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Publikováno v:
J Am Chem Soc
We report DNA-scaffolded synergistic catalysis, a concept that combines the diverse reaction scope of synergistic catalysis with the ability of DNA to precisely pre-organize abiotic groups and undergo stimuli-triggered conformational changes. As an i
Autor:
Flóra Jozefíková, Spyros Perontsis, Katarína Koňáriková, Ľubomír Švorc, Milan Mazúr, George Psomas, Ján Moncol
Publikováno v:
Journal of inorganic biochemistry. 228
Through the reaction of copper(II) acetate with nicotinamide (pyridine-3-carboxylic acid amide, niacinamide) and some derivatives of N-phenylanthranilic acid (fenamates), seven new mixed-ligand copper(II) compounds were isolated: [Cu(tolf-O)(tolf-O,O
Publikováno v:
Computational Biology and Chemistry. 80:244-248
Theoretical studies on DNA-cleavage and DNA-binding properties of a series of Cu(II) complexes [Cu(bimda)(diimine)] 1-5 have been carried out by density functional theory (DFT). The optimized structures of Cu(II) complexes were docked into parallel,
Publikováno v:
Journal of Inorganic Biochemistry. 194:223-232
Cu(II) complexes of bis(2-benzimidazolyl) ligands connected by different linker moieties (disulfide, ethylene, ortho-phenylene) were applied in DNA cleavage reactions. Hydroxyl radicals and hydrogen peroxide were proven as reactive oxygen species (RO
Autor:
Yulong An, Andrew J Little, Peng Xuanjia, Wenji Su, Xiaodong Shi, Eric C. Breinlinger, Yang Hongfang, Duanchen Ding, Weiren Cui, Kuai Letian, Matthew P. Webster, Qu Yi, Jiangong Wang, Huanan Wen, Meng Zhao, Alexander L. Satz, Li Ke
Publikováno v:
Bioconjugate chemistry. 31(9)
We report a DNA-compatible protocol for synthesizing amides from DNA-bound aldehydes and non-nucleophilic arylamines including aza-substituted anilines, 2-aminobenzimidazoles, and 3-aminopyrazoles. The reactions were carried out at room temperature a
Autor:
Rumasha N T, Kankanamage, Abhisek Brata, Ghosh, Di, Jiang, Karmel, Gkika, Tia, Keyes, Laura A, Achola, Steven, Suib, James F, Rusling
Publikováno v:
Chem Res Toxicol
Nitrosamine metabolites resulting from cigarette smoking and E-cigarette (E-cig) vaping cause DNA damage that can lead to genotoxicity. While DNA adducts of metabolites of nitrosamines 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) and N-nitros
Autor:
Nithya Balakrishnan, Ananda Krishnan Dhanabalan, Sijia Sun, Nattamai Bhuvanesh, Suresh Awale, Jebiti Haribabu, Ramasamy Karvembu, Srividya Swaminathan, Dya Fita Dibwe
Publikováno v:
Dalton transactions (Cambridge, England : 2003). 49(27)
The reactions of CuCl2·2H2O with chromone thiosemicarbazone ligands containing a -H or -CH3 substituent on terminal N yielded monometallic Cu(ii) complexes [Cu(HL1)Cl2] (1) and [Cu(HL2)Cl2] (2), whereas bimetallic Cu(ii) complexes [Cu(μ-Cl)(HL3)]2C
Autor:
Teresa Lauria, Samuele Stazzoni, Andrew Kellett, Markus Müller, Vickie McKee, Antony Crisp, Creina Slator, Thomas Carell
Publikováno v:
Lauria, T, Slator, C, McKee, V, Müller, M, Stazzoni, S, Crisp, A L, Carell, T & Kellett, A 2020, ' A Click Chemistry Approach to Developing Molecularly Targeted DNA Scissors ', Chemistry-A European Journal, vol. 26, no. 70, pp. 16782-16792 . https://doi.org/10.1002/chem.202002860
Nucleic acid click chemistry was used to prepare a family of chemically modified triplex forming oligonucleotides (TFOs) for application as a new gene-targeted technology. Azide-bearing phenanthrene ligands—designed to promote triplex stability and
Autor:
Jiyoon Cho, Min-Sik Kim, Chang Ha Lee, Dongwon Cha, Hye-Jin Lee, Taewan Kim, Erwin Jongwoo Park
Publikováno v:
Journal of hazardous materials. 400
The microbial inactivation by cupric ion (Cu(II)) in combination with hydrogen peroxide (H2O2) and hydroxylamine (HA) was investigated for twelve different microorganisms (five Gram-negative bacteria, three Gram-positive bacteria, and four bacterioph
Publikováno v:
ACS applied materialsinterfaces. 12(15)
In this work, a lab-on-paper cathode photoelectrochemical (PEC) sensing platform was constructed for ultrasensitive microRNA-141 (miRNA-141) assay using cascaded multiple photo-active structures as signal generators and hemin/Pt nanoparticle (Pt NP)