Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Jonathan Hall"'
Publikováno v:
Chemistry (Weinheim an Der Bergstrasse, Germany)
MicroRNAs constitute a class of endogenous, non‐coding RNAs that influence various processes within the cell. By base‐pairing to partially‐complementary sites located in the 3’ untranslated region of target messenger RNAs, microRNAs participa
Autor:
Sambuddha Banerjee, Mina N. Chanakira, Jonathan Hall, Alexa Kerkan, Saumya Dasgupta, Daniel W. Martin
Publikováno v:
Journal of inorganic biochemistry. 229
Iron is an essential yet toxic micronutrient and its transport across biological membranes is tightly regulated in all living organisms. One such iron transporter, the Ftr-type permeases, is found in both eukaryotic and prokaryotic cells. These Ftr-t
Autor:
Jonathan Hall, Luca F R Gebert, Artur Laski, Souvik Ghosh, Anna L. Malinowska, Mark D. Robinson, Yuluan Wang, Charlotte Soneson, Alexander Kanitz
Publikováno v:
Nucleic Acids Research
Nucleic Acids Research, 49 (1)
Nucleic Acids Research, 49 (1)
Many microRNAs regulate gene expression via atypical mechanisms, which are difficult to discern using native cross-linking methods. To ascertain the scope of non-canonical miRNA targeting, methods are needed that identify all targets of a given miRNA
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::20a8cc28e69a441baeca93585424bcc3
https://www.zora.uzh.ch/id/eprint/197428/
https://www.zora.uzh.ch/id/eprint/197428/
Publikováno v:
Chimia, 73 (5)
CHIMIA, Vol 73, Iss 5 (2019)
CHIMIA, Vol 73, Iss 5 (2019)
Advances in the chemical synthesis of RNA have opened new possibilities to address current questions in RNA biology. Access to site-specifically modified oligoribonucleotides is often a pre-requisite for RNA chemical-biology projects. Driven by the e
Publikováno v:
FEBS lettersReferences. 593(16)
G-quadruplexes are secondary structures formed in G-rich sequences in DNA and RNA. Considerable research over the past three decades has led to in-depth insight into these unusual structures in DNA. Since the more recent exploration into RNA G-quadru
Autor:
Christian Berk, Jonathan Hall, Gerald Schwank, Natasa Savic, Martin Jinek, Femke Ringnalda, Katja Bargsten
The CRISPR-Cas9 system is a powerful genome-editing tool that promises application for gene editing therapies. The Cas9 nuclease is directed to the DNA by a programmable single guide (sg)RNA, and introduces a site-specific double-stranded break (DSB)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b5cba8b3488fdc02002a560c08db945a
https://www.zora.uzh.ch/id/eprint/174011/
https://www.zora.uzh.ch/id/eprint/174011/
Autor:
Jonathan Hall, Evangelia Lekka
Publikováno v:
FEBS Letters, 592 (17)
Febs Letters
Febs Letters
Noncoding RNAs are emerging as potent and multifunctional regulators in all biological processes. In parallel, a rapidly growing number of studies has unravelled associations between aberrant noncoding RNA expression and human diseases. These associa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::43bf4fab5e8293fb345452b9d6e7a9d8
https://hdl.handle.net/20.500.11850/289919
https://hdl.handle.net/20.500.11850/289919
Autor:
Dario Neri, Gerald Schwank, Constance Ciaudo, Helen Lindsay, Yizhou Li, Femke Ringnalda, Natasa Savic, Jonathan Hall, Martin Jinek, Christian Berk, Katja Bargsten, Mark D. Robinson
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::953fe638cbf91ea7fb94536b34dceb2e
https://doi.org/10.7554/elife.33761.032
https://doi.org/10.7554/elife.33761.032
Autor:
Dario Neri, Christian Berk, Gerald Schwank, Jonathan Hall, Femke Ringnalda, Yizhou Li, Katja Bargsten, Martin Jinek, Natasa Savic
The CRISPR/Cas9 targeted nuclease technology allows the insertion of genetic modifications with single base-pair precision. The preference of mammalian cells to repair Cas9-induced DNA double-strand breaks via non-homologous end joining (NHEJ) rather
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ebeae678e3d1e8eac5a9cf677a2abaca
https://doi.org/10.1101/218149
https://doi.org/10.1101/218149
Autor:
Anneke Brümmer, Jonathan Hall, Nitish Mittal, André P. Gerber, Panagiota Tsikrika, Shivendra Kishore, Jochen Imig, Boris Guennewig, Mihaela Zavolan, Andreas Brunschweiger
Publikováno v:
Nature Chemical Biology
Identifying the interaction partners of noncoding RNAs is essential for elucidating their functions. We have developed an approach, termed microRNA crosslinking and immunoprecipitation (miR-CLIP), using pre-miRNAs modified with psoralen and biotin to