Zobrazeno 1 - 10
of 38
pro vyhledávání: '"Michael T. Williams"'
Autor:
Sarah A. Jablonski, Robyn M. Amos-Kroohs, Anna C. Barnes, Michael T. Williams, Arnold Gutierrez, Charles V. Vorhees
Publikováno v:
ACS Chemical Neuroscience. 8:1479-1489
Severe stress potentiates methamphetamine (MA) neurotoxicity. However, whether moderate stress increases or decreases the neurotoxic effects of MA is unknown. We assessed the effects of MA (4 × 10 mg/kg at 2 h intervals) in combination with prior ba
Publikováno v:
Neurotoxicity Research. 31:269-282
Neonatal exposure to methamphetamine (MA) and developmental chronic stress significantly alter neurodevelopmental profiles that show a variety of long-term physiological and behavioral effects. In the current experiment, Sprague-Dawley rats were expo
Autor:
Sandra P. Zoubovsky, Jay Schulkin, Louis J. Muglia, Michael T. Williams, Shivani Tumukuntala, Charles V. Vorhees, Sarah Hoseus
Publikováno v:
Translational Psychiatry
Translational Psychiatry, Vol 10, Iss 1, Pp 1-13 (2020)
Translational Psychiatry, Vol 10, Iss 1, Pp 1-13 (2020)
Postpartum depression (PPD) affects up to 20% of mothers and has negative consequences for both mother and child. Although exposure to psychosocial stress during pregnancy and abnormalities in the hypothalamic pituitary adrenal (HPA) axis have been l
Autor:
Michael T. Williams, Curtis E. Grace, Matthew R. Skelton, Robyn M. Amos-Kroohs, Devon L. Graham, Charles V. Vorhees, Tori L. Schaefer, Amanda A. Braun
Publikováno v:
NeuroToxicology. 54:22-33
The level of lead (Pb) exposure in children has decreased dramatically since restrictions on its use were implemented. However, even with restrictions, children are exposed to Pb and still present with cognitive and behavioral deficits. One prominent
Autor:
Devon L. Graham, Michael Aschner, Keith M. Erikson, Amanda A. Braun, Matthew R. Skelton, Curtis E. Grace, Charles V. Vorhees, Robyn M. Amos-Kroohs, Tori L. Schaefer, Michael T. Williams
Publikováno v:
Toxicology Reports
Toxicology Reports, Vol 1, Iss C, Pp 1046-1061 (2014)
Toxicology Reports, Vol 1, Iss C, Pp 1046-1061 (2014)
Developmental exposure to manganese (Mn) or stress can each be detrimental to brain development. Here, Sprague-Dawley rats were exposed to two housing conditions and Mn from postnatal day (P)4–28. Within each litter two males and two females were a
Autor:
Tori L. Schaefer, Ann M. Hemmerle, Charles V. Vorhees, Nicole R. Herring, Jonathan W. Dickerson, Michael T. Williams, Kim B. Seroogy
Publikováno v:
The Journal of Comparative Neurology. 520:2459-2474
(±)3,4-Methylenedioxymethamphetamine (MDMA), a widely used drug of abuse, rapidly reduces serotonin levels in the brain when ingested or administered in sufficient quantities, resulting in deficits in complex route-based learning, spatial learning,
Effects of neonatal methamphetamine treatment on adult stress-induced corticosterone release in rats
Autor:
Curtis E. Grace, Charles V. Vorhees, Michael T. Williams, Nicole R. Herring, Tori L. Schaefer
Publikováno v:
Neurotoxicology and Teratology. 34:136-142
In rats, neonatal (+)-methamphetamine (MA) exposure and maternal separation stress increase corticosterone during treatment and result in learning and memory impairments later in life. Early-life stress also changes later responses to acute stress. W
Autor:
Michael T. Williams, Curtis E. Grace, Devon L. Graham, Tori L. Schaefer, Matthew R. Skelton, Peter H. Tang, Amanda A. Braun, Charles V. Vorhees
Publikováno v:
International Journal of Developmental Neuroscience. 29:45-55
Despite restrictions, exposure to lead (Pb) continues. Moreover, exposure varies and is often higher in lower socioeconomic status (SES) families and remains a significant risk to cognitive development. Stress is another risk factor. Lower SES may be
Autor:
Hongyan Zhu, Marc E. Rothenberg, George D. Yancopoulos, Charles V. Vorhees, Melissa McBride, Melissa K. Mingler, Michael T. Williams, Andrew J. Murphy, David M. Valenzuela
Publikováno v:
Psychoneuroendocrinology. 35:1119-1132
NPSR1 is a G protein coupled receptor expressed in multiple brain regions involved in modulation of stress. Central administration of NPS, the putative endogenous ligand of NPSR1, can induce hyperlocomotion, anxiolytic effects and activation of the H
Autor:
Devon L. Graham, Matthew R. Skelton, Michael T. Williams, Charles V. Vorhees, Curtis E. Grace, Tori L. Schaefer
Publikováno v:
International Journal of Developmental Neuroscience. 28:331-342
Neonatal rat methamphetamine (MA) exposure has been shown to cause long-term behavioral impairments similar to some of those observed following neonatal stress. The mechanism by which MA induces impairments is unknown but may be related to early incr