Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Marc Tebruegge"'
Autor:
Susie Germano, Justin T Denholm, Emma S. McBryde, Roy M. Robins-Browne, Lucy Cosentino, Marc Tebruegge, Vanessa Clifford, Nigel Curtis, Damon P. Eisen, Ben Forbes, Elizabeth Matchett, Alan C Street, Christel Zufferey
Publikováno v:
Tuberculosis. 114:91-102
Objective Accurate and timely diagnosis of tuberculosis (TB) is essential to control the global pandemic. Currently available immunodiagnostic tests cannot discriminate between latent tuberculosis infection (LTBI) and active tuberculosis. This study
Autor:
Marc Tebruegge, Nicole Ritz, Susan Donath, Binita Dutta, Benjamin Forbes, Vanessa Clifford, Christel Zufferey, Robert De Rose, Roy M. Robins-Browne, Willem Hanekom, Stephen M. Graham, Tom Connell, Nigel Curtis
Publikováno v:
Frontiers in Immunology, Vol 10 (2019)
Frontiers in Immunology
Frontiers in Immunology
Background: Current immune-based TB tests, including the tuberculin skin test (TST) and interferon-gamma release assays (IGRA), have significant limitations, including the inability to distinguish between latent TB infection (LTBI) and active TB. Few
Autor:
Marc Tebruegge, Paul T. Elkington
Publikováno v:
Thorax. 73(3)
The need for better diagnostics for TB has been repeated so frequently that there is a danger of message fatigue. However, the unfortunate return of TB as the number 1 cause of death due to an infectious disease must surely serve as a further call to
Autor:
Christel Zufferey, Alan C Street, Vanessa Clifford, Justin T Denholm, Nigel Curtis, Marc Tebruegge
Publikováno v:
Tuberculosis. 95:217-228
The ability to monitor response to therapy for tuberculosis (TB) and confirm adequate treatment would be a major advance. The low reversion rate of interferon-gamma based assays means that they are unlikely to be useful for monitoring therapy. Severa
Autor:
Susie Germano, David E Leslie, Alan C Street, Nigel Curtis, Christel Zufferey, Norbert Ryan, Marc Tebruegge, Vanessa Clifford, Justin T Denholm
Publikováno v:
Tuberculosis. 95:343-349
Summary Introduction The ability to monitor and confirm adequate treatment of latent TB infection (LTBI) would be a major advance. The potential immunomodulatory effects of anti-tuberculous drugs and steroids need to be considered in assessing the ut
Autor:
Tim Elliott, Joe R Fenn, Andrew Chancellor, Andrew White, Sally Sharpe, Anna S. Tocheva, Marc Tebruegge, Stephan D. Gadola, Paul T. Elkington, Salah Mansour, Akul Singhania, Mike Dennis, Liku B. Tezera
Correlates of immune protection that reliably predict vaccine efficacy against Mycobacterium tuberculosis (Mtb) infection are urgently needed. Invariant NKT cells (iNKTs) are CD1d-dependent innate T cells that augment host antimicrobial immunity thro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0058ace57dc618d5eaae3c884136c216
https://europepmc.org/articles/PMC6168056/
https://europepmc.org/articles/PMC6168056/
Autor:
Warwick J. Britton, Nicole Ritz, Susan Donath, Willem A. Hanekom, Nigel Curtis, Tom G Connell, Marc Tebruegge, Roy M. Robins-Browne, Binita Dutta, Dan Casalaz
BackgroundMore than 120 million doses of BCG vaccine are administered worldwide each year. Most infants are given BCG at birth in accordance with WHO recommendations. However, the effect of the maturing neonatal immune system on the immune response a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::00f0eabb58c86af1693228d4ee855329
https://eprints.soton.ac.uk/402103/
https://eprints.soton.ac.uk/402103/
Autor:
Nicole Ritz, Tom G Connell, Warwick J. Britton, Nigel Curtis, Roy M. Robins-Browne, Susan Donath, Binita Dutta, Dan Casalaz, Marc Tebruegge, Willem A. Hanekom
Publikováno v:
American journal of respiratory and critical care medicine. 185(2)
Approximately 100 million doses of bacille Calmette-Guérin (BCG) vaccine are given each year to protect against tuberculosis (TB). More than 20 genetically distinct BCG vaccine strains are in use worldwide. Previous studies suggest that BCG vaccine
Autor:
Nigel Curtis, Tom G Connell, Madeleine Strach, Binita Dutta, Willem A. Hanekom, Nicole Ritz, Warwick J. Britton, Carmen Yau, Roy M. Robins-Browne, Marc Tebruegge
Publikováno v:
PLoS ONE
PLoS ONE, Vol 7, Iss 7, p e37535 (2012)
PLoS One
PLoS ONE, Vol 7, Iss 7, p e37535 (2012)
PLoS One
BCG vaccine is one of the most commonly-administered vaccines worldwide. Studies suggest the protective efficacy of BCG against TB is better for children than for adults. One potential explanation is that BCG induces a better protective immune respon