Zobrazeno 1 - 10
of 53
pro vyhledávání: '"Dao Wen Wang"'
Autor:
Bei Wang, Dao Wen Wang, Ingrid Fleming, Jiong Hu, Chen Chen, Lingli Dong, Lujin Wu, Jing Chen, Zheng Wen
Publikováno v:
Signal Transduction and Targeted Therapy, Vol 6, Iss 1, Pp 1-30 (2021)
Signal Transduction and Targeted Therapy
Signal Transduction and Targeted Therapy
The arachidonic acid (AA) pathway plays a key role in cardiovascular biology, carcinogenesis, and many inflammatory diseases, such as asthma, arthritis, etc. Esterified AA on the inner surface of the cell membrane is hydrolyzed to its free form by ph
Publikováno v:
Sheng li xue bao : [Acta physiologica Sinica]. 73(4)
The morbidity and mortality of cardiovascular diseases are increasing annually, which is one of the primary causes of human death. Recent studies have shown that epoxyeicosatrienoic acids (EETs), endogenous metabolites of arachidonic acid (AA) via CY
Publikováno v:
Molecules. 27:3873
Inflammation plays a crucial role in the initiation and development of a wide range of systemic illnesses. Epoxyeicosatrienoic acids (EETs) are derived from arachidonic acid (AA) metabolized by CYP450 epoxygenase (CYP450) and are subsequently hydroly
Publikováno v:
Advances in Nutrition. 7:1122-1128
Metabolic diseases are associated with an increased risk of developing cardiovascular disease. The features comprising metabolic diseases include obesity, insulin resistance, hyperglycemia, hyperlipidemia, and hypertension. Recent evidence has emerge
Publikováno v:
Sheng li xue bao : [Acta physiologica Sinica]. 70(6)
Kidney diseases are important causes of mortality world widely. Renal microvascular dysfunction plays a pivotal role in the development of kidney diseases. Pharmacological and biochemical tools have been used to conduct detailed studies on the metabo
Publikováno v:
Cellular Physiology and Biochemistry, Vol 39, Iss 2, Pp 721-739 (2016)
Background: Cytochrome P450 (CYP) epoxygenases metabolize arachidonic acids (AA) to form epoxyeicosatrienoic acids (EETs), which exert beneficial roles in the treatment of cardiovascular diseases, but little is known about its role on adventitial rem
Autor:
Zhihui Chen, Danli Hu, Xizhen Xu, Yan Yang, Dao Wen Wang, Ling Tu, Menglu Fu, Ruolan Dong, Ying Tang
Publikováno v:
Aging Cell
Summary Ample evidences demonstrate that cytochrome P450 epoxygenase‐derived epoxyeicosatrienoic acids (EETs) exert diverse biological activities, which include potent vasodilatory, anti‐inflammatory, and cardiovascular protective effects. In thi
Autor:
Zheng Wen, Dao Wen Wang, Ding Ai, Chenao Zhan, Chi Zhou, Jin Huang, Yi Zhu, Qing Li, Xizhen Xu, Xu Zhang
Publikováno v:
Free radical biologymedicine. 117
Chronic excessive drinking leads to myocardial contractile dysfunction and dilated cardiomyopathy, where ethanol toxicity plays an essential role. Cytochrome P450 (CYP) epoxygenases metabolize arachidonic acids to form epoxyeicosatrienoic acids (EETs
Publikováno v:
Scientific Reports
Macrophages in adipose tissue are associated with obesity-induced low-grade inflammation, which contributed to insulin resistance and the related metabolic diseases. Previous studies demonstrated the beneficial effects of epoxyeicosatrienoic acids (E
Autor:
Shaogang Wang, Zhong Chen, Ke Rao, Tao Wang, Yang Luan, Dao Wen Wang, Kai Cui, Jihong Liu, Zhe Tang
Publikováno v:
PLoS ONE
PLoS ONE, Vol 12, Iss 1, p e0170427 (2017)
PLoS ONE, Vol 12, Iss 1, p e0170427 (2017)
Our previous studies had reported that Human Tissue Kallikrein 1 (hKLK1) preserved erectile function in aged transgenic rats, while the detailed mechanism of hKLK1 protecting erectile function in aged rats through activation of cGMP and cAMP was not