Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Sigurdis Haraldsdottir"'
Autor:
Elizabeth K Bancroft, Elizabeth C Page, Mark N Brook, Sarah Thomas, Natalie Taylor, Jennifer Pope, Jana McHugh, Ann-Britt Jones, Questa Karlsson, Susan Merson, Kai Ren Ong, Jonathan Hoffman, Camilla Huber, Lovise Maehle, Eli Marie Grindedal, Astrid Stormorken, D Gareth Evans, Jeanette Rothwell, Fiona Lalloo, Angela F Brady, Marion Bartlett, Katie Snape, Helen Hanson, Paul James, Joanne McKinley, Lyon Mascarenhas, Sapna Syngal, Chinedu Ukaegbu, Lucy Side, Tessy Thomas, Julian Barwell, Manuel R Teixeira, Louise Izatt, Mohnish Suri, Finlay A Macrae, Nicola Poplawski, Rakefet Chen-Shtoyerman, Munaza Ahmed, Hannah Musgrave, Nicola Nicolai, Lynn Greenhalgh, Carole Brewer, Nicholas Pachter, Allan D Spigelman, Ashraf Azzabi, Brian T Helfand, Dorothy Halliday, Saundra Buys, Teresa Ramon y Cajal, Alan Donaldson, Kathleen A Cooney, Marion Harris, John McGrath, Rosemarie Davidson, Amy Taylor, Peter Cooke, Kathryn Myhill, Matthew Hogben, Neil K Aaronson, Audrey Ardern-Jones, Chris H Bangma, Elena Castro, David Dearnaley, Alexander Dias, Tim Dudderidge, Diana M Eccles, Kate Green, Jorunn Eyfjord, Alison Falconer, Christopher S Foster, Henrik Gronberg, Freddie C Hamdy, Oskar Johannsson, Vincent Khoo, Hans Lilja, Geoffrey J Lindeman, Jan Lubinski, Karol Axcrona, Christos Mikropoulos, Anita V Mitra, Clare Moynihan, Holly Ni Raghallaigh, Gad Rennert, Rebecca Collier, Judith Offman, Zsofia Kote-Jarai, Rosalind A Eeles, Lisa Adams, Julian Adlard, Rosa Alfonso, Saira Ali, Angela Andrew, Luís Araújo, Nazya Azam, Darran Ball, Queenstone Barker, Alon Basevitch, Barbara Benton, Cheryl Berlin, Nicola Bermingham, Leah Biller, Angela Bloss, Matilda Bradford, Nicola Bradshaw, Amy Branson, Charles Brendler, Maria Brennan, Barbara Bulman, Lucy Burgess, Declan Cahill, Alice Callard, Nuria Calvo Verges, Marta Cardoso, Vanda Carter, Mario Catanzaro, Anthony Chamberlain, Cyril Chapman, Michael Chong, Caroline Clark, Virginia Clowes, Lyn Cogley, Trevor Cole, Cecilia Compton, Tom Conner, Sandra Cookson, Philip Cornford, Philandra Costello, Laura Coulier, Michaela Davies, Christopher Dechet, Bianca DeSouza, Gemma Devlin, Fiona Douglas, Emma Douglas, Darshna Dudakia, Alexis Duncan, Natalie Ellery, Sarah Everest, Sue Freemantle, Mark Frydenberg, Debbie Fuller, Camila Gabriel, Madeline Gale, Lynda Garcia, Simona Gay, Elena Genova, Angela George, Demetra Georgiou, Alexandra Gisbert, Margaret Gleeson, Wayne Glover, Vincent Gnanapragasam, Sally Goff, David Goldgar, Nuno Gonçalves, Selina Goodman, Jennifer Gorrie, Hannah Gott, Anna Grant, Catherine Gray, Julie Griffiths, Karin Gupwell, Jana Gurasashvili, Eldbjørg Hanslien, Sigurdis Haraldsdottir, Rachel Hart, Catherine Hartigan, Lara Hawkes, Tricia Heaton, Alex Henderson, Rui Henrique, Kathrine Hilario, Kathryn Hill, Peter Hulick, Clare Hunt, Melanie Hutchings, Rita Ibitoye, Thomas Inglehearn, Joanna Ireland, Farah Islam, Siti Ismail, Chris Jacobs, Denzil James, Sharon Jenkins, Irene Jobson, Anne Johnstone, Oliver Jones, Sagi Josefsberg Ben-Yehoshua, Beckie