Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Yong J. Lee"'
Autor:
Yong Seok Park, Kalishwaralal Kalimuthu, Yong J. Lee, Ja Lok Ku, Jin Hong Kim, Xu Luo, Lin Zhang, M. Haroon A. Choudry
Publikováno v:
Journal of Cellular Physiology. 236:6666-6677
Abnormalities of the tumor vasculature result in insufficient blood supply and development of a tumor microenvironment that is characterized by low glucose concentrations, low extracellular pH, and low oxygen tensions. We previously reported that glu
Publikováno v:
Journal of Cellular Biochemistry. 112:118-127
The aim of this study was to investigate the effect of garlic constituent diallyl trisulfide (DATS) on the cell-death signaling pathway in a human breast cell line (MDA-MB-231). We observed that DATS (10-100 µM) treatment resulted in dose- and time-
Autor:
Marco A. Alcala, Jinsang Yoo, David L. Bartlett, Byeong-Chel Lee, Bae-Hang Park, Dae Hee Lee, Kyung Soo Park, Yong J. Lee
Publikováno v:
Journal of Cellular Biochemistry. 110:1073-1081
Approximately 25% of patients with colorectal cancer develop metastases to the liver, and surgery is currently the best treatment available. But there are several patients who are unresectable, and isolated hepatic perfusion (IHP) offers a different
Publikováno v:
Journal of Cellular Biochemistry. 104:1172-1180
Tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) is a member of the TNF superfamily. TRAIL shows strong cytotoxicity to many cancer cells but minimal cytotoxicity to most normal cells. Interestingly, our recent studies have demonstrate
Publikováno v:
Molecular Pharmacology. 62:1409-1417
We observed previously that glucose deprivation induces cytotoxicity, increases the intracellular levels of hydroperoxide, and activates the stress-activated protein kinase (SEK) pathway. In this study, we hypothesized that 1-methylpropyl 2-imidazoly
Publikováno v:
The American Journal of Pathology. 160:1069-1075
We investigated the role of galectin-3 in metastasis of human breast carcinoma BT549 cells using the experimental liver metastasis model. Underlying mechanisms were then elucidated using the liver/tumor co-culture and cell culture systems. After intr
Autor:
Jessup Jm, Kyung-Hwa Lee, Song Yk, Timothy R. Billiar, Kim Hr, Dai-Wu Seol, Yong J. Lee, Kim Th
Publikováno v:
Oncogene. 20:1476-1485
The tumor necrosis factor-related apoptosis-inducing ligand (TRAIL, Apo-2L) is a recently characterized member of the family of programmed cell death-inducing ligands that includes TNF-alpha and CD95L (FasL). It is well known that TRAIL binds to the
Autor:
Sandra Galoforo, Yong J. Lee, Lisa A. Ridnour, Julia E. Sim, Henry Jay Forman, Peter M. Corry, Douglas R. Spitz, Jinah Choi
Publikováno v:
Free Radical Biology and Medicine. 28:575-584
Signal transduction pathway involved in glucose deprivation-induced oxidative stress were investigated in human breast carcinoma cells (MCF-7/ADR). In MCF-7/ADR, glucose deprivation-induced prolonged activation of c-Jun N-terminal kinase (JNK1) as we
Autor:
Sandra Galoforo, Yong J. Lee, Robert V. Blackburn, M B S Christine Berns, Peter M. Corry, Nalini M. Motwani
Publikováno v:
Cancer. 82:1137-1145
BACKGROUND High grade gliomas represent very aggressive and lethal forms of human cancer, which often exhibit recurrence after surgical intervention and resistance to conventional chemotherapeutic and radiologic treatment. The clinically approved ant
Publikováno v:
Cancer. 75:2262-2268
Background. Several recent studies have suggested radiosensitizing effects of paclitaxel, a microtubular inhibitor. To test the universality of this finding, the interaction between paclitaxel and radiation treatment of cell lines derived from three