Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Won-Ha Lee"'
Publikováno v:
The Journal of Immunology. 204:1299-1309
LETM1 domain–containing protein 1 (LETMD1), also known as HCCR-1, is a mitochondrial protein and is known to regulate p53 and STAT3 activities in cancer cells. In this study, we present, for the first time (to our knowledge), data indicating that L
Publikováno v:
Pharmacology Research & Perspectives
Pharmacology Research & Perspectives, Vol 9, Iss 6, Pp n/a-n/a (2021)
Pharmacology Research & Perspectives, Vol 9, Iss 6, Pp n/a-n/a (2021)
Engineered G protein‐coupled receptors (GPCRs) are commonly used in chemogenetics as designer receptors exclusively activated by designer drugs (DREADDs). Although several GPCRs have been studied in astrocytes using a chemogenetic approach, the fun
Autor:
Ki Beom Bae, Na Ri Kim, Myoung Ok Kim, Hei Jung Kim, Du Hak Yoon, Si Jun Park, Young Rae Ji, Won-Ha Lee, Mi Jung Shin, Jun Koo Yi, Zae Young Ryoo, Seo Jin Park, Sanggyu Lee, Dong Hoon Yu, Hyung Soo Yuh
Publikováno v:
Biochemical and Biophysical Research Communications. 417:280-286
The T-cell receptor (TCR) engages with an antigen and initiates a signaling cascade that leads to the activation of transcription factors. Roquin, a protein encoded by the RC3H1 gene and characterized as an immune regulator, was recently identified a
Publikováno v:
Research in Veterinary Science. 89:295-300
Virus-like particles (VLPs) are particles that consist of viral capsid proteins and are structurally similar to authentic virus. To express VLPs of the porcine encephalomyocarditis virus (EMCV) and investigate their efficacy and immuno response in vi
Publikováno v:
Journal of Neurochemistry. 107:1225-1235
Glial activation and neuroinflammatory processes play an important role in the pathogenesis of neurodegenerative diseases such as Alzheimer's disease, Parkinson's disease, and HIV dementia. Activated glia cells can secrete various proinflammatory cyt
Autor:
Sang-Hyun Kim, Jiyeon Ock, Hae Chul Park, Long Tai Zheng, Jaegyu Hwang, Ho-Won Lee, Maan-Gee Lee, Won-Ha Lee, Kyoungho Suk
Publikováno v:
Neuropharmacology. 55:826-834
Glial activation and neuroinflammatory processes play an important role in the pathogenesis of neurodegenerative diseases such as Alzheimer's disease, Parkinson's disease, and HIV dementia. Activated glial cells can secrete various proinflammatory cy
Autor:
Kyoungho Suk, Eun-Mi Bae, Joo Y. Lee, Byoung S. Kwon, Hyung-Uk Bae, Won-Ha Lee, Su-Hyung Hong, Yoon-Joong Kang, Won-Jung Kim, Jeong-Euy Park
Publikováno v:
Immunology. 119:421-429
Glucocorticoid-induced tumour necrosis factor receptor family related protein (GITR) is the 18th member of the tumour necrosis factor receptor superfamily (TNFRSF18) and is known to interact with its cognate ligand GITRL (TNFSF18). We investigated th
Autor:
Won-Ha Lee, Won-Jung Kim, Yong Bok Park, Hyung-Uk Bae, Yoon-Joong Kang, Byoung S. Kwon, Dong-Ik Kim, Jeong-Euy Park
Publikováno v:
Cytokine. 29:229-235
TL1A (VEGI/TNFSF15) is the ligand for DR3 (TNFRSF12) and is a newly identified member of the tumor necrosis factor superfamily (TNFSF). Previously, DR3 has been shown to have a role in atherogenesis through stimulation of matrix degrading enzymes inc
Autor:
Mi Ae Kang, Goo Taeg Oh, Ji Young Kim, Nam Ho Jeoung, Yong Bok Park, Kyung Tak Nam, Myung-Sook Choi, Moon Kyoo Jang, Won-Ha Lee
Publikováno v:
Biochemical and Biophysical Research Communications. 323:898-905
Genes induced or suppressed by oxidized low-density lipoproteins (oxLDL) in human monocytic THP-1 cells were searched using the differential display reverse transcriptase polymerase chain reaction. One of the differentially expressed (up-regulated) c
Autor:
Won-Jung Kim, Dong-Ik Kim, Yong Bok Park, Dong-Kyun Woo, Yoon-Joong Kang, Byoung S. Kwon, Yoon Lee, Jeong-Euy Park, Se-Hwa Kim, Won-Ha Lee
Publikováno v:
Circulation Journal. 68:396-399
The expression of TWEAK (TNFSF12) and TweakR/Fn14 was detected in regions rich in macrophage/foam cells in atherosclerotic plaques. The role of TWEAK in monocytes in relation to atherogenesis was investigated by analyzing the cellular events induced