Kaemba, Karen Kaul, Zoe Kemp, Netty Kinsella, Margaret Klehm, Roger Kockelbergh, Kelly Kohut, Monika Kosicka-Slawinska, Anjana Kulkarni, Pardeep Kumar, Jimmy Lam, Mandy LeButt, Dan Leibovici, Ramona Lim, Lauren Limb, Claire Lomas, Mark Longmuir, Consol López, Tiziana Magnani, Sofia Maia, Jessica Maiden, Alison Male, Merrie Manalo, Phoebe Martin, Donna McBride, Michael McGuire, Romayne McMahon, Claire McNally, Terri McVeigh, Ehud Melzer, Mark Mencias, Catherine Mercer, Gillian Mitchell, Josefina Mora, Catherine Morton, Cathryn Moss, Morgan Murphy, Declan Murphy, Shumi Mzazi, Maria Nadolski, Anna Newlin, Pedro Nogueira, Rachael O'Keefe, Karen O'Toole, Shona O'Connell, Chris Ogden, Linda Okoth, Jorge Oliveira, Edgar Paez, Joan Palou, Linda Park, Nafisa Patel, João Paulo Souto, Allison Pearce, Ana Peixoto, Kimberley Perez, Lara Petelin, Gabriella Pichert, Charlotte Poile, Alison Potter, Nadia Preitner, Helen Purnell, Ellen Quinn, Paolo Radice, Brigette Rankin, Katie Rees, Caroline Renton, Kate Richardson, Peter Risby, Jason Rogers, Maggie Ruderman, April Ruiz, Anaar Sajoo, Natale Salvatore, Victoria Sands, Francesco Sanguedolce, Ayisha Sattar, Kathryn Saunders, Lyn Schofield, Rodney Scott, Anne Searle, Ravinder Sehra, Christina Selkirk, Kylie Shackleton, Sue Shanley, Adam Shaw, Daniel Shevrin, Hannah Shipman, Zahirah Sidat, Kas Siguake, Kate Simon, Courtney Smyth, Lesley Snadden, Nita Solanky, Joyce Solomons, Margherita Sorrentino, Barbara Stayner, Robert Stephenson, Elena Stoffel, Maggie Thomas, Alan Thompson, Lizzie Tidey, Marc Tischkowitz, Audrey Torokwa, Sharron Townshend, Katy Treherne, Karen Tricker, Quoc-Dien Trinh, Vishakha Tripathi, Clare Turnbull, Riccardo Valdagni, Nicholas Van As, Vickie Venne, Lizzie Verdon, Marco Vitellaro, Kristen Vogel, Lisa Walker, Amy Watford, Cathy Watt, Ilana Weintroub, Shelly Weiss, Scott Weissman, Michelle Weston, Jennifer Wiggins, Gillian Wise, Christopher Woodhouse, Pembe Yesildag, Alice Youngs, Matthew Yurgelun, Fabiana Zollo
Publikováno v:
Bancroft, EK, Page, EC, Brook, MN, Thomas, S, Taylor, N, Pope, J, McHugh, J, Jones, AB, Karlsson, Q, Merson, S, Ong, KR, Hoffman, J, Huber, C, Maehle, L, Eeles, RA & Evans, D G 2021, ' A prospective prostate cancer screening programme for men with pathogenic variants in mismatch repair genes (IMPACT): initial results from an international prospective study. ', The Lancet. Oncology, vol. 22, no. 11, pp. 1618-1631 . https://doi.org/10.1016/S1470-2045(21)00522-2
The Lancet. Oncology, 22(11), 1618-1631. Lancet Publishing Group
LANCET ONCOLOGY
r-IIB SANT PAU. Repositorio Institucional de Producción Científica del Instituto de Investigación Biomédica Sant Pau
instname
Dipòsit Digital de Documents de la UAB
Universitat Autònoma de Barcelona
The Lancet. Oncology
The Lancet. Oncology, 22(11), 1618-1631. Lancet Publishing Group
LANCET ONCOLOGY
r-IIB SANT PAU. Repositorio Institucional de Producción Científica del Instituto de Investigación Biomédica Sant Pau
instname
Dipòsit Digital de Documents de la UAB
Universitat Autònoma de Barcelona
The Lancet. Oncology
Funder: Victorian Cancer Agency
