Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Pierre-Luc Germain"'
Despite the importance of microRNAs (miRNAs) in regulating a broad variety of biological processes, accurately predicting the transcripts they repress remains a challenge. Recent research suggests improved miRNA target prediction using a biochemical
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4ddc7c41bb4cdfb7c8de3b8775dd55ca
https://doi.org/10.1101/2021.06.16.448293
https://doi.org/10.1101/2021.06.16.448293
BackgroundDespite the importance of alternative poly-adenylation and 3’ UTR length for a variety of biological phenomena, there are limited means of detecting UTR changes from standard transcriptomic data.ResultsWe present thediffUTRBioconductor pa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::30fa782f0c76b8c09236c6e41a78303e
https://doi.org/10.1101/2021.02.12.430963
https://doi.org/10.1101/2021.02.12.430963
Autor:
Mark D. Robinson, Dheeraj Malhotra, Catarina Raposo, Helena L. Crowell, Charlotte Soneson, Daniela Calini, Pierre-Luc Germain, Ludovic Collin
Publikováno v:
Nature Communications
Nature Communications, 11 (1)
Nature Communications, Vol 11, Iss 1, Pp 1-12 (2020)
Nature Communications, 11 (1)
Nature Communications, Vol 11, Iss 1, Pp 1-12 (2020)
Single-cell RNA sequencing (scRNA-seq) has become an empowering technology to profile the transcriptomes of individual cells on a large scale. Early analyses of differential expression have aimed at identifying differences between subpopulations to i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5ee570e77c0ae5dd9964224e7e12477e
https://www.zora.uzh.ch/id/eprint/197427/
https://www.zora.uzh.ch/id/eprint/197427/
Publikováno v:
F1000Research. 10:979
Doublets are prevalent in single-cell sequencing data and can lead to artifactual findings. A number of strategies have therefore been proposed to detect them. Building on the strengths of existing approaches, we developed scDblFinder, a fast, flexib
Autor:
Giuseppe Testa, Pierre-Luc Germain
Publikováno v:
Stem Cell Reports, Vol 8, Iss 6, Pp 1784-1796 (2017)
Stem Cell Reports
Stem Cell Reports
Summary Both the promises and pitfalls of the cell reprogramming research platform rest on human genetic variation, making the measurement of its impact one of the most urgent issues in the field. Harnessing large transcriptomics datasets of induced
Autor:
Mark D. Robinson, Catarina Raposo, Helena L. Crowell, Charlotte Soneson, Daniela Calini, Ludovic Collin, Dheeraj Malhotra, Pierre-Luc Germain
Single-cell RNA sequencing (scRNA-seq) has quickly become an empowering technology to profile the transcriptomes of individual cells on a large scale. Many early analyses of differential expression have aimed at identifying differences between subpop
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dd13b41ae9bc781b9294e5676360b89a
https://doi.org/10.1101/713412
https://doi.org/10.1101/713412
Autor:
Antonio Adamo, Pierre-Luc Germain, Alessandro Vitriolo, Pasquale Laise, Giuseppe Testa, Vivek Das
Publikováno v:
Nucleic Acids Research
RNA sequencing (RNAseq) has become the method of choice for transcriptome analysis, yet no consensus exists as to the most appropriate pipeline for its analysis, with current benchmarks suffering important limitations. Here, we address these challeng
Autor:
Ruedi Aebersold, Isabel Sorg, Hui-Xia Zhou, Stylianos E. Antonarakis, Wolf-Dietrich Hardt, Yansheng Liu, Christelle Borel, Isabell Bludau, Christoph Dehio, Fedor Bezrukov, Y Mi, Michael Seifert, A Drogen Van, Mario Emmenlauer, Max Frank, Giuseppe Testa, Pierre-Luc Germain, Evan G. Williams, F Bena Sloan, Martin Mehnert, T Mueller, Julio Saez-Rodriguez, Saskia Kreibich
The independent reproduction of research results is a cornerstone of experimental research, yet it is beset by numerous challenges, including the quality and veracity of reagents and materials. Much of life science research depends on life materials,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fb52ddf5737f2e021edf28ceb6d441b4
https://doi.org/10.1101/307421
https://doi.org/10.1101/307421
Autor:
Wieland Kiess, Giuseppe D'Agostino, Eewa Nånberg, Sebastiano Trattaro, Åke Bergman, Rantakkoko P, Chris Gennings, Leemans M, Carl G. Bornehag, Matteo Zanella, Filip Rendel, Pauliina Damdimopoulou, Vesna Munic Kos, Giuseppe Testa, Demeneix B, Cavallo F, Efthymia Kitraki, Fini J, Raul Bardini Bressan, Chorev Ne, Joachim Sturve, Joëlle Rüegg, Birgitta E. Sundström, Steven M. Pollard, Christina Rudén, Nicolò Caporale, Birgersson L, Pierre-Luc Germain, Alejandro Lopez Tobon, Borbély G, Jönsson M, Hannu Kiviranta, Olle Söder, Lazzarin M, Mattias Öberg
Convergent evidence associates endocrine disrupting chemicals (EDCs) with major, increasingly-prevalent human disorders. Regulation requires elucidation of EDC-triggered molecular events causally linked to adverse health outcomes, but two factors lim
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9c48cdda85e2bd85f6618bd93559608a