Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Karen A. Fortner"'
Autor:
Felipe, Valença-Pereira, Qian, Fang, Isabelle J, Marié, Emily L, Giddings, Karen A, Fortner, Rui, Yang, Alejandro V, Villarino, Yina H, Huang, David A, Frank, Haitao, Wen, David E, Levy, Mercedes, Rincon
Publikováno v:
Proc Natl Acad Sci U S A
Interleukin 6 (IL-6) is known to regulate the CD4 T cell function by inducing gene expression of a number of cytokines through activation of Stat3 transcription factor. Here, we reveal that IL-6 strengthens the mechanics of CD4 T cells. The presence
Autor:
Yvonne M. W. Janssen-Heininger, Matthew E. Poynter, Serpil C. Erzurum, Karolyn G. Lahue, Charles G. Irvin, Karen A. Fortner, Prescott G. Woodruff, Sidra M. Hoffman, Suzy A.A. Comhair, David G. Chapman, Jonathon M. Cahoon, Vikas Anathy, Nirav R. Bhakta, Anne E. Dixon, Gurkiranjit K. Rattu, Nirav Daphtary, Minara Aliyeva
Publikováno v:
The Journal of allergy and clinical immunology. 137(3)
Background Evidence for association between asthma and the unfolded protein response is emerging. Endoplasmic reticulum resident protein 57 (ERp57) is an endoplasmic reticulum–localized redox chaperone involved in folding and secretion of glycoprot
Autor:
Ralph C. Budd, Charles G. Irvin, Wenfang Wu, Karen A. Fortner, Jennifer Q. Russell, Lisa Rinaldi, Jürg Tschopp
Publikováno v:
The Journal of Immunology. 172:4724-4732
Cellular FLIP long form (c-FLIPL) is a caspase-defective homologue of caspase-8 that blocks apoptosis by death receptors. The expression of c-FLIPL in T cells can also augment extracellular signal-regulated kinase phosphorylation after TCR ligation v
Autor:
Bikash Sahay, Ralph C. Budd, Timothy J. Sellati, Karen A. Fortner, Jennifer Q. Russell, Nicholas J. Hardin, Cuixia Shi
Publikováno v:
Infection and immunity. 79(10)
Little is known regarding the function of γδ T cells, although they accumulate at sites of inflammation in infections and autoimmune disorders. We previously observed that γδ T cells in vitro are activated by Borrelia burgdorferi in a TLR2-depend
Autor:
Nicholas J. Hardin, Ralph C. Budd, Julie Wolfe, Jennifer Q. Russell, Karen A. Fortner, Cuixia Shi, Juan Anguita
Lyme disease represents a complex response toBorrelia burgdorferithat involves both bacterial factors as well as host responses. This results in an inflammatory reaction at several sites, including the synovial lining of joints. Synovial tissues of i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f2c1f1c17ac7408ccae0a4b76ce07450
https://europepmc.org/articles/PMC1360353/
https://europepmc.org/articles/PMC1360353/
Publikováno v:
Cell Death & Disease
Mediators produced by the airway epithelium control the activation, recruitment, and survival of pulmonary dendritic cells (DC) that present antigen to CD4(+) T cells during the genesis and exacerbation of allergic asthma. The epithelial-derived acut