lewis Y. Geer, Thomas Madej, Stephen H. Bryant, Aron Marchler-Bauer, Christopher J. Lanczycki, Shennan Lu, Jie Chen, Jessica H. Fong, Dachuan Zhang, Yanli Wang, Paul A. Thiessen
Publikováno v:
Nucleic Acids Research
Close to 60% of protein sequences tracked in comprehensive databases can be mapped to a known three-dimensional (3D) structure by standard sequence similarity searches. Potentially, a great deal can be learned about proteins or protein families of in
Publikováno v:
Protein Science. 15:352-361
Proteins evolved through the shuffling of functional domains, and therefore, the same domain can be found in different proteins and species. Interactions between such conserved domains often involve specific, well-determined binding surfaces reflecti
Autor:
Alejandro A. Schäffer, Stephen H. Bryant, Anna R. Panchenko, Paul A. Thiessen, Stephen F. Altschul, Maricel G. Kann
Publikováno v:
Bioinformatics (Oxford, England). 21(8)
Motivation: With the continuing rapid growth of protein sequence data, protein sequence comparison methods have become the most widely used tools of bioinformatics. Among these methods are those that use position-specific scoring matrices (PSSMs) to
Autor:
John B. Anderson, Paul A. Thiessen, David I. Hurwitz, Raja Mazumder, Natalie D. Fedorova, Jodie J. Yin, Gabriele H. Marchler, Lewis Y. Geer, Aron Marchler-Bauer, Stephen H. Bryant, John D. Jackson, Aviva R. Jacobs, James S. Song, Sona Vasudevan, Benjamin A. Shoemaker, Siqian He, Bachoti S. Rao, Anna R. Panchenko, Anastasia N. Nikolskaya, Thomas Madej, Chunlei Liu, Roxanne A. Yamashita, Cynthia A. Liebert, Vahan Simonyan, Yanli Wang, Christopher J. Lanczycki, Carol DeWeese-Scott
Publikováno v:
Nucleic acids research. 31(1)
The Conserved Domain Database (CDD) is now indexed as a separate database within the Entrez system and linked to other Entrez databases such as MEDLINE(R). This allows users to search for domain types by name, for example, or to view the domain archi
Autor:
Jie, Chen, John B, Anderson, Carol, DeWeese-Scott, Natalie D, Fedorova, Lewis Y, Geer, Siqian, He, David I, Hurwitz, John D, Jackson, Aviva R, Jacobs, Christopher J, Lanczycki, Cynthia A, Liebert, Chunlei, Liu, Thomas, Madej, Aron, Marchler-Bauer, Gabriele H, Marchler, Raja, Mazumder, Anastasia N, Nikolskaya, Bachoti S, Rao, Anna R, Panchenko, Benjamin A, Shoemaker, Vahan, Simonyan, James S, Song, Paul A, Thiessen, Sona, Vasudevan, Yanli, Wang, Roxanne A, Yamashita, Jodie J, Yin, Stephen H, Bryant
Publikováno v:
Nucleic acids research. 31(1)
Three-dimensional structures are now known within most protein families and it is likely, when searching a sequence database, that one will identify a homolog of known structure. The goal of Entrez's 3D-structure database is to make structure informa
Publikováno v:
Proteins. 48(3)
Profile search methods based on protein domain alignments have proven to be useful tools in comparative sequence analysis. Domain alignments used by currently available search methods have been computed by sequence comparison. With the growth of the