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of 10
pro vyhledávání: '"Rabia Hussain"'
Autor:
Zahra Hasan, Rabia Hussain, Martin E. Rottenberg, Naseem Salahuddin, Nisar Rao, Muhammad Irfan, Kiran Iqbal Masood
Publikováno v:
The Journal of Infection in Developing Countries. 8:059-066
Introduction: Expression of Suppressor of cytokine signaling (SOCS)-1 molecules is increased in patients with tuberculosis (TB). Early Secreted Antigen Target (ESAT)-6 kDa – induced IFN-γ responses indicate Mycobacterium tuberculosis infection. Th
Publikováno v:
Transactions of the Royal Society of Tropical Medicine and Hygiene. 103:581-587
Pakistan ranks eighth in terms of tuberculosis burden worldwide, with an incidence of 181/100000. The predominant genotypes of Mycobacterium tuberculosis are reported to be the Central Asian strain 1 (CAS1) and Beijing families.Mycobacteriumtuberculo
Autor:
Firdaus Shahid, Arnawaz Kaleem, Hazel M. Dockrell, Rabia Hussain, Bushra Jamil, Maqboola Dojki, Hammad Mehmood, Ghaffar Dawood
Publikováno v:
Journal of Immunological Methods. 264:95-108
Whole-blood assays (WB) provide a simple tool for assessing immune cytokine profiles which may be useful laboratory predictors of early disease, aiding the evaluation of new tuberculosis (TB) vaccines and offering insights into disease pathogenesis.
Publikováno v:
Clinical and Experimental Immunology. 123:210-218
SUMMARYCachexia is one of the prominent features of advanced tuberculosis (TB) seen in association with increased expression of the monokine TNF-α. Several mycobacterial proteins, including PPD, stimulate TNF-α secretion from monocytes. Host factor
Publikováno v:
Journal of clinical immunology. 31(5)
Dynamic cytokine profiles from endogenously activated T cells in transit from lymph node to the infected sites via the blood compartment after recent exposure to Mycobacterium tuberculosis may differentiate disease progressors from non-disease progre
Publikováno v:
Cytokine. 54(2)
Differential T cell trafficking through the blood compartment towards infected foci may be occurring in different stages of tuberculosis disease and infection. The aim of the present study was to identify cytokine signatures in the blood compartment
Household contacts (HCs) of patients with tuberculosis (TB) are at higher risk of infection as well as the development of active disease. Longitudinal tracking of antigen-specific cytokines after acute exposure may significantly advance our understan
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6735d6220ea899e445da710add68a022
https://europepmc.org/articles/PMC2168383/
https://europepmc.org/articles/PMC2168383/
SUMMARY Chronic inflammation associated with cachexia, weight loss, fever and arthralgia is the hallmark of advanced mycobacterial diseases. These symptoms are attributed to the chronic stimulation of tumour necrosis factor (TNF)-α. Mycobacterial co
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::512b6ebef048e00499a16a721af4850e
https://europepmc.org/articles/PMC1809011/
https://europepmc.org/articles/PMC1809011/
Autor:
Berit Carow, M. Islam, Martin E. Rottenberg, Zahra Hasan, Naseem Salahuddin, Kiran Iqbal Masood, Rabia Hussain, Nisar Rao, Muhammad Irfan
Publikováno v:
BMC Infectious Diseases
BMC Infectious Diseases, Vol 13, Iss 1, p 13 (2013)
BMC Infectious Diseases, Vol 13, Iss 1, p 13 (2013)
Background Appropriate immune activation of T cells and macrophages is central for the control of Mycobacterium tuberculosis infections. IFN-γ stimulated responses are lowered in tuberculosis (TB), while expression of Suppressor of Cytokine Signalin
Autor:
Javaid A Khan, Mussarat Ashraf, Rabia Hussain, Muhammad S. Yusuf, M. Islam, Bushra Jamil, Zahra Hasan
Publikováno v:
PLoS ONE
PLoS ONE, Vol 4, Iss 4, p e5158 (2009)
PLoS ONE, Vol 4, Iss 4, p e5158 (2009)
BackgroundProtective responses against Mycobacterium tuberculosis are dependent on appropriate T cell and macrophage activation. Mycobacterial antigen six kDa early secreted antigenic target (ESAT6) and culture filtrate protein 10 (CFP10) can detect