Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Yingfang Liu"'
Publikováno v:
Biochemical and biophysical research communications. 526(4)
Minichromosome maintenance 8 (MCM8) is a recently identified member of the minichromosome maintenance family, which possesses helicase and ATPase activity. It interacts with MCM9 and participates in homologous recombination repair. The structure of M
Publikováno v:
Biochemical and biophysical research communications. 510(4)
AlpK is an essential monooxygenase involved in the biosynthesis of kinamycin. It catalyzes the C5-hyfroxylattion of the crucial benzo[b]-fluorence intermediate in kinamycin synthesis. However, the structure and mechanism of AlpK is unclear. Here, we
Autor:
Lu Guo, Yingfang Liu
NS1-binding protein (NS1-BP), which belongs to the Kelch protein superfamily, was first identified as a novel human 70 kDa protein that interacts with NS1 ofInfluenza A virus. It is involved in many cell functions, including pre-mRNA splicing, the ER
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d1fbb709e10a17687678cf765da87b89
https://europepmc.org/articles/PMC5947704/
https://europepmc.org/articles/PMC5947704/
Autor:
Yingfang Liu, Lei Wang, Jun Li, Wenjia Wang, Yuhui Dong, Huanhuan Li, Huanhuan Liang, Kai Yang, Chih-chen Wang, Yingbo Niu
Publikováno v:
The Journal of biological chemistry. 293(4)
Protein-disulfide isomerase-like protein of the testis (PDILT), a member of the protein-disulfide isomerase family, is a chaperone essential for the folding of spermatogenesis-specific proteins in male postmeiotic germ cells. However, the structural
Autor:
Yingfang Liu, Genhong Cheng, Feng Feng, Yao E Wang, Lingmin Yuan, Su Zeng, Huanhuan Liang, Christopher S. Crowley, Jingjing Li, Zongyang Lv
Publikováno v:
Cell Research. 23:1055-1058
Publikováno v:
The Journal of general virology. 97(9)
Orthomyxoviruses are a family of ssRNA virus, including influenza virus, infectious salmon anaemia virus and Thogoto virus. The matrix proteins of orthomyxoviruses play crucial roles in some essential processes of the viral life cycle. However, the m
Crystal structure of ISG54 reveals a novel RNA binding structure and potential functional mechanisms
Autor:
Qian Zhou, Yingfang Liu, Haiwei Chen, Hong-Bing Shu, Wen Ye, Joy Fleming, Huanhuan Liang, Zhenlin Yang, Danying Chen, Ying Li
Publikováno v:
Cell Res
Interferon-stimulated gene 56 (ISG56) family members play important roles in blocking viral replication and regulating cellular functions, however, their underlying molecular mechanisms are largely unclear. Here, we present the crystal structure of I
Publikováno v:
Protein & Cell. 3:383-391
TANK-binding kinase 1 (TBK1) is an important enzyme in the regulation of cellular antiviral effects. TBK1 regulates the activity of the interferon regulatory factors IRF3 and IRF7, thereby playing a key role in type I interferon (IFN) signaling pathw
Publikováno v:
Biochemical and Biophysical Research Communications. 410:189-194
In the nematode Caenorhabditis elegans, the cell corpse engulfment proteins CED-2, CED-5, and CED-12 act in the same pathway to regulate the activation of the Rac small GTPase, CED-10, leading to the rearrangement of the actin cytoskeleton for engulf
Autor:
Zhiyong Lou, Liang Zhang, Yu Guo, Ming Ma, Cong Zhao, Zihe Rao, Yutao Chen, Shuaiyi Liang, Shoudeng Chen, Yingfang Liu, Mark Bartlam, Xuemei Li
Publikováno v:
Journal of Virology. 83:9024-9030
Highly pathogenic influenza virus strains currently in circulation pose a significant risk of a global pandemic. Following the reported crystal structure of the endonuclease domain from the avian influenza virus polymerase PA subunit, here we report