Funder: NIHR Manchester Biomedical Research Centre
Funder: Cancer Research UK
Funder: Cancer Council Tasmania
Funder: Instituto de Salud Carlos III
Funder: Cancer Australia
Funder: NIHR Ox
Funder: NIHR Manchester Biomedical Research Centre
Funder: Cancer Research UK
Funder: Cancer Council Tasmania
Funder: Instituto de Salud Carlos III
Funder: Cancer Australia
Funder: NIHR Ox
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::47cfb04c18b3df43fe6648bcca6209b5
https://doi.org/10.1016/S1470-2045(21)00522-2
https://doi.org/10.1016/S1470-2045(21)00522-2
Autor:
Rachel Pearlman, Sigurdis Haraldsdottir, Jessica Hemminger, Deborah Knight, Jon G. Jonasson, Wendy L. Frankel, Heather Hampel, Colin C. Pritchard
Publikováno v:
Human Pathology. 78:125-130
Lynch syndrome (LS) is the most common form of hereditary colon cancer. Germline mutations in the mismatch-repair (MMR) genes MLH1, MSH2 (EPCAM), MSH6, and PMS2, followed by a second hit to the remaining allele, lead to cancer development. Universal
Autor:
Thor Aspelund, Jon G. Jonasson, Matthías Halldórsson, Michael Hauptmann, Sigurdis Haraldsdottir, Kristín Huld Haraldsdóttir, Vilmundur Gudnason, Petur Snaebjornsson, Elias F. Gudmundsson
Publikováno v:
Scandinavian Journal of Gastroenterology. 53:972-975
Mismatch repair deficient (dMMR) colorectal cancer (CRC) is caused by inactivation of the MMR DNA repair system, most commonly via epigenetic inactivation of the MLH1 gene, and these tumors occur most frequently in the right colon. The objective was
Autor:
Christina Wu, Richard M. Goldberg, Xueliang Pan, Albert de la Chapelle, Peter G. Shields, Heather Hampel, Tanios Bekaii-Saab, Daniel Y. Weng, Sigurdis Haraldsdottir, Wendy L. Frankel
Publikováno v:
Genetics in medicine : official journal of the American College of Medical Genetics
Mismatch repair–deficient (dMMR) colorectal cancer (CRC) is caused by Lynch syndrome (LS) in 3% and sporadic inactivation of MLH1 by hypermethylation (MLH1-hm) in 12% of cases. It is not clear whether outcomes between LS-associated and MLH1-hm CRC
Autor:
Heather Hampel, Rachel Pearlman, Wendy L. Frankel, Sigurdis Haraldsdottir, Christina A. Arnold, Rachel Roth
Publikováno v:
Familial Cancer. 15:253-260
Universal screening for mismatch repair deficiency (dMMR) in cancer is increasingly being implemented to detect Lynch syndrome and aid in treatment decisions. The mismatch repair (MMR) immunohistochemistry (IHC) concordance rate between primary color
Autor:
Peter G. Shields, Heather Hampel, Tryggvi Stefansson, Megan P. Hitchins, Thorunn Rafnar, Colin C. Pritchard, Richard M. Goldberg, Gisli Masson, Jon G. Jonasson, Sigurdis Haraldsdottir, Tanios Bekaii-Saab, Petur Snaebjornsson, Fridbjorn Sigurdsson, Albert de la Chapelle, Sylvia Einarsdottir, Patrick Sulem, Reynir Arngrímsson, Birte Kehr, Asgeir Sigurdsson, Margret Steinarsdottir, Kari Stefansson, Kristin Alexiusdottir, Wendy L. Frankel, Daniel Weng, Stefan Haraldsson, Ahmet Yilmaz, Páll Helgi Möller
Publikováno v:
Nature Communications
Nature Communications, Vol 8, Iss 1, Pp 1-11 (2017)
