Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Preethi Sankaran"'
Autor:
Suhasini Iyer, Kaitlyn Loughlin, Andrew Boudreau, Dennis M. Ho, Laura Davison, Preethi Sankaran, Udaya Rangaswamy, Sharon Hartstein, Nicole S. Allen, Brian Avanzino, Harbani Kaur Malik-Chaudhry, Aarti Balasubramani, Ute Schellenberger, Karen Chang, Roland Buelow, Maria-Cristina Cuturi, Nathan D. Trinklein, Harish Medlari Basappa, Ghenima Ahmil, Kyle J. Lorentsen, Katherine E. Harris
Publikováno v:
Scientific Reports
Scientific Reports, Vol 11, Iss 1, Pp 1-15 (2021)
Scientific Reports, Vol 11, Iss 1, Pp 1-15 (2021)
The use of recombinant interleukin-2 (IL-2) as a therapeutic protein has been limited by significant toxicities despite its demonstrated ability to induce durable tumor-regression in cancer patients. The adverse events and limited efficacy of IL-2 tr
Autor:
Starlynn C, Clarke, Biao, Ma, Nathan D, Trinklein, Ute, Schellenberger, Michael J, Osborn, Laure-Hélène, Ouisse, Andrew, Boudreau, Laura M, Davison, Katherine E, Harris, Harshad S, Ugamraj, Aarti, Balasubramani, Kevin H, Dang, Brett, Jorgensen, Heather Anne N, Ogana, Duy T, Pham, Payal P, Pratap, Preethi, Sankaran, Ignacio, Anegon, Wim C, van Schooten, Marianne, Brüggemann, Roland, Buelow, Shelley, Force Aldred
Publikováno v:
Frontiers in Immunology, Vol 9 (2019)
Frontiers in Immunology
Frontiers in Immunology, 2019, 9, pp.3037. ⟨10.3389/fimmu.2018.03037⟩
Frontiers in Immunology
Frontiers in Immunology, 2019, 9, pp.3037. ⟨10.3389/fimmu.2018.03037⟩
International audience; Heavy chain-only antibodies (HCAbs) do not associate with light chains and their V H regions are functional as single domains, forming the smallest active antibody fragment. These V[H] regions are ideal building blocks for a v