Zobrazeno 1 - 10
of 23
pro vyhledávání: '"A. Sosinsky"'
Autor:
Sayaka Inukai, Gina E. Sosinsky, Amy Smock, Yoko Hiroaki, Angela C. Cone, Bruce J. Nicholson, Atsunori Oshima, Masoud M. Toloue, Kazutoshi Tani, Yoshinori Fujiyoshi
Publikováno v:
Journal of Molecular Biology. 405:724-735
Gap junction channels are unique in that they possess multiple mechanisms for channel closure, several of which involve the N terminus as a key component in gating, and possibly assembly. Here, we present electron crystallographic structures of a mut
Publikováno v:
Proceedings of the National Academy of Sciences. 104:10034-10039
Connexin molecules form intercellular membrane channels facilitating electronic coupling and the passage of small molecules between adjoining cells. Connexin26 (Cx26) is the second smallest member of the gap junction protein family, and mutations in
Publikováno v:
Journal of Molecular Biology. 277:171-177
Intercellular communication via gap junction membrane channels cannot occur until two apposing hemichannels (connexons) meet and dock to form a sealed cell-cell conduit. In particular, an important question is how does the structure at the extracellu
Publikováno v:
Journal of Molecular Biology. 235:1261-1270
A putative complex of the three switch proteins, FliG, FliM and FliN appears to be directly involved in torque generation and control of direction of rotation. We have developed a preparative procedure for flagellar motors that retains these proteins
Publikováno v:
Journal of Molecular Biology. 223:171-184
The Salmonella typhimurium basal body, a part of the flagellar rotary motor, consists of four rings (denoted M, S, P and L) and a coaxial rod. Using low-dose electron microscopy and image averaging methods on negatively stained and frozen-hydrated pr
Publikováno v:
Biophysical journal, vol 58, iss 5
Fourier averages of connexon images computed from low-irradiation electron micrographs of isolated negatively stained gap junction domains exhibited differences in stain distribution and connexon orientation. To analyze these polymorphic structures,
Publikováno v:
The Journal of biological chemistry. 282(12)
Gap junction channels regulate cell-cell communication by passing metabolites, ions, and signaling molecules. Gap junction channel closure in cells by acidification is well documented; however, it is unknown whether acidification affects connexins or
Autor:
Gina E. Sosinsky, Guy Perkins
Publikováno v:
Methods (San Diego, Calif.). 20(2)
Gap junctions are clusters of closely packed intercellular membrane channels embedded in the plasma membranes of two adjoining cells. The central pore of the membrane channels serves as a conduit between cell cytoplasms for molecules less than 1000 D
Publikováno v:
The Journal of Membrane Biology. 146
Gap junctions, collections of membrane channels responsible for intercellular communication, contain two paired hemichannels (also called connexons). We have investigated conditions for splitting the membrane pair using urea. We have developed a prot
The orientation of cholera toxin bound to its cell-surface receptor, ganglioside GM1, in a supporting lipid membrane was determined by electron microscopy of negatively stained toxin-lipid samples. Image analysis of two dimensional crystalline arrays
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c73a5aa4bc80aaf084f5cb22e15d4e87
https://europepmc.org/articles/PMC1275800/
https://europepmc.org/articles/PMC1275800/