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pro vyhledávání: '"Claudia Kathe"'
Autor:
Claudia Kathe, Lawrence D. F. Moon
Publikováno v:
Data in Brief, Vol 21, Iss, Pp 377-385 (2018)
Data in Brief
Data in Brief
Unilateral or bilateral corticospinal tract injury in the medullary pyramids in adult rats causes anatomical and physiological changes in proprioceptive neurons projecting to the cervical spinal cord accompanied by hyperreflexia and abnormal behaviou
Autor:
Lawrence D. F. Moon, Claudia Kathe
Unilateral or bilateral corticospinal tract injury in the pyramids of adult rats causes changes in proprioceptive axon terminal arborization in the cervical spinal cord accompanied by hyperreflexia and abnormal movements including spasms [1, 2]. Trea
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b235308c4c012c3fc3e5533f3460064b
Publikováno v:
Gene Therapy. 23:231-236
Adeno-associated viral (AAV) vectors are one of the most promising gene delivery systems to the central nervous system. We now report, that AAV1 can be used to express transgenes trans-neuronally in neurons distant from the injection site. Specifical
Publikováno v:
eLife, Vol 5 (2016)
eLife
Kathe, C, Hutson, T H, McMahon, S B & Moon, L D F 2016, ' Intramuscular Neurotrophin-3 normalizes low threshold spinal reflexes, reduces spasms and improves mobility after bilateral corticospinal tract injury in rats ', eLife, vol. 5, e18146, pp. 1-30 . https://doi.org/10.7554/eLife.18146
eLife
Kathe, C, Hutson, T H, McMahon, S B & Moon, L D F 2016, ' Intramuscular Neurotrophin-3 normalizes low threshold spinal reflexes, reduces spasms and improves mobility after bilateral corticospinal tract injury in rats ', eLife, vol. 5, e18146, pp. 1-30 . https://doi.org/10.7554/eLife.18146
Brain and spinal injury reduce mobility and often impair sensorimotor processing in the spinal cord leading to spasticity. Here, we establish that complete transection of corticospinal pathways in the pyramids impairs locomotion and leads to increase
Autor:
Harold D Shine, Stephen B. McMahon, Claudia Kathe, Qin Chen, Lawrence D. F. Moon, Thomas H. Hutson
Publikováno v:
Journal of Visualized Experiments : JoVE
The corticospinal tract (CST) can be completely severed unilaterally in the medullary pyramids of the rodent brainstem. The CST is a motor tract that has great importance for distal muscle control in humans and, to a lesser extent, in rodents. A unil