Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Archana Thakur"'
Autor:
Thakur, Archana, PhD, Archana Thakur1, MSc, Mei Lang Xue1, MSc, Wen Wang1, Md, Andrew Lloyd2, Md, Denis Wakefield2, PhD, Mark Dp Willcox1
Publikováno v:
Clinical & Experimental Ophthalmology. Jun2001, Vol. 29 Issue 3, p179-182. 4p.
Autor:
Linda D. Hazlett, Sharon A. McClellan, Archana Thakur, X. Huang, Christopher Goshgarian, Ronald P. Barrett
Publikováno v:
Ocular Immunology and Inflammation. 13:279-288
Purpose: This study determined the role of inducible nitric oxide synthase (iNOS) and nitric oxide (NO) in the resistance response of BALB/c mice to P. aeruginosa-induced keratitis. Methods: RT-PCR, nitrite detection, iNOS inhibition, ELISA, and immu
Publikováno v:
Immunology & Cell Biology. 80:323-327
Pseudomonas aeruginosa ocular infection causes extensive corneal neovascularization. The purpose of the present study was to investigate the role of the angiogenic factors macrophage inflammatory protein-2 (MIP-2) and vascular endothelial growth fact
Publikováno v:
Clinical and Experimental Ophthalmology. 29:171-174
Pseudomonas aeruginosa is a virulent pathogen and is frequently associated with bacterial keratitis. Recent studies have shown that high levels of interleukin (IL)-1beta and macrophage inflammatory protein-2 are associated with the severity of cornea
Autor:
Archana Thakur, Mark D. P. Willcox
Publikováno v:
Experimental Eye Research. 70:255-259
Contact lens wear has been associated with an increased risk of corneal infection and/or inflammation. We studied the hypothesis that contact lens wear alters the number of polymorphonuclear leukocytes (PMNs) on the cornea during sleep and the levels
Autor:
Mark D. P. Willcox, Nerida Cole, Denis Wakefield, Andrew R. Lloyd, Meilang Xue, Archana Thakur, Fiona Stapleton
Publikováno v:
Immunology and cell biology. 85(7)
While the role of CC chemokines in mononuclear cell trafficking and activation has been well studied, the functional role of CC chemokines in the regulation of polymorphonuclear neutrophil (PMN) recruitment in vivo has not been widely examined. Bacte
Autor:
Alan J. Husband, Nerida Cole, Mark D. P. Willcox, Shamila Khan, Mark B. Krockenberger, Emma B.H. Hume, Archana Thakur
Publikováno v:
Current eye research. 30(7)
Purpose: To determine the contribution of interleukin-4 (IL-4) to the initial host response during corneal infection with Pseudomonas aeruginosa in a mouse model. Methods: Corneas of 6− to 8-week-old IL-4−/− and wild-type mice were topically ch
Publikováno v:
Current eye research. 29(4-5)
Antibody neutralization studies have shown that in Pseudomonas aeruginosa corneal infection, IL-1 beta is critical to regulation of the host inflammatory response, but mechanisms remain undetermined. To elucidate these mechanisms, caspase-1 knockout
Publikováno v:
Investigative ophthalmologyvisual science. 45(9)
Purpose To test an inhibitor of IL-1beta converting enzyme (ICE), with or without ciprofloxacin, in a C57BL/6 mouse model of keratitis induced by Pseudomonas aeruginosa in which corneal perforation is expected. Methods Clinical score, histopathology,
Autor:
Nick Di Girolamo, Archana Thakur, Andrew R. Lloyd, Meilang Xue, Nerida Cole, Mark D. P. Willcox, Denis Wakefield
Publikováno v:
Investigative ophthalmologyvisual science. 44(5)
Purpose This study was conducted to investigate the role of IL-1beta in the regulation of matrix metalloproteinases (MMPs) and tissue inhibitors of metalloproteinases (TIMPs) in a mouse model of experimental keratitis and corneal injury. Methods Mice