Haraldsdottir, S, Rafnar, T, Frankel, W L, Einarsdottir, S, Sigurdsson, A, Hampel, H, Snaebjornsson, P, Masson, G, Weng, D, Arngrimsson, R, Kehr, B, Yilmaz, A, Haraldsson, S, Sulem, P, Stefansson, T, Shields, P G, Sigurdsson, F, Bekaii-Saab, T, Moller, P H, Steinarsdottir, M, Alexiusdottir, K, Hitchins, M, Pritchard, C C, de la Chapelle, A, Jonasson, J G, Goldberg, R M & Stefansson, K 2017, ' Comprehensive population-wide analysis of Lynch syndrome in Iceland reveals founder mutations in MSH6 and PMS2 ', Nature Communications, vol. 8, 14755 . https://doi.org/10.1038/ncomms14755
Nature Communications, Vol 8, Iss 1, Pp 1-11 (2017)
Haraldsdottir, S, Rafnar, T, Frankel, W L, Einarsdottir, S, Sigurdsson, A, Hampel, H, Snaebjornsson, P, Masson, G, Weng, D, Arngrimsson, R, Kehr, B, Yilmaz, A, Haraldsson, S, Sulem, P, Stefansson, T, Shields, P G, Sigurdsson, F, Bekaii-Saab, T, Moller, P H, Steinarsdottir, M, Alexiusdottir, K, Hitchins, M, Pritchard, C C, de la Chapelle, A, Jonasson, J G, Goldberg, R M & Stefansson, K 2017, ' Comprehensive population-wide analysis of Lynch syndrome in Iceland reveals founder mutations in MSH6 and PMS2 ', Nature Communications, vol. 8, 14755 . https://doi.org/10.1038/ncomms14755
Lynch syndrome, caused by germline mutations in the mismatch repair genes, is associated with increased cancer risk. Here using a large whole-genome sequencing data bank, cancer registry and colorectal tumour bank we determine the prevalence of Lynch
Autor:
Wendy L. Frankel, Jerneja Tomsic, Colin C. Pritchard, Rachel Pearlman, Heather Hampel, Albert de la Chapelle, Sigurdis Haraldsdottir
Publikováno v:
Gastroenterology. 147(6)
Background & Aims Patients with Lynch syndrome carry germline mutations in single alleles of genes encoding the mismatch repair (MMR) proteins MLH1, MSH2, MSH6, and PMS2; when the second allele becomes mutated, cancer can develop. Increased screening
Autor:
Stefan Haraldsson, Sigurdis Haraldsdottir, Sylvia Einarsdottir, Jon G. Jonasson, Richard M. Goldberg, Kari Stefansson, Tanios Bekaii-Saab, Patrick Sulem, Asgeir Sigurdsson, Heather Hampel, Albert de la Chapelle, Gisli Masson, Colin C. Pritchard, Birte Kehr, Thorunn Rafnar, Ahmet Yilmaz, Megan P. Hitchins, Wendy L. Frankel, Daniel Weng, Petur Snaebjornsson
Publikováno v:
Journal of Clinical Oncology. 34:1542-1542
1542Background: Lynch syndrome (LS) is caused by germline mutations in mismatch repair (MMR) genes (MLH1, MSH2, MSH6, PMS2) or EPCAM, and is associated withincreased cancer risk. The incidence of LS in Iceland is unknown. We investigated the incidenc
Autor:
Edward H. Lin, Angela Jacobson, Stacey Shiovitz, Paul J. Goodfellow, Colin C. Pritchard, David E. Cohn, Mallory Beightol, Emily H. Turner, Albert de la Chapelle, Stephen J. Salipante, Heather Hampel, Mark Arnold, Sigurdis Haraldsdottir, Jonathan F. Tait, William M. Grady, Ted Gooley
Publikováno v:
Journal of Clinical Oncology. 33:3550-3550
3550 Background: Double somatic mutations in mismatch repair (MMR) genes have recently been described in a high proportion of colorectal and endometrial cancers with microsatellite instability (MSI...