Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Zihan Wu"'
Publikováno v:
Cell Discovery
Cell Discovery, Vol 7, Iss 1, Pp 1-12 (2021)
Cell Discovery, Vol 7, Iss 1, Pp 1-12 (2021)
Eukaryotic RNA polymerase I (Pol I) transcribes ribosomal DNA and generates RNA for ribosome synthesis. Pol I accounts for the majority of cellular transcription activity and dysregulation of Pol I transcription leads to cancers and ribosomopathies.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d9cf478d16bc442ed8cb13e06ca1dc04
https://doi.org/10.21203/rs.3.rs-576610/v1
https://doi.org/10.21203/rs.3.rs-576610/v1
Autor:
Yan Li, Dan Zhao, Xizi Chen, Yulei Ren, Huirong Yang, Yanhui Xu, Mo Wang, Yilun Qi, Zihan Wu, Jiabei Li, Ze Li, Haifeng Hou, Weida Liu, Zishuo Yu, Xinxin Wang
Publikováno v:
Science (New York, N.Y.). 372(6541)
Assembling for transcription initiation Eukaryotic transcription initiation by RNA polymerase II (Pol II) requires the assembly of a preinitiation complex (PIC) on core promoters. The binding of TATA box–binding protein (TBP) to the TATA box promot
Autor:
Xinxin Wang, Yanhui Xu, Zihan Wu, Zishuo Yu, Yuan Tian, Shuang He, Jie Li, Bijun Liu, Jiali Yu
Publikováno v:
Science (New York, N.Y.). 367(6480)
Architecture of human BAF complex The SWI/SNF family chromatin remodelers regulate chromatin and transcription. The protein complexes BAF and PBAF are mammalian SWI/SNF remodelers that play essential functions in diverse developmental and physiologic
Publikováno v:
Cell Research. 28:1121-1123
Autor:
Mengjie Liu, Yanhui Xu, Huirong Yang, Jiawei Wang, Zihan Wu, Hong-Wei Wang, Min Huang, Xizi Chen, Yilun Qi, Yuan Tian, Jiabei Li, Dan Zhao, Catherine C. L. Wong
Publikováno v:
Cell research. 28(5)
Mechanistic target of rapamycin (mTOR) complex 2 (mTORC2) plays an essential role in regulating cell proliferation through phosphorylating AGC protein kinase family members, including AKT, PKC and SGK1. The functional core complex consists of mTOR, m
Autor:
Qinhui Rao, Mengjie Liu, Yuan Tian, Zihan Wu, Yuhan Hao, Lei Song, Zhaoyu Qin, Chen Ding, Hong-Wei Wang, Jiawei Wang, Yanhui Xu
Publikováno v:
Cell research. 28(2)
ATR (ataxia telangiectasia-mutated and Rad3-related) protein kinase and ATRIP (ATR-interacting protein) form a complex and play a critical role in response to replication stress and DNA damage. Here, we determined the cryo-electron microscopy (EM) st